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Search Results - microbiome
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Dissecting Microbiota-Gut-Brain Interactions for the Anti-Seizure Effects of the Ketogenic Diet (UCLA Case No. 2025-006)
UCLA researchers from the Department of Integrative Biology & Physiology have identified specific components of ketogenic diets that alter the
microbiome
and improve seizure resistance, providing valuable data to optimize diet treatments for refractory epilepsy. BACKGROUND: Refractory epilepsy, a disease characterized by uncontrolled seizures,...
Published: 9/19/2024
|
Inventor(s):
Elaine Hsiao
Keywords(s):
diet
,
dietary fiber
,
Epilepsy
,
gut
,
gut-brain axis
,
ketogenic diet
,
microbiome
,
pediatrics
,
seizure
Category(s):
Therapeutics > Gastroenterology
,
Therapeutics > CNS and Neurology
,
Therapeutics > Metabolism And Endocrinology
Nisin-Based Formulations for Oral and Systemic Conditions (UCLA Case Nos. 2023-133 and 2022-306)
UCLA researchers in the Department of Dentistry have found a novel use for nisin alone, and in formulations, for use in the treatment of Alzheimer’s disease, and multiple inflammation states such as brain inflammation, joint inflammation, oral inflammation, systemic inflammation, inflammatory bowel diseases, and non-alcoholic fatty liver disease...
Published: 9/19/2024
|
Inventor(s):
Yvonne Kapila
Keywords(s):
Alzheimers disease
,
Antibacterial
,
gut inflammation
,
Inflammation
,
microbiome
,
nanoparticle delivery system
,
Nanoparticles
,
nisin
,
oral inflammation
,
periodontal disease
,
periodontal inflammation
,
periodontal regeneration
Category(s):
Therapeutics > CNS and Neurology
Antimicrobial Peptides (AMPs) Mined from Human Gut Metagenome Are Effective Against Antibiotic Resistant Pathogens
The collective genomes of the human gut
microbiome
, known as the metagenome, encode peptides that are effective against antibiotic-resistant bacteria. Problem: Antimicrobial resistance poses a major threat to public health. The development of drug-resistance outpaces traditional drug discovery approaches. As a result, the supply of drugs available to...
Published: 6/26/2024
|
Inventor(s):
Cesar de la Fuente-Nunez
,
Marcelo Der Torossian Torres
,
Ami Bhatt
,
Erin Brooks
Keywords(s):
Artificial Intelligence (AI) & Machine Learning
,
Bioengineering
,
Infectious Disease
,
Microbiome
,
Protein/Peptide (Non-Antibody)
Category(s):
Technology Classifications > Computer Information Systems
,
Technology Classifications > Therapeutics
New Postbiotics for Skin Health
Advantages: Developed unique strains of postbiotics that offer a safer alternative to live probiotics for improving overall skin health. Enhanced wound healing effects in animal studies Strains can go into any formulation for skin health or cosmetics, e.g. body wash, soap, shampoo, oils, cream etc.. Summary: The escalating issue of slow...
Published: 5/16/2024
|
Inventor(s):
Hariom Yadav
,
Shalini Jain
,
Santosh Prajapati
,
Atul Chander
Keywords(s):
Microbiome
,
Wound and Tissue Healing
Category(s):
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical > Biotechnology
Microbiome
Based Precision Nutrition Model
Advantages: By identifying suitable diets that enhance beneficial bacteria and metabolic activities, the research can potentially help individuals address gut-related issues and reduce conditions like leaky gut and inflammation. By understanding the unique composition of the gut microbiota and its response to different dietary factors, personalized...
Published: 9/25/2023
|
Inventor(s):
Hariom Yadav
,
Shalini Jain
Keywords(s):
Gastrointestinal / Digestive Health
,
Microbiome
Category(s):
Technology Classifications > Medical > Cell & Tissue Engineering
,
Technology Classifications > Medical
,
Technology Classifications > Medical > Neuroscience
Lung
Microbiome
Isolation and Cultivation
Competitive Advantages: Novel method to isolate, cultivate, and amplify the lung
microbiome
from a limited resource Beneficial for testing antibiotic sensitivity and drug resistance Enables lung microbiome transplantation for treatment of various chronic lung diseases Summary: Chronic lung diseases such as asthma, COPD, cystic fibrosis,...
Published: 9/3/2024
|
Inventor(s):
Andreas Seyfang
,
Nirmal Sharma
Keywords(s):
Cancer Treatment Lung Cancer
,
Health Tech
,
Microbiome
Category(s):
Technology Classifications > Medical > Respiratory