Search Results - mri

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Method and Apparatus for Segmentation of Dense MR Images Using Deep Learning with Domain Adaptation (Case No. 2025-208)
Summary: UCLA researchers from the Department of Radiological Sciences have developed a deep learning-based segmentation framework that enables fully automated and reproducible analysis of left ventricular (LV) function in Displacement Encoding with Stimulated Echoes (DENSE) MRI. Background: Myocardial strain is a key metric for analyzing how much...
Published: 8/18/2025   |   Inventor(s): Xiaodong Zhong, Siyue Li, Kim-Lien Nguyen
Keywords(s): acute myocardial infarction, adjustable mount, aneurysm drainage, automatic leveling, bedside decisions, blood pressure monitoring, cardiac cycle, Cardiac Electrophysiology, Cardiac failure, Cardiac Magnetic Resonance Imaging, Cardiac MRI, Cardiovascular, Cardiovascular Disease, Cardiovascular Disease Nephropathy, cardiovascular diseases, cardiovascular monitoring, cerebrospinal fluid (CSF) drainage, Cine MRI, clamp, critical-care, CSF drainage, Deep learning MRI, DENSE MRI, laser alignment, Left ventricular segmentation, lumbar drains, Motion analysis, MRI, multiparametric MRI (mpMRI), Myocardial strain, non-invasive cardiac monitoring, operator variability, passive reflective target, phlebostatic axis measurement, Pseudo-labeling, radial MRI, Segment Anything Model (SAM), self-leveling system, transducer alignment, Unsupervised domain adaptation (UDA)
Category(s): Medical Devices > Cardiac, Electrical > Imaging, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Image Processing, Therapeutics > Cardiovascular, Therapeutics > Radiology, Medical Devices > Medical Imaging > MRI, Medical Devices > Medical Imaging
Biocatalytic production of MRI contrast agents
Executive Summary Herpes simplex virus type-1 thymidine kinase (HSV1-TK) is an enzyme that phosphorylates a wide range of nucleoside analogs, and has been used as a reporter gene with a variety of radiolabeled nucleotide analogs for positron emission tomography (PET). However, the complexity of synthesizing radiolabel probes and their short lifetime,...
Published: 8/5/2025   |   Inventor(s): Aimen Al-Hilfi, Assaf Gilad
Keywords(s): Medical Imaging, MRI
Category(s): Medical, Chemicals
A Denoising Technique for Multi-Contrast Multi-Coil Magnetic Resonance Imaging (Case No. 2024-233)
Summary: UCLA researchers in the Department of Radiological Sciences have developed a novel MRI denoising technique that enhances image clarity, sensitivity, and precision by significantly reducing distortion and noise. Background: Magnetic resonance imaging (MRI) is critical for medical diagnosis, but image quality depends on achieving a high signal-to-noise...
Published: 7/2/2025   |   Inventor(s): Holden Wu, Shu-Fu Shih, Zhaohuan Zhang
Keywords(s): Cardiac Magnetic Resonance Imaging, Image Processing, Magnetic Resonance Imaging, Magnetic Resonance Imaging Carotid Artery Stenosis, Magnetic Resonance Imaging Hypoxia (Medical), Magnetic Resonance Imaging Medical Physics, Magnetic Resonance Imaging Pathology, Medical Device, medical device cardiac monitoring, Medical Devices and Materials, Medical diagnostics, Medical Imaging, MRI, multi-contrast imaging, Signal-To-Noise Ratio
Category(s): Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Monitoring And Recording Systems, Medical Devices > Medical Imaging > MRI
A Dynamic and Adaptive Approach for Resolving Motion (Case No. 2024-250)
Summary: UCLA researchers in the Department of Radiology have developed a novel method to capture time-varying and irregular cardiac motion, producing high-precision, high-quality cine images. Background: Cine MRI is a specialized imaging technique that captures motion through a series of images, often used to evaluate cardiac function and morphology....
Published: 4/21/2025   |   Inventor(s): Zhengyang Ming, Dan Ruan, Anthony Christodoulou, Kim-Lien Nguyen
Keywords(s): arrhythmia, Biomonitoring, Cardiac Magnetic Resonance Imaging, cardiovascular diseases, cardiovascular monitoring, Image Resolution, Imaging, Magnetic Resonance Imaging, Medical Device, medical device cardiac monitoring, Medical Imaging, Monitoring And Recording Systems, MRI, non-invasive cardiac monitoring, optimization
Category(s): Medical Devices, Medical Devices > Cardiac, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Medical Devices > Monitoring And Recording Systems
Interleaved Radial Amine CEST and Sodium (INTERLACED) NMR Pulse Sequence (Case No. 2024-069)
Summary: UCLA researchers in the Department of Radiological Sciences have developed a novel MRI modality that simultaneously utilizes multiple nuclei to enhance scanning capabilities while reducing scanning times. Background: Magnetic Resonance Imaging (MRI) is a major tool in medical diagnostics and monitoring, as well as the primary clinical research...
Published: 2/25/2025   |   Inventor(s): Benjamin Ellingson, Alfredo Lopez Kolkovsky
Keywords(s): diagnostic radionuclides, Functional Magnetic Resonance Imaging, Magnetic Resonance Imaging, MRI, multiparametric MRI (mpMRI)
Category(s): Medical Devices, Medical Devices > Medical Imaging
Compounds for Improved Psychological and Resilience Measures Associated with Physical Activity (UCLA Case No. 2022-272)
UCLA researchers from the Department of Medicine have identified microbiome and metabolic markers associated with high physical activity in an obese population, leading to possible therapies that may provide the positive effects of physical activity. BACKGROUND: It is known that physical activity has a multitude of beneficial effects on health. On...
Published: 7/17/2025   |   Inventor(s): Arpana Church
Keywords(s): Bacteria, Exercise, Gastroenterology & Digestive Disease, gut-brain axis, Human Gastrointestinal Tract, metabolomics, microbiome, MRI, Nutraceuticals / Probiotics, obesity, physical activity, prebiotics, Psychology
Category(s): Therapeutics > Gastroenterology, Therapeutics > Psychiatry And Mental Health, Therapeutics > Metabolism And Endocrinology
Needle Guide and Holder for Percutaneous Access to Subcutaneous and Deep Tissue Targets (Case No. 2024-207)
Summary: UCLA researchers in the Department of Interventional Radiology have developed a device to secure a needle during image-guided, minimally-invasive procedures, mitigating unwanted migration between scans. Background: Minimally invasive procedures in medicine are becoming increasingly popular, taking the place of traditional open surgeries....
Published: 6/24/2025   |   Inventor(s): David Lu
Keywords(s): CT, image-guided surgery, intervention, Medical Device, MRI, Radiology, Surgery
Category(s): Medical Devices > Surgical Tools
A Method and System for Pre-processing Medical Images (Case No. 2024-177)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a novel pre-processing computer algorithm for automated medical imaging. Background: The integration of machine learning and artificial intelligence into medical imaging applications offers significant potential to automate the diagnosis of various...
Published: 2/14/2025   |   Inventor(s): Bahram Jalali, Callen MacPhee, Yiming Zhou, Koichiro Kishima
Keywords(s): 3D ultrasound imaging, Artificial Intelligence, bioimaging, Computer Vision, histopathology images, Machine Learning, Medical Imaging, MRI, X-Ray
Category(s): Diagnostic Markers > Cancer, Diagnostic Markers > Immunology, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Digital Health, Software & Algorithms > Image Processing
A Deep-Learning Framework for Quantitative Magnetic Resonance Imaging (Case No. 2021-268)
Summary: Researchers from UCLA’s Departments of Bioengineering and Radiological Sciences have developed a novel deep learning framework for accelerated quantitative magnetic resonance imaging. Background: Fatty liver disease, or hepatic steatosis, affects nearly 2 billion people globally and has pernicious implications for deadlier diseases...
Published: 7/17/2025   |   Inventor(s): Holden Wu, Shu-Fu Shih
Keywords(s): Deep Learning, fat quantification, IIM framework, Imaging, Medical Imaging, Metabolic/Endocrinology, MRI, multiparametric MRI (mpMRI), radial MRI, uncertainty estimation
Category(s): Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Electrical, Electrical > Imaging, Software & Algorithms
Time Efficient Multi-Pulsed Field Gradient (mPFG) MRI Without Concomitant Gradient Field Artifacts
Abstract: Measuring and mapping nervous tissue microstructure noninvasively is a long sought-after goal in neuroscience. Clinically, several neuropathologies such as cancer and stroke, are associated with changes in tissue microstructure. Diffusion tensor imaging (DTI), which models diffusion anisotropy, is an ideal imaging modality to elucidate these...
Published: 4/22/2025   |   Inventor(s): Peter Basser, Michal Komlosh, Magdoom Mohamed Kulam Najmudeen
Keywords(s): Basser, Diffusion Tensor Distribution MR Imaging, DTI, Eunice Kennedy Shriver National Institute of Child Health an, Komlosh, Magnetic Resonance Imaging, mPFG, MRI, Multi-Pulsed Field Gradient, Najmudeen, NICHD
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Application > Diagnostics, TherapeuticArea > Immunology
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