Search Results - infectious+diseases

51 Results Sort By:
Methods and Techniques to Classify Stages in the Gonotrophic Cycle of Mosquitoes from Images using Computer Vision Techniques
­Advantages: Enables rapid and accurate identification of mosquito gonotrophic stages, enhancing disease surveillance efforts effectively. Reduces the need for extensive entomological expertise, making mosquito monitoring more accessible and efficient. Facilitates integration with citizen-science platforms, empowering community involvement...
Published: 5/23/2024   |   Inventor(s): Sriram Chellappan, Farhat Azam, Ryan Carney, Sherzod Kariev
Keywords(s): Artificial Intelligence, Infectious Diseases, Predictive Analytics
Category(s): Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Data/AI > D/AI Imaging, Technology Classifications > Computer Science > Algorithms
Use of Dupilumab for Disseminated Fungal Infection (UCLA Case No. 2019-706)
BACKGROUND: Dupilumab, an immunomodulatory drug that blocks IL-4 signaling, is most commonly used to treat moderate-to-severe atopic dermatitis (a form of eczema) and asthma in both adults and adolescents. While fungal infections, such as coccidioidomycosis, can be potentially treated with immunomodulatory drugs, Dupilumab does not currently have...
Published: 5/14/2024   |   Inventor(s): Manish Butte, Maria Garcia-Lloret
Keywords(s): Infectious Diseases, Therapeutics & Vaccines
Category(s): Therapeutics, Therapeutics > Infectious Diseases
Receptor Binding Domain 2 of CDTb Component of the Clostridioides Difficile Binary Toxin CDT as a Vaccine Component Against C. Difficile Infection
­Advantages: Enhanced Vaccine Conservation: This technology ensures the conservation of critical vaccine components across diverse C. difficile strains, improving vaccine effectiveness. Immunogenic Potential: RBD2, a key discovery, exhibits exceptional immunogenicity, promising robust immune responses in vaccine recipients. Inhibition of CDT...
Published: 9/3/2024   |   Inventor(s): Xingmin Sun, Shaohui Wang
Keywords(s): Infectious Diseases, Vaccines
Category(s): Technology Classifications > Medical > Infectious Diseases
Recombinant Fusion Protein Containing Clostridioides Difficile Flagellin Proteins FliC and FliD as a Vaccine Candidate Against C. Difficile Infection
­Advantages: Novel Vaccine Approach: Vacine targeting C. difficile flagellar proteins FliC and FliD. Enhanced Protection: FliCD provides robust immunity, reduces C. difficile infection severity, and decreases spore and toxin levels in feces. Potential Alternative Therapy: Anti-FliCD serum demonstrates promise as an adjunct therapy for CDI,...
Published: 2/13/2024   |   Inventor(s): Xingmin Sun
Keywords(s): Infectious Diseases, Vaccines
Category(s): Technology Classifications > Medical > Infectious Diseases
Exploring Choroid Plexus Senescence as a Potential Link Between COVID-19 and Alzheimer's Disease
­Advantages: Advances viral neurology research by studying SARS-CoV-2's impact on the aging brain's choroid plexus. Identifies potential biomarkers for neurodegenerative diseases through cellular senescence and SASP factor analysis. Informs public health strategies regarding COVID-19-related neurological complications and preventive...
Published: 5/9/2024   |   Inventor(s): Eleni Markoutsa, Shyam Mohapatra, Subhra Mohapatra
Keywords(s): Infectious Diseases, Neurodegenerative Diseases, Therapeutics
Category(s): Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Neuroscience, Technology Classifications > Medical > Therapeutics
Single Domain Antibodies Targeting the S2 Subunit of SARS-CoV-2 Spike Protein
Abstract: The COVID-19 pandemic is a worldwide public health crisis with over 100 million confirmed cases and 2.4 million deaths as of February 2021. COVID-19 is caused by a novel coronavirus called SARS-CoV-2. Almost all the neutralizing antibodies targeting SARS-CoV-2 that are in development recognize the receptor binding domain (RBD) on the spike...
Published: 5/21/2024   |   Inventor(s): Mitchell Ho, Zhijian Duan, Jesse Buffington
Keywords(s): : COVID-19, ANTIBODY, Camel Nanobody, CORONAVIRUS, HO, Infectious Diseases, Nanobodies, Pandemic, SARS-CoV-2, Shark Nanobody, therapeutic, Vaccine
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Immunology, TherapeuticArea > Infectious Disease
Bacteriophage Based-Vaccine System
Abstract: Vaccines have become one of the most important tools in the fight against cancers and infectious diseases. However, some vaccines have shown limitations due to their high cost and low immune responses. To overcome these limitations, bacteriophages were proposed for the development of more cost-effective, immunogenic vaccines. Phages have shown...
Published: 4/8/2024   |   Inventor(s): Sankar Adhya, Donald Court, Xintian Li, Manoj Rajaure
Keywords(s): Adhya, Bacteriophage Engineering, Bacteriophage Genetics, CANCER VACCINE, Infectious Diseases, Lambda Vector, Phage Therapy, Recombineering, Vaccine
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Application > Vaccines
Sensitive and Economic RNA Virus Detection Using a Novel RNA Preparation Method
Abstract: DNA or RNA-based diagnostic tests for infectious diseases are critical in modern medicine. The current gold standard for COVID-19 detection is testing SARS-CoV-2 viral RNA by quantitative reverse transcription Polymerase Chain Reaction (RT-qPCR). This method involves patient sample collection with a nasopharyngeal swab, storage of the swab...
Published: 4/8/2024   |   Inventor(s): Bin Guan, Robert Hufnagel
Keywords(s): Biomarker, Chelating Resin, Chelex Resin, COVID, COVID-19, DNA/RNA diagnostic test, Extraction-free Detection, Infectious Diseases, SARS-CoV-2, virus
Category(s): TherapeuticArea > Oncology, Application > Diagnostics, Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease, Collaboration Sought > Licensing
Therapeutics Against Pathogenic Coronaviruses
Abstract: The COVID-19 pandemic is a worldwide public health crisis with over 440 million confirmed cases and 6.0 million deaths as of March 2022. COVID-19 is caused by a novel coronavirus called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). While there are several vaccines available for COVID-19, there are few therapeutics available...
Published: 4/8/2024   |   Inventor(s): Melvin DePamphilis, Matthew Frieman, Arup Chakraborty
Keywords(s): CORONAVIRUS, COVID-19, Depamphilis, Eunice Kennedy Shriver National Institute of Child Health an, Infectious Diseases, MER-CoV, NICHD, PIKfyve Phosphatidyl Linositol Kinase Inhibitors, SARS-CoV, SARS-CoV-2, virus
Category(s): Application > Therapeutics, Collaboration Sought > Licensing, Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease
Camel VHH Nanobodies Bind the S2 Subunit of SARS-CoV-2 and Broadly Neutralize Variants including Omicron
Abstract: Since its emergence in 2019, COVID-19 infected over 600 million people and over 6 million people have died from the disease. COVID-19 is an infectious disease caused by the SARS-CoV-2 virus. Neutralizing antibodies have been developed to bind to the receptor binding domain (RBD) on the spike (S) protein. Blocking the interaction of the RBD...
Published: 7/29/2024   |   Inventor(s): Mitchell Ho, Jessica Hong, Jesse Buffington, Zhijian Duan
Keywords(s): ANTIBODY, Camel Nanobody, CORONAVIRUS, COVID-19, HO, Infectious Diseases, Nanobodies, Pandemic, SARS-CoV-2, therapeutic, Vaccine
Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Immunology, TherapeuticArea > Infectious Disease, Application > Therapeutics, Collaboration Sought > Licensing
1 2 3 4 5 6