Search Results - mri

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A Method and System for Pre-processing Medical Images (Case No. 2024-177)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a novel pre-processing computer algorithm for automated medical imaging. Background: The integration of machine learning and artificial intelligence into medical imaging applications offers significant potential to automate the diagnosis of various...
Published: 7/23/2024   |   Inventor(s): Bahram Jalali, Callen MacPhee, Yiming Zhou, Koichiro Kishima
Keywords(s): 3D ultrasound imaging, Artificial Intelligence, bioimaging, Computer Vision, histopathology images, Machine Learning, Medical Imaging, MRI, X-Ray
Category(s): Diagnostic Markers > Cancer, Diagnostic Markers > Immunology, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Digital Health, Software & Algorithms > Image Processing
A Deep-Learning Framework for Quantitative Magnetic Resonance Imaging (Case No. 2021-268)
Summary: Researchers from UCLA’s Departments of Bioengineering and Radiological Sciences have developed a novel deep learning framework for accelerated quantitative magnetic resonance imaging. Background: Fatty liver disease, or hepatic steatosis, affects nearly 2 billion people globally and has pernicious implications for deadlier diseases...
Published: 8/8/2024   |   Inventor(s): Holden Wu, Shu-Fu Shih
Keywords(s): Deep Learning, fat quantification, IIM framework, Imaging, Medical Imaging, Metabolic/Endocrinology, MRI, multiparametric MRI (mpMRI), radial MRI, uncertainty estimation
Category(s): Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Electrical, Electrical > Imaging, Software & Algorithms
Time Efficient Multi-Pulsed Field Gradient (mPFG) MRI Without Concomitant Gradient Field Artifacts
Abstract: Measuring and mapping nervous tissue microstructure noninvasively is a long sought-after goal in neuroscience. Clinically, several neuropathologies such as cancer and stroke, are associated with changes in tissue microstructure. Diffusion tensor imaging (DTI), which models diffusion anisotropy, is an ideal imaging modality to elucidate these...
Published: 4/8/2024   |   Inventor(s): Peter Basser, Michal Komlosh, Magdoom Mohamed Kulam Najmudeen
Keywords(s): Basser, Diffusion Tensor Distribution MR Imaging, DTI, Eunice Kennedy Shriver National Institute of Child Health an, Komlosh, Magnetic Resonance Imaging, mPFG, MRI, Multi-Pulsed Field Gradient, Najmudeen, NICHD
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Application > Diagnostics, TherapeuticArea > Immunology
Denoising of Dynamic Magnetic Resonance Spectroscopic Imaging Using Low Rank Approximations in the Kinetic Domain
Abstract: Accurate measurement of low metabolite concentrations produced by medically important enzymes is commonly obscured by noise during magnetic resonance imaging (MRI). Measuring the turnover rate of low-level metabolites can directly quantify the activity of enzymes of interest, including possible drug targets in cancer and other diseases. Noise...
Published: 4/8/2024   |   Inventor(s): Jeffery Brender, Kazutoshi Yamamoto, Jeeva Munasinghe, Shun Kishimoto, Hellmut Merkle, Murali Cherukuri, James Mitchell
Keywords(s): 13C imaging, Brender, Denoising, DNP, Dynamic Nuclear Polarization, Glucose Metabolism, Low Metabolite Concentration, Magnetic Resonance Imaging, Metabolic Enzymes, MRI, Software Plugin, SPECTROSCOPIC
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Software / Apps, TherapeuticArea > Oncology
Tamperless Tensor Elastography Imaging
Abstract: Measuring and mapping nervous tissue microstructure noninvasively is a long sought-after goal in neuroscience. Several neuropathologies – such as cancer and stroke – are associated with changes in tissue microstructure. Changes in material properties, such as stiffness, represent a sensitive measure of underlying changes in tissue architecture,...
Published: 4/8/2024   |   Inventor(s): Peter Basser, Magdoom Mohamed Kulam Najmudeen
Keywords(s): Alzheimer’s Disease, Anisotropy, Basse, brain, CANCER, Elasticity Tensor, Elastography, Eunice Kennedy Shriver National Institute of Child Health an, Magnetic Resonance Imaging, MRI, Najmudeen, NICHD, TBI, TRAUMA, Traumatic Brain Injury
Category(s): TherapeuticArea > Neurology, Application > Diagnostics, TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing
MRI-Based Method for Characterizing Axonal Microstructure in Traumatic Brain Injury
Abstract: Neurites of the central nervous system can be conceptualized as cylindrical pores with finite lengths and radii. In response to physical trauma, axons may assume a “beaded” morphology which alters their ability to conduct electrical impulses, impairing brain function. These microstructural changes are thought to underlie some of the cognitive...
Published: 4/8/2024   |   Inventor(s): Peter Basser, Dan Benjamini, Michal Komlosh
Keywords(s): Magnetic Resonance Imaging, MRI, MRI diagnostic, Neurites, Peripheral Nervous System, PNS, TBI, Traumatic Brain Injury
Category(s): Application > Diagnostics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Neurology
Methods of Determining Homeostatic Perturbations
Abstract: Biological homeostasis is a state of steady internal, physical, and chemical conditions maintained by a living organism observed at the cellular level.  Biological homeostasis can vary in order to alter the cellular physical and chemical conditions. Thus, it acts as a mechanism to define the physiological state of cellular activity; for instance...
Published: 4/8/2024   |   Inventor(s): Rea Ravin, Nathan Williamson, Teddy Cai, Peter Basser
Keywords(s): Basser, Biomarkers, Central Nervous System, CNS, functional imaging, HOMEOSTASIS, Magnetic Resonance Imaging, MRI, NICHD, NMR, Nuclear Magnetic Resonance, r, Steady-state, The Eunice Kennedy Shriver National Institute of Child Healt
Category(s): TherapeuticArea > Oncology, TherapeuticArea > Neurology, Application > Diagnostics, Collaboration Sought > Licensing
MADCO-Accelerated Multidimensional Diffusion MRI
Abstract: Although multidimensional diffusion/relaxation NMR experiments are widely used in materials sciences and engineering applications, preclinical and clinical MRI applications of these techniques were not feasible. Moreover, higher-field MRI scanners posed another obstacle to translation of this NMR method. Their specific absorption rate (SAR)...
Published: 4/8/2024   |   Inventor(s): Peter Basser, Dan Benjamini
Keywords(s): Basser, Biomarkers, Diffusion MRI, IMAGING, Marginal-Distributions, MRI, MRI diagnostic, Multidimensional-NMR, NMR-Spectroscopy, Relaxometry Diffusometry, T1, T2
Category(s): TherapeuticArea > Oncology, Collaboration Sought > Collaboration, TherapeuticArea > Immunology, Collaboration Sought > Licensing, Collaboration Sought > Materials Available, Application > Diagnostics
Quantitative In Vivo Methods for Measuring Brain Networks
Abstract: The pattern or latency connectome was hypothesized to change in physiological development and disease.  For example, in amyotrophic lateral sclerosis (ALS), large diameter axons are damaged selectively – while in autism, small-diameter axons may be over-expressed. These anatomical changes are expected to alter the latency connectome or pattern...
Published: 4/8/2024   |   Inventor(s): Peter Basser
Keywords(s): Axon diameter distribution, connectome, DTI Tractography, Magnetic Resonance Imaging, MRI, MRI diagnostic
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, Application > Diagnostics
Multidimensional MRI Signature for Specific Detection of Traumatic Brain Injury In Vivo
Abstract: Traumatic brain injury (TBI) represents a major medical, social and economic concern worldwide due to significant mortality – especially among younger populations – and long-term disabilities. Various pathological brain lesions (e.g., intracerebral bleedings, necrotic-ischemic lesions, tissue avulsion) are produced by impacting mechanical...
Published: 4/8/2024   |   Inventor(s): Dan Benjamini, Peter Basser, Diego Iacono
Keywords(s): Amyloid Precursor Protein, Be, DAI, Diffuse Axonal Injury, Eunice Kennedy Shriver National Institute of Child Health an, Magnetic Resonance Imaging, MRI, MULTIDIMENSIONAL, NICHD, TAI, TBI, Traumatic Axonal Injury, Traumatic Brain Injury
Category(s): TherapeuticArea > Neurology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics
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