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Search Results - osteoporosis
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2020-753 PREVENTING SKELETAL AGING AND
OSTEOPOROSIS
UCLA Researchers in the Department of Dentistry have discovered that a novel drug combination results in a synergistic therapeutic effect for
osteoporosis
treatment. BACKGROUND: It is estimated that 10 million men and women in the U.S. suffer from osteoporosis; a metabolic bone disease that is characterized by low bone density and deterioration...
Published: 7/19/2023
|
Inventor(s):
Cun-Yu Wang
Keywords(s):
Osteo
,
Osteoporosis
Category(s):
Therapeutics > Musculoskeletal Disease
Maspin for
Osteoporosis
Treatment
NU 2007-156 Inventors Ming Zhang Short Description Maspin, a tumor-suppressing protein, stimulates bone cell proliferation for treatment of
osteoporosis
AbstractA Northwestern researcher has discovered that maspin, a well-known anti-cancer protein, can also stimulate proliferation of bone cells. Maspin is able to modulate osteoblast proliferation...
Published: 7/3/2024
|
Inventor(s):
Keywords(s):
Biologic
,
Osteoporosis
,
Therapeutics
Category(s):
Life Sciences > Therapeutics
A Functional Monoclonal Antibody Against DC-STAMP
Brief Description: Bone is a very dynamic organ as evidenced by the process of bone remodeling which relies on a delicate balance between bone formation and bone resorption and is orchestrated by osteoblasts (OB) and osteoclasts (OC). The coordinated interplay of OB and OC continuously remodels bone through highly regulated molecular and cellular...
Published: 5/7/2024
|
Inventor(s):
Kofi Mensah
,
Yahui Grace Chiu
,
Christopher Ritchlin
,
Edward Schwarz
Keywords(s):
Antibody
,
Anti-inflammatory
,
Inflammation
,
Orthopaedics
,
Osteoporosis
,
Reagent
Category(s):
Research Tools
Novel agents and methods for treating metabolic bone disorders and other conditions
Project ID: D2014-15IP Status: Provisional patent #62/115,786Invention Description: Methods of generating and administering digestion products of FDA-approved low acyl gellan gum (LA-GAGR) to produce mega-GAGR, midi-GAGR, and mini-GAGR and administration thereof. Applications: Compositions comprising midi- and/or mini-GAGR have been shown to be useful...
Published: 8/3/2022
|
Inventor(s):
Dong Shik Kim
,
Joshua Park
Keywords(s):
Bone Cell Formation
,
Metabolic Bone Diseases
,
Osteogenesis
,
Osteoporosis
Category(s):
Mouse Model of Osteoarthritis
Applications: Osteoarthritis (OA) is a common degenerative joint disease and currently there is no effective treatment for the diseases. We have generated a conditional activation genetic mouse model that can help to identify new drugs for the prevention and treatment of osteoarthritis. The mouse model can also test the effect and efficacy...
Published: 5/7/2024
|
Inventor(s):
Di Chen
Keywords(s):
Mouse
,
Orthopaedics
,
Osteoporosis
Category(s):
Research Tools