Search Results - joan+o%27brien

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An Improved and Targeted Approach to Genetic Screening for Primary Open-Angle Glaucoma in African Ancestry Population
A method for more targeted pre-screening for Primary Open-Angle Glaucoma (POAG) in individuals of African ancestry. Problem: POAG, the leading cause of irreversible blindness worldwide, currently affects 44 million individuals globally and is expected to impact 80 million people by the year 2040. Of particular concern is its disproportionate burden...
Published: 10/16/2024   |   Inventor(s): Joan O'Brien, Marylyn Ritchie, Rebecca Salowe, Shefali Verma, Yuki Bradford
Keywords(s): Ophthalmology
Category(s): Technology Classifications > Diagnostics
Differentiation of induced pluripotent stem cells into retinal progenitor cells and mature, functional human retinal ganglion cells
Simplified and reproducible two-step differentiation method optimized for efficient differentiation of human-induced pluripotent stem cells into retinal progenitor cells and functional retinal ganglion cells Problem: More than three million Americans live with glaucoma – a disease that can cause blindness resulting from optic nerve damage....
Published: 2/2/2024   |   Inventor(s): Venkata Chavali, Jason Mills, Joan O'Brien
Keywords(s): Cell Therapy, Ophthalmology, Regenerative Medicine
Category(s): Technology Classifications > Research Tools & Reagents