Search Results - donald+ronning

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Novel Isoselenazolone Derivatives Show Effectiveness Against Multiple Human Disease-causing Pathogens
Project ID: D2015-17Invention Description:Neurodegenerative, inflammatory and other physiological diseases are linked to the activity of reactive oxygen species (ROS). Glutathione peroxidase is a Selenium-based enzyme that has been shown to protect biomembranes and other cellular components from damage caused by ROS, by scavenging hydrogen peroxide...
Published: 6/18/2024   |   Inventor(s): Steven Sucheck, Donald Ronning, Sandeep Thanna, Alexander Landgraf
Keywords(s): Antibiotics, Anti-inflammatory, Antioxidant, Bipolar, Cancer, Cytoprotective, Hearing, Neurodegenerative, Reperfusion, Stroke
Category(s): Inflammation & Immunity
E. Coli plasmid (pET32) encoding MTA/SAH nucleosidase
Project ID: D2011-29 Gene: ‘pfs’ gene from H. pylori (strain J99) genomic DNA Enzyme encoded: 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase Plasmid: pET32 Description: The bacterial enzyme 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTAN) plays a central role in three essential metabolic pathways...
Published: 6/18/2024   |   Inventor(s): Donald Ronning
Keywords(s): Autoinducer II, H. Pylori, MTAN, pET32, pfs gene
Category(s): Tools
M. Tuberculosis Drug Molecules Screening Assay
Project ID: D2011-63Novelty: The disclosed invention is a simple and efficient high-throughput assay to screen small molecule drug and drug-like compounds for their effectiveness against Mycobacterium Tuberculosis (M. tb) and other bacterium.Value Proposition:M. tb is a form of tuberculosis that is resistant to two or more of the primary drugs (e.g.,...
Published: 5/9/2024   |   Inventor(s): Donald Ronning, James Franco
Keywords(s): Protein-DNA complexation, Screening, Tuberculosis
Category(s): Tools