Search Results - pet

26 Results

Sort By:

Zirconium-89 PET Imaging Agent for Cancer

Abstract: Researchers at the NCI Radiation Oncology Branch and NIH CIT Center for Molecular Modeling developed a tetrahydroxamate chelation technology that provides a more-stable Zr-89 complex as an immuno-PET cancer imaging agent. In either the linear or the macrocyclic form, the tetrahydroxamate complexes exhibit greater stability as chelating agents...

Published: 5/23/2024 | Inventor(s): Francois Guerard, Yong-Sok Lee, Martin Brechbiel

Keywords(s): imaging agent, PET, zirconium-89

Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Application > Research Materials

Intelligent, Adaptive, and Multimodal Data-Driven Epileptogenic Zone Identification and Cognitive Function Mapping Platform (UCLA Case No. 2023-214)

Summary: UCLA researchers in the Departments of Neurology and Electrical and Computer Engineering have developed a data-driven, deep learning-powered software platform to localize epileptogenic tissues in the brain and cognitively map nearby regions. Background: According to the World Health Organization, 50 million people around the world suffer...

Published: 8/19/2024 | Inventor(s): Vwani Roychowdhury, Hiroki Nariai, Richard Staba, Yipeng Zhang

Keywords(s): Artifical Intelligence (Machine Learning, Data Mining), Artificial Intelligence, Artificial Neural Network, Biomonitoring, Brain Mapping, Condition monitoring, Deep Learning, Digital Health, Digital Pathology, Electroencephalography (EEG), Epilepsy, Hospital Systems And Devices, Medical Device, Medical Devices and Materials, Monitoring (Medicine), Monitoring And Recording Systems, MRI, PET, remote monitoring, Software, Software & Algorithms

Category(s): Software & Algorithms, Software & Algorithms > Digital Health, Software & Algorithms > Artificial Intelligence & Machine Learning, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Monitoring And Recording Systems

A Novel Reagent for Labeling PET Tracers at Trifluoromethyl Groups

The molecular imaging technique of positron emission tomography (PET) is an increasingly important tool in biomedical research and in drug discovery and development. Many small molecule drugs and potential PET radiotracers carry trifluoromethyl (CF3) groups. Because CF3 groups are generally considered to be metabolically stable, there is a strong interest...

Published: 7/25/2024 | Inventor(s): Mohammad Haskali, Victor Pike

Keywords(s): :, [11C]Fluoroalkanes, Added, AGENT, LABELING, Method, No-Carrier, PET, Producing, Radiotracers, VAXXXX, VCXXXX, VDXXXX, VEXXXX, VNXXXX, WBXXXX, WIXXXX, XDXXXX, XFXXXX, YAXXXX, YBXXXX, YFXXXX

Category(s): Collaboration Sought > Collaboration, Application > Diagnostics, Application > Research Materials, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Geriatrics, Application > Software / Apps, TherapeuticArea > Psychiatry/Mental Health, TherapeuticArea > Neurology, Application > Medical Devices, TherapeuticArea > Immunology

Evans Blue Dye Derivatives for Serum Albumin Labeling

The invention is an imaging agent and method of use for imaging blood pools and the lymphatic system. The imaging agent binds with high affinity to serum albumin, the most abundant serum protein, and can be tagged with several isotopes making it suitable for magnetic resonance imaging or positron emission tomographic imaging. To date, only very few...

Published: 7/25/2024 | Inventor(s): Lixin Lang, Gang NIU, Xiaoyuan (Shawn) Chen

Keywords(s): Albumin, BLUE, CA2BXX, Evans Blue, fluorene-18, IA4AXX, LABELED, LABELING, Listed LPM Fenn as of 4/15/2015, Magnetic Resonance, PET, Pet imaging, positron emission, Positron-Emitting, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, PXXXXX

Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Oncology, Application > Consumer Products, Application > Diagnostics, Application > Research Materials

Small Molecule Imaging of Fungi by Positron Emission Tomography Scanning

This technology relates to the field of radioactive, isotopically-labeled calcofluor derivatives and uses of such compounds to detect a broad spectrum of filamentous fungi including pathogenic species such as Aspergillus and Mucorales, by diagnostic imaging methods such as positron emission tomography (PET) scanning. Aspergillosis and other filamentous...

Published: 7/25/2024 | Inventor(s): Dale Kiesewetter, John Panepinto, Jin Qiu, Peter Williamson

Keywords(s): DA1XXX, FUNGI, IMAGING, Listed LPM Fenn as of 4/15/2015, MOLECULE, PET, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, SCANNING, Small, VKXXXX, WBXXXX, XFXXXX, YCXXXX

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease, Application > Medical Devices, Application > Software / Apps, Application > Diagnostics, Application > Non-Medical Devices

Photoinduced Electron Transfer Fluorescent Primer for Nucleic Acid Amplification

CDC scientists have developed a rapid and cost-efficient method for generating fluorescently labeled primers for PCR and real-time PCR. At present, fluorescent primers are useful for detecting and identifying microbes and specific nucleic acid sequences, amplifying nucleic acids for pyro-sequencing, determining the levels of gene expression, and many...

Published: 7/25/2024 | Inventor(s): Vincent Hill, Brian Holloway, Jothikumar Narayanan

Keywords(s): AA2XXX, AA5XXX, AAXXXX, AC4XXX, AC5XXX, AC6XXX, Acid, ACXXXX, AE1BXX, AG1XXX, amplification, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, ELECTRON, Nucleic, OID-NCEZID-DFWED, PET, PHOTOINDUCED, PRIMER, TRANSFER, VAXXXX, VBXXXX, VCXXXX, VDXXXX, VEXXXX, VGXXXX, VHXXXX, VIXXXX, VJXXXX, VKXXXX, VLXXXX, VMXXXX, VNXXXX, VOXXXX, VPXXXX, WAXXXX, WBXXXX, WCXXXX, WFXXXX, WGXXXX, WHXXXX, WIXXXX, WMXXXX, XBXXXX, XCXXXX, XEXXXX, XHXXXX, YBXXXX

2021-144 BIOMARKERS OF DRUG TARGET ENGAGEMENT IN CANCER

UCLA researchers in the Department of Molecular and Medical Pharmacology have identified kinase inhibitors that block glucose consumption and for which [18F]FDG PET can be used as a biomarker, potentially aiding in the early assessment of therapeutic regimen and faster clinical trials.BACKGROUND: Pharmacodynamic biomarkers of drug efficacy...

Published: 9/5/2023 | Inventor(s): Peter Clark, Chiara Ghezzi

Keywords(s): Diagnostic Markers & Platforms, PET

Category(s): Life Science Research Tools > Screening Libraries, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Medical Devices > Medical Imaging > PET, Therapeutics > Oncology

2020-163 POSITRON EMISSION TOMOGRAPHY GUIDED DELIVERY OF MITOCHONDRIAL COMPLEX I INHIBITORS

UCLA researchers in the David Geffen School of Medicine Division of Pulmonary and Critical Care Medicine have developed a novel use of the positron emission tomography (PET) tracer [18F]FBnTP to guide the delivery of mitochondrial complex I inhibitors for the treatment of lung cancers.BACKGROUND: The mitochondria are essential regulators of cellular...

Published: 7/19/2023 | Inventor(s): David Shackelford, Saman Sadeghi, Milica Momcilovic

Keywords(s): Diagnostic Markers & Platforms, Imaging, Medical Imaging, PET, Respiratory & Pulmonary

Category(s): Medical Devices > Medical Imaging > PET, Therapeutics > Oncology, Therapeutics > Respiratory And Pulmonary

2019-231: Radiotracer for Synaptic Imaging

UCLA researchers in the Department of Neurology have synthesized a novel radiotracer that selectively identifies functional synapses for monitoring of synaptic loss in Alzheimer’s patients. BACKGROUND: Alzheimer’s disease (AD) is a debilitating neurodegenerative disorder that cannot be prevented, cured or slowed. It affects more than 17...

Published: 7/19/2023 | Inventor(s): Varghese John, Mohammad Parvez Alam, Asa Hatami, Daniel Silverman, Saman Sadeghi

Keywords(s): Cns, Diagnostic Markers & Platforms, Medical Imaging, PET

Category(s): Medical Devices > Medical Imaging > PET

Development and Applications of Multi-modality Engineered Antibody Fragments as New

INTRO SENTENCE:UCLA researchers in the Department of Molecular and Medical Pharmacology have developed a method that allows the dual labeling of antibodies with an optical dye and an 18F radionuclide for multi-modality imaging.BACKGROUND:Multi-modality antibody-based imaging represents an important advance in the medical field, since it can combine...

Published: 7/19/2023 | Inventor(s):

Keywords(s): Animal Imaging, Fluorescence, Life Science Research Tools, Medical Imaging, PET

Category(s): Life Science Research Tools > Animal Imaging, Life Science Research Tools, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > PET, Medical Devices > Medical Imaging > Fluorescence

1 2 3