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Search Results - pediatrics
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Non-invasive Pain Measurement of Infants and Toddlers Using Acoustic Features of Cries (Copyright; Case No. 2018-327)
Summary: Researchers in the UCLA Semel Institute for Neuroscience and Human Behavior have developed a novel, non-invasive pain measurement tool for neonates. Background: Pain management in neonatal care remains a critical unmet need. Approximately 90% of premature infants undergo painful procedures, yet pain is only reported in 45% of cases. Current...
Published: 4/9/2025
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Inventor(s):
Ariana Anderson
Keywords(s):
acoustics
,
artificial intelligence/machine learning models
,
Digital Signal Processing
,
Machine Learning Pain Management
,
Monitoring (Medicine)
,
non-invasive monitoring
,
Pain Treatment
,
pediatrics
Category(s):
Diagnostic Markers >
Pediatrics
,
Medical Devices > Monitoring And Recording Systems
,
Platforms > Diagnostic Platform Technologies
,
Software & Algorithms > Artificial Intelligence & Machine Learning
,
Software & Algorithms > AI Algorithms
,
Software & Algorithms > Data Analytics
,
Software & Algorithms > Digital Health
,
Therapeutics > Critical Care
,
Therapeutics > Psychiatry And Mental Health
Dissecting Microbiota-Gut-Brain Interactions for the Anti-Seizure Effects of the Ketogenic Diet (UCLA Case No. 2025-006)
UCLA researchers from the Department of Integrative Biology & Physiology have identified specific components of ketogenic diets that alter the microbiome and improve seizure resistance, providing valuable data to optimize diet treatments for refractory epilepsy. BACKGROUND: Refractory epilepsy, a disease characterized by uncontrolled seizures,...
Published: 2/14/2025
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Inventor(s):
Elaine Hsiao
Keywords(s):
diet
,
dietary fiber
,
Epilepsy
,
gut
,
gut-brain axis
,
ketogenic diet
,
microbiome
,
pediatrics
,
seizure
Category(s):
Therapeutics > Gastroenterology
,
Therapeutics > CNS and Neurology
,
Therapeutics > Metabolism And Endocrinology
Questionnaires for Assessing the Effect of Visual Impairment on Quality of Life and Function in Children
Application A standardized series of questions for the assessment of vision related quality of life and visual function in children and adolescents. Key Benefits Provides age-appropriate questions for children from ages 8-18 as an improvement to using currently available assessments geared toward adults. Allows the subjective assessment of the...
Published: 2/13/2025
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Inventor(s):
Sheila Angeles-Han
Keywords(s):
Ophthalmology Treatments
,
Pediatrics
,
Surveys and Screening Tools
Category(s):
TechPub Algolia > Research Tools
Drug Platform for L-Asparaginases for the Treatment of Leukemias
Application A novel humanized therapeutic L-asparaginase compound to treat acute lymphoblastic leukemia (ALL) and other cancers. Key Benefits A novel drug discovery platform for developing asparaginase-based compounds to treat leukemias and other cancers. The derivatives could exhibit less immunogenicity and systemic toxicity than FDA-approved...
Published: 3/28/2025
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Inventor(s):
Sunil Raikar
,
Christopher Doering
,
H. (Harold) Trent Spencer
,
Kristopher Knight
,
Harrison Brown
Keywords(s):
Oncology Treatments
,
Pediatrics
,
Platform
Category(s):
TechPub Algolia > Drug Discovery
RSV Vaccine for Infants and Children
Application Vaccine for Respiratory Syncytial Virus (RSV) in infants and children. Key Benefits A novel vaccine targeting both the F and G proteins of the respiratory syncytial virus (RSV), including its variants. Preliminary data in in mice show the vaccine induced the production of antibodies associated with preventing disease. Potential to...
Published: 2/13/2025
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Inventor(s):
Larry Anderson
,
Binh Ha
,
Heying Sun
Keywords(s):
Microbiology and Infectious Disease Treatments
,
Pediatrics
,
Respiratory Treatments
Category(s):
TechPub Algolia > Vaccines
Non-invasive Probes to Determine Efficacy of Cancer Therapies
Application A real-time, non-invasive probe to determine the efficacy of cancer immunotherapies. Key Benefits Determines immunotherapy success in patients. CAR cells can be tested before putting it back in the patients. Simple diagnostic with readout in 30 minutes compared to 2-3 days. Market Summary Lymphoblastic leukemia is one of the most...
Published: 3/28/2025
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Inventor(s):
Anna Kellner
,
Khalid Salaita
,
Curtis Henry
Keywords(s):
Oncology Treatments
,
Pediatrics
Category(s):
TechPub Algolia > Diagnostics
Improving Pediatric Asthma Management for Urban Families
Application Home-based family psychoeducational intervention for low-income children with persistent asthma. Key Benefits Medical and psychosocial needs of patients and family members can be addressed simultaneously. Significantly improved asthma management and caregiver stress in randomized controlled clinical trial. Market Summary Asthma...
Published: 2/13/2025
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Inventor(s):
Marianne Celano
,
Lisa Kobrynski
,
Chanda Holsey
Keywords(s):
Healthcare Professional Education and Training
,
Immunology and Inflammation Treatments
,
Pediatrics
,
Respiratory Treatments
Category(s):
TechPub Algolia > Therapeutics
Engineered Biomaterials for Vascular Grafts
Application A biomaterial to create grafts for treating babies with congenital heart diseases. Key Benefits A biocompatible material that can be used to reroute blood within the body. Experimental data in animals show the material is biocompatible with no clots, thrombus, or adverse immune reactions. Potential to be used in other cardiovascular...
Published: 2/13/2025
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Inventor(s):
Saimuralidhar (Murali) Padala
,
Jahnavi Mudigonda
Keywords(s):
Biomaterials
,
Cardiology and Vascular Devices
,
Pediatrics
Category(s):
TechPub Algolia > Non-Therapeutics
Central Line-Associated Bloodstream Infection (CLABSI) Prediction Model
Application A predictive model of central line-association bloodstream infection (CLABSI). Key Benefits Specifically designed to improved predictive analysis of patients who are at risk for CLABSI. Scored higher predictive values on average than similar predictive modeling without the hypotheses driven approach (Bidirectional LSTM with...
Published: 2/13/2025
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Inventor(s):
Azade Tabaie
,
Rishikesan (Rishi) Kamaleswaran
,
Evan Orenstein
Keywords(s):
Hematology and Blood Products
,
Hospital and Surgical Assistance
,
Pediatrics
Category(s):
TechPub Algolia > Non-Therapeutics
Microfluidic and Organotypic Tumor Slice Culture Drug Testing Platform for Individualized Cancer Therapy
Application A drug combination screening/testing platform for individualized cancer therapy. Key Benefits Rapid screening of effective drug combination. Integrated tumor microenvironment. Identifying personalized therapy for individual cancer patient. Market Summary Traditional two-dimensional (2D) in vitro culture models for drug development...
Published: 2/13/2025
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Inventor(s):
Tobey John MacDonald
,
Anna Kenney
,
Abhinav Dey
,
YongTae (Tony) Kim
Keywords(s):
Microfluidics
,
Pediatrics
,
Platform
Category(s):
TechPub Algolia > Drug Discovery
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