Search Results - blood

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Determining the Donor Age Based on Raman Spectroscopy of a Bloodstain
Novel methodology helps forensic investigators determine victim's age from bloodstains. Background: In the absence of a body at a crime scene, forensic investigators must rely on whatever biological material is left behind to determine the sex, race, and age of perpetrators and victims. That often means analyzing stains like blood, sweat, and...
Published: 9/24/2024   |   Inventor(s): Igor Lednev
Keywords(s): biological, blood, blood based technology, crime scene analysis, DNA, evidence collection, forensic tool, forensics, laboratory blood test, Raman spectroscopy, raman system, spectroscopy, TAF, Technologies, trace evidence
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics
Identification of Body Fluids Using Raman Spectroscopy
A one-step confirmatory test to identify forensic body fluid samples. Technology Overview: This simple, non-destructive method for positive identification of all forensic body fluid types, is based on Raman Spectroscopy,a light scattering phenomenon that provides a unique molecular vibrational signature of a material. The patented technology...
Published: 3/12/2024   |   Inventor(s): Igor Lednev, Kelly Virkler
Keywords(s): 3D printing, blood, evidentiary sample, fluorescence spectroscopy, forensics, oral epithelial cells, Raman microscopy, Raman spectroscopy, saliva, semen, sperm, sweat, TAF, vaginal epithelial cells, vaginal fluid
Category(s): Technology Classifications > Diagnostics, Campus > University at Albany
DNA Methylation Based Non-invasive Blood Diagnostic Assay for Precision Cancer Detection and Classification
This technology includes a panel of 46 genomic loci of DNA methylation (represented by CpG dinucleotides on different chromosomes) with application in blood-based cancer screening. The markers robustly distinguish tumor from normal samples using 8 loci and classify 13 different tumor types. Using 39 loci, inventors were able to discriminate between...
Published: 7/25/2024   |   Inventor(s): Gennady Margolin, Laura Elnitski
Keywords(s): assay, Based, Blood, CANCER, CLASSIFICATION, Detection, diagnostic, DNA, Humans, Methylation, NON-INVASIVE, PRECISION, VCXXXX, WBXXXX, WIXXXX, XEXXXX
Category(s): Application > Research Materials, Application > Diagnostics, TherapeuticArea > Oncology, Application > Therapeutics
Erythroid Progenitor Cell Line for Hematological Disease Applications
Plasmodium vivax (malaria) is a significant health concern in many parts of Asia, Latin America, North Africa, and the Middle East. There is a lack of continuous culture systems for this pathogen. The subject technology is an erythroid progenitor continuous cell line (termed CD36E) identified by erythroid markers CD36, CD33, CD44, CD71, CD235, and...
Published: 7/25/2024   |   Inventor(s): Ning Zhi, Neal Young, Susan Wong
Keywords(s): &, Blod, Blood, CD36E, Cell, Cells, continuous, DDXXXX, DISEASES, DXXXXX, Erythroid, Involving, Line, Malaria, Malaria (Plasmodium sp.), Patent Category - Biotechnology, PLASMODIUM, Potential, PRECURSORS, Progenitor, RED, Spp., STUDIES, termed, USES
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Collaboration Sought > Materials Available, Application > Research Materials, TherapeuticArea > Infectious Disease
A Target for the Development of Diagnostics and Therapeutics for Abnormal Hematopoiesis
The zinc finger protein ZFP36L2 has been shown by the inventors to play an essential role in hematopoiesis, a process that is dysregulated in hematological cancers, anemia, and other conditions. Thus, ZFP36L2 has promise for use in a diagnostic test to detect abnormal hematopoiesis, or as a target for the development of therapeutics to treat abnormal...
Published: 4/8/2024   |   Inventor(s): Deborah Stumpo, Perry Blackshear
Keywords(s): (4)r syndrome, anemia, Blood, C syndrome, CANCER, Chromosome 4 ring syndrome, Chromosome 6 ring syndrome, Chromosome 7 ring syndrome, Chronic myelogenous leukemia, diagnostic, Diagnostic assay, diagnostic test, G syndrome, Hematologic, Hematopoiesis, Hypertelorism with esophageal abnormality and hypospadias, IAXXXX, IBXXXX, IXXXXX, Leukemia, lymphoma, N syndrome, Patent Category - Biotechnology, R(6) syndrome, R(7) syndrome, Syndrome X, therapeutic, Thrombocytopenia 2, Thrombocytopenia chromosome breakage, Tristetraprolin, W syndrome, W syndrome; Syndrome W, ZFP36L2, zinc finger
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, Application > Therapeutics
Nitrite and Nitrite-Methemoglobin Therapy to Detoxify Stroma-Free Hemoglobin Based Blood Substitutes
Cell-free hemoglobin based oxygen carriers (HBOCs) are blood substitutes and resuscitative agents that can be used to replace whole blood donations, alleviate blood shortages and reduce the risks of infections such as HIV and hepatitis. Stroma-free HBOCs offer the advantages of increased stability, consistency of supply, and reduced immunogenicity...
Published: 7/25/2024   |   Inventor(s): Mark Gladwin
Keywords(s): Based, Blood, Detoxify, hemoglobin, Hepatitis A, Hepatitis D, Hepatitis E, ICXXXX, IXXXXX, Nitrite, Nitrite-methemoglobin, Stroma-free, Substitutes, THERAPY
Category(s): Collaboration Sought > Licensing, Application > Therapeutics, Application > Diagnostics, Application > Research Materials
­A TUNABLE PROXIMITY ASSAY THAT CAN OVERCOME DILUTIONAL NON-LINEARITY
­A TUNABLE PROXIMITY ASSAY THAT CAN OVERCOME DILUTIONAL NON-LINEARITY Researchers at Stanford have developed a tunable proximity assay with a wide dynamic range that can detect multiple analytes in a single sample. Blood-based quantification of protein biomarkers is a standard tool for the prediction, diagnosis, and monitoring of disease. Physiological...
Published: 3/17/2023   |   Inventor(s): Hyongsok Soh
Keywords(s): Affinity Reagent, Antibody, Aptamer, Biomolecules, Biosensor System, Blood, Serum
Category(s): Technology Classifications > Biology
CONTINUOUS REAL-TIME MONITORING OF BIOMOLECULES IN LIVE SUBJECTS
­CONTINUOUS REAL-TIME MONITORING OF BIOMOLECULES IN LIVE SUBJECTS Researchers at Stanford have developed methods for the continuous real-time monitoring of biomolecules in live subjects. Real-time biosensors that can continuously measure circulating biomolecules in vivo would revolutionize the healthcare system by enabling truly personalized...
Published: 3/17/2023   |   Inventor(s): Hyongsok Soh, Mahla Poudineh, Jing Pan
Keywords(s): Affinity Reagent, Antibody, Aptamer, Biomolecules, Biosensor System, Blood, Microfluidics
Category(s): Technology Classifications > Engineering
BARCODED CLONAL TRACKING OF GENE TARGETING IN CELLS
BARCODED CLONAL TRACKING OF GENE TARGETING IN CELLS Researchers at Stanford and the Chan Zuckerberg Biohub have developed a methodology to monitor cell expansion and differentiation following targeted genomic modification. Targeted DNA correction of disease-causing mutations offers promise in the treatment of genetic diseases. Following targeted...
Published: 3/17/2023   |   Inventor(s): Daniel Dever, Rajiv Sharma, Matthew Porteus, Ravindra Majeti, Joab Camarena, Thomas Koehnke
Keywords(s): Blood, Cas9, CRISPR, Genome Editing, Genome Integration, Nuclease
Category(s): Technology Classifications > Biology
MULTIPLEXED DETECTION AND CHARACTERIZATION OF MICROBIAL NUCLEIC ACIDS USING SPECTRALLY ENCODED BEADS
MULTIPLEXED DETECTION AND CHARACTERIZATION OF MICROBIAL NUCLEIC ACIDS USING SPECTRALLY ENCODED BEADS Researchers at Stanford and the Chan Zuckerberg Biohub have developed a platform for characterizing a population of microbes using spectrally encoded beads. The clinical treatment of microbial infections is dependent on the proper identification and...
Published: 3/17/2023   |   Inventor(s): Adam White, Huy Nguyen, Feiqiao Yu, Tyler Shimko, Polly Fordyce, Nadya Andini, Samuel Yang
Keywords(s): Blood, Diagnosis, Fluorescence, Microbe, Microfluidics, Nucleic Acid, RNA-seq
Category(s): Technology Classifications > Biology
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