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Search Results - covid-19
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A Fluorescent Plasmonic Biochip Assay for Multiplex Screening of Diagnostic Serum Antibody Targets in Human Lyme Disease and
COVID-19
A protein microarray, in the form of a compact biochip, that can be analyzed with high sensitivity using GC-FP technology. Background: Some infectious diseases are easy to diagnose, but others are much more difficult. One example is Lyme disease (B. burgdorferi), which is caused by a slow-growing organism that takes many weeks to detect. Current testing...
Published: 4/2/2025
|
Inventor(s):
Nathaniel Cady
Keywords(s):
COVID-19
,
detection
,
diagnostics
Category(s):
Technology Classifications > Diagnostics
,
Campus > SUNY Polytechnic Institute
Intranasal Dantrolene Nanoparticle Use For Treatment Of Alzheimer's Disease
Intranasal delivering of dantrolene nanoparticles could potentially be used to inhibit memory loss and reduce amyloid plaques in patients with Alzheimer's disease. Problem: Alzheimer’s disease (AD) is a devastating neurodegenerative disease. The deficit in the development of new drugs targeting the amyloid pathology over the past several...
Published: 3/12/2025
|
Inventor(s):
Huafeng Wei
,
Qing Cheng Meng
,
Ge Liang
,
Maryellen Eckenhoff
Keywords(s):
Aging
,
COVID-19
,
Nanotechnology
,
Neurodegenerative Diseases
Category(s):
Technology Classifications > Animal Health
,
Technology Classifications > Chemical Processes and Synthesis
,
Technology Classifications > Food Science and Nutrition
,
Technology Classifications > Research Tools & Reagents
,
Technology Classifications > Therapeutics
Rapid Nanomechanical Diagnostic Assay for SARS-CoV-2 and Other Pulmonary Diseases Detection
NU 2021-142 INVENTORS Gajendra Shekhawat* Vinayak Dravid SHORT DESCRIPTION This invention introduces a nanomechanical diagnostic assay leveraging microcantilevers for the rapid and specific detection of SARS-CoV-2 antigens, achieving results in under 10 minutes with high sensitivity and selectivity. BACKGROUND Rapid detection of respiratory...
Published: 3/2/2025
|
Inventor(s):
Keywords(s):
COVID-19
,
Diagnostics
,
Pulmonary disease
,
Research tool
Category(s):
Life Sciences > Biomarkers & Biomedical Research Tools
CRISPR-Mediated Cleavage of Enzyme-Oligonucleotide Conjugates for Detection of Target Analytes
CRISPR-Mediated Cleavage of Enzyme-Oligonucleotide Conjugates for Detection of Target Analytes NU 2021-068 INVENTORS Chad Mirkin* Devleena Samanta Sasha Ebrahimi SHORT DESCRIPTION This technology leverages CRISPR-mediated cleavage of enzyme-oligonucleotide conjugates to enable sensitive, colorimetric detection of target analytes without the...
Published: 3/3/2025
|
Inventor(s):
Keywords(s):
COVID-19
,
Diagnostics
,
Research tool
Category(s):
Life Sciences > Biomarkers & Biomedical Research Tools
High-Throughput Approach to Identify New Lipid Nanoparticle Formulations for Vaccine and Drug Delivery
High-throughput in vivo screening method to identify lipid nanoparticle (LNP) formulations for local and systemic delivery for mRNA vaccines and cancer immunotherapies. Problem: Nucleic acid delivery is an attractive and rapidly growing area of research, particularly for the development of vaccines and cancer immunotherapy. Historically, viral vectors...
Published: 1/7/2025
|
Inventor(s):
Michael Mitchell
,
Alex Hamilton
Keywords(s):
Bioengineering
,
COVID-19
,
Drug Delivery
,
Gene Therapy
,
Immunology
,
Immunoncology
,
Immunotherapy
,
Infectious Disease
,
Nanotechnology
Category(s):
Technology Classifications > Testing & Measurement
,
Technology Classifications > Vaccines
,
Technology Classifications > Therapeutics
Lipid Nanoparticles That Specifically Target The Lungs
Lung-targeting lipid nanoparticles allowing organ specific mRNA delivery for gene therapy applications. Problem: Gene therapy via mRNA delivery allows the rapid generation of therapeutics and vaccines for a wide range of applications. However, mRNA is especially vulnerable to degradation in the body, necessitating packaging within lipid nanoparticles....
Published: 10/17/2024
|
Inventor(s):
Michael Mitchell
,
Lulu Xue
Keywords(s):
Bioengineering
,
COVID-19
,
Gene Therapy
,
Infectious Disease
,
Pulmonary
Category(s):
Technology Classifications > Chemical Processes and Synthesis
,
Technology Classifications > Therapeutics
,
Technology Classifications > Vaccines
Adjuvanted Lipid Nanoparticles (LNPs) Enhance Protective Immunity Imparted by SARS-CoV-2 mRNA Vaccine
A lipid nanoparticle formulation that elicits a strong innate immune response for improved vaccine protection Problem: Lipid nanoparticle (LNP)-formulated mRNA vaccines have revolutionized modern vaccinology through their ability to deliver mRNA vaccines with remarkable manufacturing flexibility. However, the modified (pseudouridylated) mRNA used in...
Published: 10/1/2024
|
Inventor(s):
Michael Mitchell
,
Xuexiang Han
,
Drew Weissman
,
Mohamad Alameh
Keywords(s):
Bioengineering
,
COVID-19
,
Drug Delivery
,
Immunology
,
Infectious Disease
,
Nanotechnology
Category(s):
Technology Classifications > Materials
,
Technology Classifications > Vaccines
Combination Therapy to Treat Viral Acute Respiratory Distress Syndrome (ARDS)
Advantages: PG’s anti-inflammatory effects mitigate viral inflammation of
COVID-19
. Intranasally administered mesenchymal stem cells (MSCs) create an anti-inflammatory microenvironment and can enhance neuro-regenerative effects. Targets viral transmission and neuronal damage to reduce virus-induced neuronal damage, and mortality, and...
Published: 7/15/2024
|
Inventor(s):
Subhra Mohapatra
,
Shyam Mohapatra
,
Mahasweta Das
,
Andrew McGill
,
Karthick Mayilsamy
Keywords(s):
Covid-19
,
Respiratory Diseases Treatment
Category(s):
Technology Classifications > Medical > Respiratory
Low-Cost, Point-of-Care Test for Rapid Visual Diagnosis of
COVID-19
A rapid, low-cost, portable swab-based SARS-CoV-2 biosensor whose test result can be detected with naked eye Problem:
COVID-19
has killed over 2.84 million people worldwide and has disproportionately affected people in lower-income and resource-limited geographies. High-frequency testing can prevent rapid virus spread and reduce COVID-19-related hospitalizations...
Published: 6/26/2024
|
Inventor(s):
Cesar de la Fuente-Nunez
,
Marcelo Der Torossian Torres
,
Lucas Felipe de Lima
,
Andre Lopes Ferreira
Keywords(s):
Bioengineering
,
COVID-19
,
Infectious Disease
Category(s):
Technology Classifications > Diagnostics
,
Technology Classifications > Medical Devices
Targeted Lentiviral Transduction of B-Cells With Desired B-Cell Receptor Specificity (UCLA Case No. 2023-237)
UCLA researchers in the Division of Hematology and Oncology in the Department of Medicine, have discovered novel lentiviral vectors that can be used for gene delivery to B-cells and for the development of neutralizing antibodies against viruses. BACKGROUND: Microbial tropism is a microbiology term that describes the types of animals (including human),...
Published: 2/14/2025
|
Inventor(s):
Koki Morizono
Keywords(s):
B Cell
,
cell receptor
,
COVID-19
,
VIral entry
,
Virus
Category(s):
Therapeutics > Immunology And Immunotherapy
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