Search Results - wound+healing

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A Highly Elastic and Tough Hydrogel for Efficient Hemostasis and Closure of Injured Internal Organs in Emergency Healthcare (UCLA Case No. 2024-001)
A research group at UCLA’s Department of Chemical and Biomedical Engineering designed a novel, customizable bioadhesive that can stop bleeding quickly and effectively in injured tissue. BACKGROUND: Traumatic injuries that involve excessive bleeding are a significant cause of mortality world-wide and account for as much as 40% of preventable...
Published: 9/26/2024   |   Inventor(s): Nasim Annabi
Keywords(s): bioadhesives, hemostasis, material science, tissue repair, Wound Healing
Category(s): Chemical > Polymers, Chemical > Coatings, Adhesives & Inks, Materials > Functional Materials, Materials > Membranes
Aesthetics and Wound Healing-related Technologies
NU2014-173; NU2014-168; NU2015-071; NU2015-101; NU2017-011; NU2018-071; NU2018-151; NU2020-033; NU2020-249; NU2022-016; NU2022-079; NU2024-094 Transform your wound care and tissue repair solutions with our portfolio of technologies that provide cutting-edge solutions for wound care, tissue engineering, and disease treatment. This includes hydrogels...
Published: 9/10/2024   |   Inventor(s):  
Keywords(s): Adhesive, Biomedical, Biotechnology, General surgery, Hydrogel, Wound Healing
Category(s): Life Sciences > Therapeutics, Life Sciences > Healthcare Devices, Tools & IT
Functionalized Materials for Surgical Closure Device (Case No. 2022-270)
Summary: UCLA researchers in the Department of Urology have developed a synthetic functionalized adhesive material that can be utilized for various purposes including wound closure. Background: Synthetic materials and adhesive polymers such as poly (glycerol sebacate) or PGS are often used in tissue engineering and medical devices. Such materials...
Published: 9/11/2024   |   Inventor(s): Renea Sturm, George Aninwene
Keywords(s): adhesive material, Biomaterial, Composite Material, Composite Materials, Functional Materials, internal suture lines, luminal repairs, Materials, Medical Device, Medical Devices and Materials, Smart medical device, suture line reinforcement, Urology, wearable medical device, Wound closure, Wound Healing
Category(s): Medical Devices, Medical Devices > Surgical Tools, Materials, Materials > Functional Materials, Materials > Membranes, Chemical, Chemical > Polymers
Nitric Oxide-Releasing Polysaccharide Materials
Abstract: Diazeniumdiolates comprise a diverse class of NO-releasing compounds and materials that are known to exhibit sufficient stability to be useful as therapeutics. Diazeniumdiolated compounds have been attached to polymers, substrates, and medical devices for the treatment and management of a variety of diseases including cancer, inflammation,...
Published: 5/22/2024   |   Inventor(s): Joseph Hrabie, Larry Keefer
Keywords(s): bandages, biofilm dispersal, Cellulose, Diazeniumdiolate, Nitric Oxide (NO), POLYSACCHARIDE, Wound healing
Category(s): Collaboration Sought > Materials Available, TherapeuticArea > Immunology, Collaboration Sought > Licensing, Application > Therapeutics
Topical Antibiotic for Faster Wound Healing
Abstract: Currently available topical antibiotic formulations effectively eliminate bacteria at a wound site. Eliminating bacteria in the wound also eliminates the molecular signals present in bacterial DNA that stimulate the immune system's wound healing processes. Without these signals, the rate of wound healing is diminished.   The present technology...
Published: 5/22/2024   |   Inventor(s): Dennis Klinman, Hiroyasu Ito
Keywords(s): CpG motifs, Immunostimulation, ODN., Oigodeoxynucleotides, TLR7, TLR9, Wound healing
Category(s): TherapeuticArea > Dermatology, Collaboration Sought > Licensing, Application > Therapeutics
Nitric Oxide-Releasing Polymers for Wound Healing
Abstract:  A number of factors can play a detrimental role in the process of wound healing such as poor nutritional status, smoking, various drugs, cancer, and diabetes.  Wound healing impairment is a challenging clinical problem with no efficacious treatments currently available.  Nitric oxide (NO) has been shown to play a role in the process of wound...
Published: 5/22/2024   |   Inventor(s): Joseph Hrabie, Larry Keefer
Keywords(s): Bioabsorption, Dermatological conditions, nitric oxide, Polyvinyl Pyrrolidone (povidone), Wound healing
Category(s): TherapeuticArea > Immunology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Dermatology, Application > Therapeutics
Topical Sodium Nitrate Ointment for Sickle Cell Disease
Abstract: Chronic leg ulcers are a debilitating vasculopathic complication for some patients with sickle cell disease (SCD). Prevalence of leg ulcers varies based on age and geographic location; about 5-10% of all SCD patients may suffer leg ulcers. These leg ulcers are painful, result in infections, hospitalization, disability, and negatively impact...
Published: 4/8/2024   |   Inventor(s): Haksong Jin, George Grimes, Deborah Sperling, Gopal Potti, Caterina Minniti-Crouch, Gregory Kato
Keywords(s): Blood Disorder, CREAM, Haksong, nitric oxide, Ointment, SCD, sickle cell disease, Sodium Nitrate, TOPICAL, Topical Therapeutic, Vascular Ulcers, Wound healing
Category(s): TherapeuticArea > Endocrinology, Application > Therapeutics, TherapeuticArea > Cardiology, Collaboration Sought > Licensing
Self-Deliverable siRNA to Prevent Corneal Scarring
Targeted gene silencing technology promotes corneal wound healing. Background: Ocular scarring after surgery, trauma, or infection leads to vision loss and blindness. Blindness due to corneal scarring can currently only be resolved by transplantation, necessitating new approaches in regenerative wound healing in the eye. Technology Overview:...
Published: 9/24/2024   |   Inventor(s): Audrey Bernstein
Keywords(s): cornea, fibrosis, integrin, myofibroblast, scarring, wound healing
Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Healthcare, Campus > Upstate Medical University
Iodinated Salicylate-Polymers
​ ​ FIG. 2( a) is a cross-sectional view of an apparatus or article including a medical device and an iodinated polymer coating in accordance with some embodiments. FIG. 2( b) is a perspective view of the medical device, shown in FIG. 2( a), having a surface that is partially coated with the iodinated polymer coating in accordance...
Published: 9/23/2024   |   Inventor(s): Kathryn Uhrich, Ashley Carbone
Keywords(s): Anti-cancer, Drug Delivery, Imaging, Implants, Polymers & Composites, Wound healing
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics, Technology Classifications > Polymers/Composites/Materials
Biodegradable and Versatile Copolymers to Promote Wound Healing
Invention Summary: Wound healing is a complex and dynamic process of replacing devitalized and missing cellular structures and tissue layers and thus there is a need for a biodegradable and versatile copolymers to promote wound healing. Rutgers scientists have developed a copolymer formulation to stably release salicylic acid (SA). It holds the promise...
Published: 11/1/2024   |   Inventor(s): Kathryn Uhrich, Sabrina Snyder
Keywords(s): Biomaterials, Drug Delivery, Neurological disorder & neuropathic pain, Wound healing
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
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