Inteum Company
Links
Visible Legacy
RSS
News & Resources
Inteum Company News
Inteum Library
Subscribe
Search Results - drew+weissman
13
Results
Sort By:
Published Date
Updated Date
Title
ID
Descending
Ascending
Microneedle array coating technology for enhanced stability and targeted delivery of mRNA and biologics
A microneedle-based system uses cryogenically pre-cooled needles coated via thin-film freeze-coating to preserve mRNA stability, enabling efficient, multi-therapeutic intradermal delivery of temperature-sensitive drugs. Background The field of advanced drug delivery systems has grown substantially as the biomedical industry grapples with the complexities...
Published: 1/27/2026
|
Inventor(s):
Zhengrong Cui
,
Michael Sandoval
,
Robert Williams
,
Drew Weissman
,
Qin Li
Keywords(s):
Category(s):
Life sciences > Therapeutics > Drug discovery
Methods and Sequences for mRNA and Other HIV Vaccine Development
Unique sequences eliciting broadly neutralizing antibodies (bNAbs) against human immunodeficiency virus (HIV) that could be used to develop effective mRNA-based and other types of HIV vaccine. Problem: Despite decades of research, there is currently no vaccine to prevent HIV infection. A major goal of HIV vaccine programs is to generate bNAbs, which...
Published: 8/1/2025
|
Inventor(s):
George Shaw
,
Edward (Ted) Kreider
,
Beatrice Hahn
,
Ashwin Skelly
,
Hui Li
,
Drew Weissman
Keywords(s):
Bioengineering
,
HIV/AIDS
,
Immunology
,
Infectious Disease
,
Protein/Peptide (Non-Antibody)
Category(s):
Technology Classifications > Vaccines
Nanoparticles for Precise & Targeted Treatment of Neurological Conditions
Problem: Acute ischemic stroke (AIS) is the second leading cause of death worldwide, affecting around 600,000 Americans annually. However, pharmacological treatment of AIS is difficult due to ineffective and nonspecific targeting to blood brain barrier epitopes via intravenous administration. Over 100 drugs have been tried and failed in clinical trials...
Published: 8/6/2025
|
Inventor(s):
Oscar Marcos Contreras
,
Jacob Brenner
,
Vladimir Muzykantov
,
Jia Nong
,
Patrick Glassman
,
Drew Weissman
,
Sahiley Reyes-Esteves
Keywords(s):
Drug Delivery
,
Inflammation
,
Nanotechnology
,
Neurology
Category(s):
Technology Classifications > Therapeutics
Targeted Organ or Multiple Organ Delivery of mRNA with Ionizable Amphiphilic Janus Dendrimers
A library of easily synthesized ionizable amphiphilic Janus dendrimer (IAJD) compounds that deliver mRNA either to targeted organs or multiple organs, depending on the IAJD design. Problem: Four-component lipid nanoparticles (LNPs) are the benchmark synthetic vector for the delivery of mRNA. Despite their high biosafety, low toxicity, and immunogenicity,...
Published: 9/12/2025
|
Inventor(s):
Virgil Percec
,
Drew Weissman
,
Juncheng (Luke) Lu
,
Elena Atochina-Vasserman
,
Devendra Maurya
,
Dipankar Sahoo
Keywords(s):
Drug Delivery
,
Platform Technology
Category(s):
Technology Classifications > Chemical Processes and Synthesis
,
Technology Classifications > Vaccines
Immune Modulator Encoded Lipid Nanoparticle Formulation Improves T Cell Response to Vaccines
Researchers developed an LNP-mRNA-based vaccine that encodes different cytokine mRNAs, as a method to enhance CD8+ T cell responses and memory formation. Problem: Lipid nanoparticles (LNPs) are an emerging technique to deliver mRNA in vivo more efficiently. While recent progress in mRNA technology has allowed the rapid development of SARS-COV2 vaccines,...
Published: 9/8/2025
|
Inventor(s):
Christopher Hunter
,
Drew Weissman
,
Mohamad-Gabriel Alameh
,
Emily Aunins
,
Anthony Phan
Keywords(s):
Bioengineering
,
Drug Delivery
,
Immunology
,
Immunoncology
,
Immunotherapy
,
Infectious Disease
,
Nanotechnology
Category(s):
Technology Classifications > Therapeutics
,
Technology Classifications > Vaccines
Sunlight-Harvesting Windows for Enhanced Power Generation
Nanoparticle-Embedded Glass Redirects Scattered Light to Solar Cells Within Window Frames that Produce Electricity These sunlight-harvesting windows embedded with metal nanoparticles and framed with photovoltaic cells produce four times as much power as other solar windows. In 2014, the United States installed enough solar photovoltaics to power 4...
Published: 1/20/2026
|
Inventor(s):
Wei Wei
,
Jiangeng Xue
Keywords(s):
Harvesting
,
Infrared Absorption
,
light scattering
,
Nanoparticle
,
Solar Cells
,
Solar Energy
,
Transparent
Category(s):
Technology Classifications > Engineering > Electrical
,
Technology Classifications > Engineering > Materials
Malaria mRNA vaccine
Nearly half of the world's population is at the risk of contracting malaria. According to the World Health Organization, Malaria remains a primary cause of childhood illness and death in sub-Saharan Africa. Recent studies provide evidence of the immunogenicity of mRNA vaccines against Plasmodium falciparum - the parasite responsible for most severe...
Published: 1/9/2026
|
Inventor(s):
Nirbhay Kumar
,
Drew Weissman
,
Clifford Thomas Holeski Hayashi
,
Yi Cao
Keywords(s):
Category(s):
Technology Classifications > Therapeutics > Vaccines
Synthesis of Star-Shaped Gold Nanoparticles for Solar Power and Biomedical Applications
Plasmonic Gold Nanoparticles Improve Photocatalytic Activity in Solar Cells and Windows or Biomedical Sensing This synthesis process produces gold nano-stars, plasmonic nanoparticles useful as photocatalysts for many applications. The gold nanoparticles market is expected to reach $6.33 billion by 2025; the nanoparticles are in large demand to improve...
Published: 1/20/2026
|
Inventor(s):
Wei Wei
,
Wenxiao Guo
Keywords(s):
Category(s):
Technology Classifications > Engineering > Chemical
,
Technology Classifications > Others > Cleantech
Photocatalyst for More Efficient Water Oxidation, CO2 Reduction, and Nitrogen Fixation
Drives Photochemical Reactions Powered by Solar Energy and at Low Temperatures This photocatalyst and photolytic process boosts electrochemical efficiency of common industrial reactions, allowing them to occur under solar conditions and low temperatures. The global photocatalyst market is projected to reach $4.58 billion by 2025. Photocatalysts can...
Published: 1/20/2026
|
Inventor(s):
Wei Wei
Keywords(s):
Category(s):
Technology Classifications > Engineering > Chemical
,
Technology Classifications > Others > Cleantech
Enhanced Au/TiO2 Catalysts for More Efficient O2 Activation
Adjusts Atomic Interface to Enable Catalytic Activity 34 Times Greater Than Traditional Catalysts This enhancement of the Au/TiO2 catalyst results from manipulating its interfacial atomic structures for optimal oxygen activation. Analysts project the global market for catalysts to reach $48 billion in 2027 . The field of heterogeneous catalysis does...
Published: 1/20/2026
|
Inventor(s):
Wei Wei
,
Jiawei Huang
Keywords(s):
Category(s):
Technology Classifications > Others > Others
1
2