Search Results - ophthalmology

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Cutting Needle Holder (Case No. 2024-120)

Intro Sentence: Researchers from the UCLA Jules Stein Eye Institute have developed a novel multi-use surgical instrument for improved oculoplastic surgical outcomes. Background: Oculoplastic surgeries are very common in the United States, with approximately 325,000 blepharoplasties alone performed annually. Suturing during this procedure requires...

Published: 9/11/2024 | Inventor(s): Taras Gout, Erin Napier, Robert Goldberg, Maria Quintero, Ethan Osias, Erica Wilson-Rapolla

Keywords(s): biomedical implantation, Invasiveness Of Surgical Procedures, Medical Device, Medical Devices and Materials, Ophthalmology, Preclinical surgical innovation, Surgical Instrument, surgical mesh, surgical oncology, Surgical Suture , surgical tool, Surgical Tools, wearable medical device, wearable medical devices

Category(s): Medical Devices, Medical Devices > Surgical Tools

System and Methods for Fluidic Control in Ophthalmic Procedures (Case No. 2024-229)

Summary: Researchers in the Mechanical Engineering Department at UCLA developed an innovative mechatronic system that can perform fast and accurate pressure regulation during cataract surgeries. Background: Despite being generally safe and successful, cataract surgery has a complication rate of about 6%, which is concerning given the high volume...

Published: 9/17/2024 | Inventor(s): Tsu-Chin Tsao, Yu-Ting (Kevin) Lai, Aya Barzelay

Keywords(s): biomedical sensors, Intraocular Lens , Ophthalmology, Robotic Surgery

Category(s): Mechanical > Instrumentation, Medical Devices > Hospital Systems, Medical Devices > Surgical Tools, Medical Devices > Monitoring And Recording Systems, Therapeutics > Ophthalmology

Enlarging Attachment for Binocular Indirect Ophthalmoscopy

A retrofittable attachment that provides increased magnification of the back of the eye (the ocular fundus). Background: Indirect ophthalmoscopy is performed by an examiner with the use of a binocular indirect ophthalmoscope (BIO). The examiner uses a headset to view an image of the patient's eye in a condensing lens hand-held by the examiner...

Published: 9/17/2024 | Inventor(s): David Krumholz

Keywords(s): #SUNYresearch, eye examination, fundus, imaging, medical devices, ophthalmology, ophthalmoscopy, retina, Technologies, vision care

Category(s): Technology Classifications > Imaging, Technology Classifications > Medical Devices, Campus > SUNY College of Optometry

Silencing of PRLΔE1 expression: a gene-agnostic treatment for retinal degenerations

Viral vector-mediated gene silencing of a novel short retinal isoform of Prolactin promotes photoreceptor survival. Problem: Age-related macular degeneration (AMD) and inherited retinal degeneration (IRDs) have extreme mutational heterogeneity, and many IRDs are orphan diseases. Developing individual gene therapies for each causative gene is impractical...

Published: 7/2/2024 | Inventor(s): William Beltran, Raghavi Sudharsan

Keywords(s): Drug Target, Gene Therapy, Genetic Disorders, Neurodegenerative Diseases, Ophthalmology, Orphan Disease

Category(s): Technology Classifications > Therapeutics

A Precise, Analytical Model to Measure Visual Function and Monitor Retinal Disease

A model to estimate the change in photoreceptor outer segment length that occurs upon light stimulation – a biomarker of cone function in the retina. Problem: Vision relies on the isomerization of photopigments within photoreceptors (cones and rods) by light. Traditionally, researchers and clinicians have relied on functional assessments of photoreceptor...

Published: 3/6/2024 | Inventor(s): Jessica Morgan, David Brainard, Raymond Warner

Keywords(s): Neurology, Ophthalmology

Category(s): Technology Classifications > Imaging, Technology Classifications > Diagnostics, Technology Classifications > Testing & Measurement

mRNA Therapeutics for Corneal Endothelium Regeneration

A novel mRNA-based therapy that induces corneal endothelium regeneration to restore vision loss Problem: Corneal endothelial cells are critical for maintaining a clear cornea, mainly by pumping fluid out of the tissue. Decrease in number of these cells results in the clouding of the cornea that leads to vision loss. The standard of care for Fuchs Endothelial...

Published: 6/27/2024 | Inventor(s): Panteleimon Rompolas

Keywords(s): Gene Therapy, Healthcare IT, Ophthalmology

Category(s): Technology Classifications > Therapeutics

Assistive Device to Aid in Identification and Use of Medications (UCLA Case No. 2022-213)

Summary: Researchers in the UCLA Stein Eye Institute have developed a medication assistive device to aid in distinguishing medication bottles and administering medications on the correct schedules for patients, especially those with visual impairment. Background: Many ophthalmic conditions are treated with eye drop medications. These treatments...

Published: 10/17/2023 | Inventor(s): Edmund Tsui, Jie Deng, Holly Huang, Jeffrey Li, Hyeongtaek Nam, Brian Wu

Keywords(s): 3D Printing, Hospital Systems And Devices, Medical Devices and Materials, Monitoring And Recording Systems, Ophthalmology, Therapeutics & Vaccines

Category(s): Medical Devices > Monitoring And Recording Systems, Therapeutics > Ophthalmology

Treatment for the Prevention of Permanent Vision Loss in Glaucoma Patients

Problem: Glaucoma is the number one cause of irreversible blindness worldwide. High pressure in the eye can lead to optic nerve damage, which can progress to permanent vision loss. For this reason, reduction of intraocular pressure is the main therapeutic mechanism available. Unfortunately, glaucoma can continue to progress even in patients with normalized...

Published: 1/12/2024 | Inventor(s): Qi Cui, Joshua Dunaief, Jacob Sterling

Keywords(s): Ophthalmology, Small Molecule

Category(s): Technology Classifications > Therapeutics

Simultaneous Crossed And Parallel Polarized Light Viewing/Imaging Through A Split Polarizer

Competitive Advantages Multiple polarization states in a single filter allow for simultaneous surface and sub-surface viewing/imaging of semi-transparent or layer-based materials. This technology eliminates the need to switch or rotate between the states of the polarizer or interact with the device, reducing the need for complex decision-making,...

Published: 9/3/2024 | Inventor(s): Katharine Hanlon-Nielsen

Keywords(s): Forensic Applications, Ophthalmology, Optical, Laser, Fiberoptic, Spectroscopy, Optics and Imaging, Sensors

Thienylpiperidine donor NIR I &II xanthene-based dye for imaging

Overview of Technology NIR Dyes that are highly stable, prepared by short and synthetic routes Background Very few Xanthene-based near-infrared (NIR) photoacoustic (PA) dyes with absorbance greater than 600 nm exist. The few that exist are difficult to access, which require long and tedious synthetic steps. Photoacoustic tomography is a biomedical...

Published: 9/5/2024 | Inventor(s): Chathuranga Rathnamalala, Colleen Scott

Keywords(s): Biomedical, Medical Devices, Military or Defense, Ophthalmology

Category(s): Advanced Materials

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