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Search Results - osteoporosis
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Novel Therapeutics for
Osteoporosis
, Osteoarthritis and Other Musculoskeletal Diseases
Project ID: D2013-47 Novelty: Three categories of drug-like molecules that have been identified to promote bone and cartilage formation from stem cells. Value Proposition:
Osteoporosis
and Osteoarthritis are complex musculoskeletal diseases that are prevalent in the aging population. Worldwide,...
Published: 4/20/2026
|
Updated: 4/20/2026
|
Inventor(s):
Bruce Heck
,
Dong Hyun "Danny" Kim
,
Paul Erhardt
,
Brian Kress
Keywords(s):
Agonists
,
Antagonists
,
Musculoskeletal
,
Osteoarthritis
,
Osteoporosis
Category(s):
Long Bone/Joint Repair
Preventing Skeletal Aging and
Osteoporosis
(UCLA Case No. 2020-753)
UCLA Researchers in the Department of Dentistry have discovered that a novel drug combination results in a synergistic therapeutic effect for
osteoporosis
treatment. BACKGROUND: It is estimated that 10 million men and women in the U.S. suffer from osteoporosis; a metabolic bone disease that is characterized by low bone density and deterioration...
Published: 7/17/2025
|
Updated: 5/17/2021
|
Inventor(s):
Cun Yu Wang
Keywords(s):
Osteo
,
Osteoporosis
Category(s):
Therapeutics > Musculoskeletal Disease
A Functional Monoclonal Antibody Against DC-STAMP
Brief Description: Bone is a very dynamic organ as evidenced by the process of bone remodeling which relies on a delicate balance between bone formation and bone resorption and is orchestrated by osteoblasts (OB) and osteoclasts (OC). The coordinated interplay of OB and OC continuously remodels bone through highly regulated molecular and cellular...
Published: 7/1/2025
|
Updated: 7/24/2018
|
Inventor(s):
Kofi Mensah
,
Yahui Grace Chiu
,
Christopher Ritchlin
,
Edward Schwarz
Keywords(s):
Antibody
,
Anti-inflammatory
,
Inflammation
,
Orthopaedics
,
Osteoporosis
,
Reagent
Category(s):
Research Tools
Novel agents and methods for treating metabolic bone disorders and other conditions
Project ID: D2014-15IP Status: Provisional patent #62/115,786Invention Description: Methods of generating and administering digestion products of FDA-approved low acyl gellan gum (LA-GAGR) to produce mega-GAGR, midi-GAGR, and mini-GAGR and administration thereof. Applications: Compositions comprising midi- and/or mini-GAGR have been shown to be useful...
Published: 8/3/2022
|
Updated: 6/17/2015
|
Inventor(s):
Dong Shik Kim
,
Joshua Park
Keywords(s):
Bone Cell Formation
,
Metabolic Bone Diseases
,
Osteogenesis
,
Osteoporosis
Category(s):
Mouse Model of Osteoarthritis
Applications: Osteoarthritis (OA) is a common degenerative joint disease and currently there is no effective treatment for the diseases. We have generated a conditional activation genetic mouse model that can help to identify new drugs for the prevention and treatment of osteoarthritis. The mouse model can also test the effect and efficacy...
Published: 5/7/2024
|
Updated: 4/10/2009
|
Inventor(s):
Di Chen
Keywords(s):
Mouse
,
Orthopaedics
,
Osteoporosis
Category(s):
Research Tools