Search Results - epilepsy

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Dissecting Microbiota-Gut-Brain Interactions for the Anti-Seizure Effects of the Ketogenic Diet (UCLA Case No. 2025-006)
UCLA researchers from the Department of Integrative Biology & Physiology have identified specific components of ketogenic diets that alter the microbiome and improve seizure resistance, providing valuable data to optimize diet treatments for refractory epilepsy. BACKGROUND: Refractory epilepsy, a disease characterized by uncontrolled seizures,...
Published: 9/19/2024   |   Inventor(s): Elaine Hsiao
Keywords(s): diet, dietary fiber, Epilepsy, gut, gut-brain axis, ketogenic diet, microbiome, pediatrics, seizure
Category(s): Therapeutics > Gastroenterology, Therapeutics > CNS and Neurology, Therapeutics > Metabolism And Endocrinology
Intelligent, Adaptive, and Multimodal Data-Driven Epileptogenic Zone Identification and Cognitive Function Mapping Platform (UCLA Case No. 2023-214)
Summary: UCLA researchers in the Departments of Neurology and Electrical and Computer Engineering have developed a data-driven, deep learning-powered software platform to localize epileptogenic tissues in the brain and cognitively map nearby regions. Background: According to the World Health Organization, 50 million people around the world suffer...
Published: 8/19/2024   |   Inventor(s): Vwani Roychowdhury, Hiroki Nariai, Richard Staba, Yipeng Zhang
Keywords(s): Artifical Intelligence (Machine Learning, Data Mining), Artificial Intelligence, Artificial Neural Network, Biomonitoring, Brain Mapping, Condition monitoring, Deep Learning, Digital Health, Digital Pathology, Electroencephalography (EEG), Epilepsy, Hospital Systems And Devices, Medical Device, Medical Devices and Materials, Monitoring (Medicine), Monitoring And Recording Systems, MRI, PET, remote monitoring, Software, Software & Algorithms
Category(s): Software & Algorithms, Software & Algorithms > Digital Health, Software & Algorithms > Artificial Intelligence & Machine Learning, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Monitoring And Recording Systems
Passive Wireless Multi-Channel Stimulator
Passive, wireless stimulators have received significant interest due to their ability to provide therapy and rehabilitation by targeting an organ with monophasic or biphasic stimulation pulses. Wireless stimulators are advantageous because they reduce the risk of infection and inflammation by eliminating wires that protrude through the skin. Extending...
Published: 10/7/2024   |   Inventor(s): Jennifer Blain Christen, Shiyi Liu, Ahmed Abed Benbuk, Daniel Gulick
Keywords(s): Brain and Machine Interface, Brain stimulation, Cancer, CNS Therapeutics, Epilepsy, Flexible electronics, Medical Device, Neural implants, Neural Prostheses, Neurostim and Neuromodulation, Neurostimulation, Stimulator, Traumatic Brain Injury
Category(s): Life Science (All LS Techs), Medical Devices
The preparation of a brain targeted artificial nano-enzyme and application
Reference #: 01514 The University of South Carolina is offering licensing opportunities for The preparation of a brain targeted artificial nano-enzyme and application Background: Chronic neuroinflammation is caused by the activation of microglia, which is the major cause of central neuronal system (CNS) diseases, including Alzheimer’s disease,...
Published: 4/25/2024   |   Inventor(s): Peisheng Xu, Haijun Liu
Keywords(s): Alzheimer’s disease, Amyotrophic lateral sclerosis, brain injury, Brain targeted nanoparticle, Brain tumor, Epilepsy, frontotemporal dementia, glioblastoma, Huntington's disease, Multiple sclerosis, neonatal hypoxic-ischemic, neuroblastoma, Parkinson's disease, post-traumatic stress disorder, Spinal cord injury, stroke
Category(s): Nanotechnology, Health Sciences, Biomedical and Life Sciences
A Mouse Model for Mental Disorders and Epilepsy
Current State of the Art The Neuregulin/ErbB4 signaling pathway is involved in GABAergic neurotransmission, an important inhibitory neurotransmission that regulates several processes in the central nervous system including muscle tone. Aberrant GABAergic function has been implicated in Schizophrenia, Schizo-affective disorder and in Epilepsy....
Published: 4/29/2020   |   Inventor(s): Lin Mei, Wen-Cheng Xiong
Keywords(s): Drug Discovery, Drug Testing, Epilepsy, Mouse, Schizophrenia
Category(s): Research Tools
Somatomotor Cortical Mapping for Neurosurgical planning
Epilepsy is one of the most common neurological disorders affecting approximately 65 million people worldwide. Most cases of epilepsy can be controlled through medications, however in about one-third of patients, medication isn’t adequate and surgical resection is considered. In order for surgery to be a viable option, a single localizable focus...
Published: 2/23/2023   |   Inventor(s): Stephen Helms Tillery, Remy Wahnoun
Keywords(s): Electrocorticography, Epilepsy, Tactile
Category(s): Computing & Information Technology, Life Science (All LS Techs), Medical Devices
GlyB4 Fusion with Neuregulin Heparin-Targeting Domain to Block Neuregulin Signaling
We have harnessed this natural targeting ability of NRG by fusing the HBD of NRG to soluble HER4. This fusion protein retains high affinity heparin binding to heparin and to cells that express heparan sulfates resulting in a more potent NRG antagonist. In vivo, it is targeted to peripheral nerve segments where it blocks the activity of NRG as a Schwann...
Published: 12/6/2022   |   Inventor(s): Jeffrey Loeb, Qunfang Lee
Keywords(s): Anti-cancer, Biotechnology, Cancer risk, Cancer Therapies, Drug Delivery, Drug Target, Epilepsy
Category(s): Life Science, Drug Delivery, Other