Search Results - cell-free+dna

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Physical Separation of Ultrashort Single-Stranded Cell-Free DNA in Biofluids Using Differential Filtration and Next-Generation Sequencing Pipeline to Detect Methylation Status of Ultrashort Single-Stranded Cell-Free DNA (UCLA 2023-077, 2023-082)
UCLA researchers in the Department of Dentistry have established novel extraction and bioinformatics pipeline of ultrashort single-stranded cell-free DNA for the use in liquid biopsy diagnostics. BACKGROUND: Liquid biopsy is a critical diagnostic tool for various human diseases. The rapid market growth of liquid biopsy is primarily driven by novel...
Published: 7/1/2024   |   Inventor(s): David Wong
Keywords(s): Cancer, cell-free DNA, circulating DNA, Diagnostic Markers & Platforms, DNA methylation, liquid biopsy, next generation sequencing (NGS)
Category(s): Software & Algorithms > Bioinformatics, Life Science Research Tools > Research Methods, Platforms > Diagnostic Platform Technologies
INTEGRATED HOST-MICROBE METAGENOMICS OF CELL-FREE NUCLEIC ACID FOR SEPSIS DIAGNOSIS
INTEGRATED HOST-MICROBE METAGENOMICS OF CELL-FREE NUCLEIC ACID FOR SEPSIS DIAGNOSIS Researchers at UCSF and the Chan Zuckerberg Institute have developed a single-sample metagenomic approach combining host transcriptional profiling with unbiased pathogen detection to improve sepsis diagnosis. Sepsis causes 20% of all deaths globally and contributes...
Published: 9/14/2023   |   Inventor(s): Charles (Chaz) Langelier, Katrina Kalantar, Lucile Neyton, Carolyn Calfee
Keywords(s): Cell-Free DNA, cfDNA, Diagnosis, Next Generation Sequencing (NGS), Sepsis
Category(s): Technology Classifications > Biology
NON-INVASIVE PRENATAL DIAGNOSIS OF SINGLE GENE DISORDERS USING DROPLET DIGITAL PCR
NON-INVASIVE PRENATAL DIAGNOSIS OF SINGLE GENE DISORDERS USING DROPLET DIGITAL PCR Researchers at the Chan Zuckerberg Biohub and Stanford have developed non-invasive methods for detection of fetal autosomal recessive and X-linked diseases during pregnancy. Pre-natal diagnosis of single gene disorders often requires the use of invasive techniques...
Published: 3/17/2023   |   Inventor(s): Stephen Quake, Joan Camunas-Soler
Keywords(s): Autosomal Recessive, Cell-Free DNA, cfDNA, Circulating Cell-Free DNA, Droplet Digital PCR, Fetal Diagnosis, Maternal Blood, Maternal Plasma, Prenatal Diagnosis, X-Linked
Category(s): Technology Classifications > Biology