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Lesion Estimation with Geometric Object Measurement (LE-GEOM) (Case No. 2025-077)
Summary: UCLA researchers in the Department of Radiology have developed a novel, automated approach for tumor assessment by determining RANO-compliant tumor diameters from tumor segmentation data. Background: MRI tumor measurements are critical in both clinical trials and clinical practice. Traditionally, radiologists manually assessed tumors by...
Published: 1/29/2026   |   Inventor(s): Benjamin Ellingson, Francesco Sanvito, Catalina Raymond
Keywords(s):  
Category(s): Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Medical Devices, Medical Devices > Medical Imaging, Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Image Processing, Software & Algorithms > Bioinformatics
Poly(phenylene sulfide) Gels and Aerogels
THE CHALLENGE The key challenge in commercializing high-performance porous materials like poly(phenylene sulfide) aerogels lies in the complex, costly, and environmentally taxing manufacturing processes currently required. Traditional methods depend on toxic or high-boiling-point solvents and energy-intensive drying techniques such as supercritical...
Published: 1/29/2026   |   Inventor(s): Robert Moore, Garrett Godshall, Christopher Williams, Daniel Rau
Keywords(s):  
Category(s): Technology Classifications > Chemicals/Materials
Polyaryletherketone (paek) Gels and Aerogels
THE CHALLENGE Developing lightweight high-performance aerogels from advanced polymers like PEEK and PEKK presents a major business and manufacturing challenge due to the complex and costly processing these materials require. Their exceptional thermal and chemical stability make them ideal for demanding applications in aerospace energy and environmental...
Published: 1/29/2026   |   Inventor(s): Robert Moore, Glenn Spiering, Michelle Pomatto
Keywords(s):  
Category(s): Technology Classifications > Chemicals/Materials
Polyester Gels and Aerogels
THE CHALLENGE Polymer aerogels offer a unique combination of ultralow density, high porosity, and very low thermal conductivity, making them highly promising for industrial applications in energy storage, aerospace, filtration, and thermal insulation. Their lightweight and tunable mechanical properties give them an edge over traditional materials...
Published: 1/29/2026   |   Inventor(s): Robert Moore, Garrett Godshall
Keywords(s):  
Category(s): Technology Classifications > Chemicals/Materials, Technology Classifications > Additive Manufacturing
ScarNet: A Novel Foundation Model for Automated Myocardial Scar Quantification from Late Gadolinium-Enhancement Images
SHORT DESCRIPTION ScarNet is an AI-powered foundation model that automates myocardial scar detection from cardiac MRI images with high accuracy and rapid processing for clinical decision-making. INVENTORS Daniel Kim*, PhD Knight Family Professor of Cardiac Imaging & Professor of Radiology, Northwestern University Feinberg...
Published: 1/29/2026   |   Inventor(s):  
Keywords(s):  
Category(s): Physical Sciences > Software & Services
Non-invasive Diagnostic for Meningiomas
Application A non-invasive molecular diagnostic tool that reliably predicts the tumor characteristics and risk of recurrence of meningiomas. Key Benefits Combines meningioma gene expression data, construction of a gene interaction network, and tumor histology data to diagnose and predict clinical outcomes. Complete analytical handling from specimen...
Published: 1/28/2026   |   Inventor(s): Ali Alawieh, Youssef Ismail, Tomas Garzon-Muvdi
Keywords(s): Algorithm, AI, and Machine Learning, Biomarkers, Oncology Treatments, Personalized Medicine, Platform, Screening Assays
Category(s): TechPub Algolia > Diagnostics
Sulfonyl-triazole activators for cell-selective glycolysis enhancement in cancer and Parkinson’s disease
Background Cellular metabolism is a central regulator of immune cell function and neuronal survival, making it a promising therapeutic target in both cancer and neuro­degenerative disease. In solid tumors, tumor-infiltrating lymphocytes (TILs) frequently succumb to metabolic exhaustion due to the nutrient-depleted and immunosuppressive microenvironment,...
Published: 1/27/2026   |   Inventor(s): Ku-Lung Hsu, Xiaoding Jiang, Xiaolu Cambronne
Keywords(s):  
Category(s): Life sciences > Therapeutics > Formulation, Life sciences > Therapeutics > Drug discovery
Microneedle array coating technology for enhanced stability and targeted delivery of mRNA and biologics
A microneedle-based system uses cryogenically pre-cooled needles coated via thin-film freeze-coating to preserve mRNA stability, enabling efficient, multi-therapeutic intradermal delivery of temperature-sensitive drugs. Background The field of advanced drug delivery systems has grown substantially as the biomedical industry grapples with the complexities...
Published: 1/27/2026   |   Inventor(s): Zhengrong Cui, Michael Sandoval, Robert Williams, Drew Weissman, Qin Li
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug discovery
A microneedle-based resonant sensor system for continuous, wireless monitoring of wound and physiological states
This technology uses gold-coated microneedles and wireless sensors to directly sample wound fluid, detecting infection and other changes in real time. Data is analyzed with machine learning and sent to clinicians for early, continuous wound monitoring. Background Wound monitoring is a critical aspect of healthcare, especially for patients recovering...
Published: 1/27/2026   |   Inventor(s): James Clarke, Miles Massidda, Joseph Schmidt, Cristina Checka, Scott Alpard
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices
Misalignment Resilient Diffractive Optical Networks (Case No. 2020-885)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed and experimentally validated a comprehensive training scheme that greatly enhances the robustness of diffractive networks to 3D misalignments and fabrication tolerances in their physical implementation. Background: As an optical machine learning framework,...
Published: 1/28/2026   |   Inventor(s): Aydogan Ozcan
Keywords(s): Optical Communication , Optical computing, optical implementation, Optical networks, optical processor
Category(s): Software & Algorithms, Software & Algorithms > Image Processing, Optics & Photonics
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