Search Results - platform+technology

40 Results Sort By:
A Fully Automated, Origami-Inspired Approach for Manufacturing Self-Assembling, Self-Reconfiguring, and Reprogrammable Structures.
An origami-based approach to generate complex shapes by folding magnetically programmed sheets. Problem: Shape-changing materials are desirable in applications such as soft robotics, implantable and wearable devices, minimally invasive medicine, and micromachines. Common control signals used for self-folding, such as temperature, diffusion, and capillary...
Published: 8/14/2024   |   Inventor(s): Cynthia Sung, Gabriel Unger
Keywords(s): Electronic Materials, Nanotechnology, Platform Technology
Category(s): Technology Classifications > Robotics
Biocompatible, Reversible, and Strong Multilayered Tape for Advanced Wound Care
A hydrogel-based adhesive with a hydrophobic backing layer protects it from exposure to water and offers painless removal and easy repositioning. Problem: Reversible adhesives have gained popularity in industries with a growing emphasis on reducing waste and improving sustainability. Previously, the inventors have developed a strong and reversible adhesive...
Published: 7/23/2024   |   Inventor(s): Shu Yang, Baohong Chen, Alexander Tucker
Keywords(s): Bioengineering, Hydrogels, Platform Technology, Soft Materials
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Materials
Targeted Organ or Multiple Organ Delivery of mRNA with Ionizable Amphiphilic Janus Dendrimers
A library of easily synthesized ionizable amphiphilic Janus dendrimer (IAJD) compounds that deliver mRNA either to targeted organs or multiple organs, depending on the IAJD design. Problem: Four-component lipid nanoparticles (LNPs) are the benchmark synthetic vector for the delivery of mRNA. Despite their high biosafety, low toxicity, and immunogenicity,...
Published: 7/23/2024   |   Inventor(s): Virgil Percec, Drew Weissman, Juncheng (Luke) Lu, Elena Atochina-Vasserman, Devendra Maurya, Dipankar Sahoo
Keywords(s): Drug Delivery, Platform Technology
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Vaccines
Deep Learning Model Discovers Antibiotic Drugs in Extinct Organisms Effective Against Drug-Resistant Superbugs
Antibiotic Peptide de-extinction (APEX) is a deep-learning AI solution that can unearth ancient antibiotics to effectively combat superbugs and tackle antibiotic resistance on a global scale. Problem: Escalating antibiotic resistance around the globe has emerged as one of the pressing problems of our time, with antibiotic-resistant infections causing...
Published: 6/27/2024   |   Inventor(s): Cesar de la Fuente-Nunez, Marcelo Der Torossian Torres, Fangping Wan
Keywords(s): Bioengineering, Infectious Disease, Platform Technology, Protein/Peptide (Non-Antibody)
Category(s): Technology Classifications > Therapeutics
Strategies for Mitigating Acute Side Effects of Lung-Targeted Nanocarriers
Approaches and Design Techniques to Alleviate Coagulation-Related Acute Side Effects of Lung-Targeted Nanocarriers Problem: Lipid nanoparticles (LNPs) play a crucial role in drug delivery, enabling targeted drug administration to specific tissues. LNPs tailored for lung-specific delivery often incorporate cationic (positively charged) lipids. Unfortunately,...
Published: 6/26/2024   |   Inventor(s): Jacob Brenner, Vladimir Muzykantov, Jacob Myerson, Oscar Marcos Contreras, Marco Zamora, Serena Omo-Lamai
Keywords(s): Bioengineering, Drug Delivery, Gene Editing, Gene Therapy, Nanotechnology, Platform Technology, Pulmonary
Category(s): Technology Classifications > Therapeutics
High-Throughput and Independent Temperature Regulation In Biological Samples
A device that provides independent thermal regulation for biological samples in a 96-well microwell plate. Problem: Thermal control of cellular processes allows for remote control through tissue or opaque media, allowing for precise targeting of therapies in the body as well as broad control of metabolic processes in bioreactors. However, current...
Published: 6/6/2024   |   Inventor(s): Lukasz Bugaj, Brian Chow, William Benman, Zikang (Dennis) Huang
Keywords(s): Bioengineering, Platform Technology
Category(s): Technology Classifications > Hardware & Components, Technology Classifications > Research Tools & Reagents, Technology Classifications > Testing & Measurement
Augmented Reality Interface for Radiation-Free Screw Insertion during Intramedullary Nail Insertion for Long Bone Fractures
The NailedIt Augmented Reality (AR) Surgical Navigation System, comprised of a Windows-based desktop application, augmented reality headsets (HMDs) worn by surgeons, handheld mobile devices supporting remote viewing and surgical site annotation, and spatially tracked medical devices and instruments, assists and guides surgeons while they perform orthopedic...
Published: 4/10/2024   |   Inventor(s): Thomas Schaer, Stephen Lane, Samir Mehta
Keywords(s): Augmented Reality (AR) & Virtual Reality (VR), Orthopedics, Platform Technology, Software, Surgery
Category(s): Technology Classifications > Medical Devices
Biomaterial-Based Vaccine Booster to Enhance Long-Term Immunity (UCLA Case No. 2021-170)
UCLA researchers have developed injectable, cell-free, and biomaterial-based microparticles that can engage with tissue resident immune cells and enhance long-term immunity. It is the first biomaterial-based, targeted approach to induce T memory stem cells (TMSCs) in vivo. The approach was demonstrated for SARS-CoV-2 but can be used for any vaccine....
Published: 2/26/2024   |   Inventor(s): Mohammad Hasani-Sadrabadi, Song Li, Manish Butte
Keywords(s): aAPCs, Aging, artificial presenting cells, cytokines, elderly, immunosenescence, microparticles, platform technology, SARS-CoV-2, T memory stem cells, TMSCs, Vaccines
Category(s): Therapeutics > Infectious Diseases, Therapeutics > Oncology
Ultrasensitive, High-Throughput, Single-Scale Detection of Extracellular Vesicles
An optofluidic platform to detect extracellular vesicles (EVs) at the single-particle level by parallelizing droplet generation and analysis of EVs. Problem: Extracellular vesicles (EVs) are lipid bound nanomaterials carrying various molecular cargo that can be representative of their cells of origin. EVs play a critical role in intercellular communication...
Published: 2/26/2024   |   Inventor(s): David Issadore, Zijian Yang
Keywords(s): Bioengineering, Microfluidics, Optics & Photonics , Platform Technology
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Research Tools & Reagents, Technology Classifications > Testing & Measurement
Human-AI Hybrid Intelligence Model to Accurately Recognize and Segment Organs on Medical Scans 70% Faster Than Physicians
AAR-DL (Automatic Anatomy Recognition – Deep Learning) is a hybrid intelligence recognition and delineation segmentation model that outputs automatically delineated organs in medical images by combining natural intelligence’s (i.e., human knowledge’s) and artificial intelligence's strengths to map organs and their boundaries in...
Published: 6/24/2024   |   Inventor(s): Jayaram Udupa, Tiange Liu, Dewey Odhner, Chao Jin, Yubing Tong, Drew Torigian
Keywords(s): Artificial Intelligence (AI) & Machine Learning, Data Science, Healthcare IT, Oncology, Platform Technology, Radiology, Software
Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Diagnostics, Technology Classifications > Imaging
1 2 3 4