Search Results - mri

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A Dynamic and Adaptive Approach for Resolving Motion (Case No. 2024-250)
Summary: UCLA researchers in the Department of Radiology have developed a novel method to capture time-varying and irregular cardiac motion, producing high-precision, high-quality cine images. Background: Cine MRI is a specialized imaging technique that captures motion through a series of images, often used to evaluate cardiac function and morphology....
Published: 12/20/2024   |   Inventor(s): Zhengyang Ming, Dan Ruan, Anthony Christodoulou, Kim-Lien Nguyen
Keywords(s): arrhythmia, Biomonitoring, Cardiac Magnetic Resonance Imaging, cardiovascular diseases, cardiovascular monitoring, Image Resolution, Imaging, Magnetic Resonance Imaging, Medical Device, medical device cardiac monitoring, Medical Imaging, Monitoring And Recording Systems, MRI, non-invasive cardiac monitoring, optimization
Category(s): Medical Devices, Medical Devices > Cardiac, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Medical Devices > Monitoring And Recording Systems
Interleaved Radial Amine CEST and Sodium (INTERLACED) NMR Pulse Sequence (Case No. 2024-069)
Summary: UCLA researchers in the Department of Radiological Sciences have developed a novel MRI modality that simultaneously utilizes multiple nuclei to enhance scanning capabilities while reducing scanning times. Background: Magnetic Resonance Imaging (MRI) is a major tool in medical diagnostics and monitoring, as well as the primary clinical research...
Published: 11/19/2024   |   Inventor(s): Benjamin Ellingson, Alfredo Kolkovsky
Keywords(s): diagnostic radionuclides, Functional Magnetic Resonance Imaging, Magnetic Resonance Imaging, MRI, multiparametric MRI (mpMRI)
Category(s): Medical Devices, Medical Devices > Medical Imaging
Compounds for Improved Psychological and Resilience Measures Associated with Physical Activity (UCLA Case No. 2022-272)
UCLA researchers from the Department of Medicine have identified microbiome and metabolic markers associated with high physical activity in an obese population, leading to possible therapies that may provide the positive effects of physical activity. BACKGROUND: It is known that physical activity has a multitude of beneficial effects on health. On...
Published: 11/18/2024   |   Inventor(s): Arpana Church
Keywords(s): Bacteria, Exercise, Gastroenterology & Digestive Disease, gut-brain axis, Human Gastrointestinal Tract, metabolomics, microbiome, MRI, Nutraceuticals / Probiotics, obesity, physical activity, prebiotics, Psychology
Category(s): Therapeutics > Gastroenterology, Therapeutics > Psychiatry And Mental Health, Therapeutics > Metabolism And Endocrinology
Needle Guide and Holder for Percutaneous Access to Subcutaneous and Deep Tissue Targets (Case No. 2024-207)
Summary: UCLA researchers in the Department of Interventional Radiology have developed a device to secure a needle during image-guided, minimally-invasive procedures, mitigating unwanted migration between scans. Background: Minimally invasive procedures in medicine are becoming increasingly popular, taking the place of traditional open surgeries....
Published: 10/25/2024   |   Inventor(s): David Lu
Keywords(s): CT, image-guided surgery, intervention, Medical Device, MRI, Radiology, Surgery
Category(s): Medical Devices > Surgical Tools
A Method and System for Pre-processing Medical Images (Case No. 2024-177)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a novel pre-processing computer algorithm for automated medical imaging. Background: The integration of machine learning and artificial intelligence into medical imaging applications offers significant potential to automate the diagnosis of various...
Published: 12/10/2024   |   Inventor(s): Bahram Jalali, Callen MacPhee, Yiming Zhou, Koichiro Kishima
Keywords(s): 3D ultrasound imaging, Artificial Intelligence, bioimaging, Computer Vision, histopathology images, Machine Learning, Medical Imaging, MRI, X-Ray
Category(s): Diagnostic Markers > Cancer, Diagnostic Markers > Immunology, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Digital Health, Software & Algorithms > Image Processing
A Deep-Learning Framework for Quantitative Magnetic Resonance Imaging (Case No. 2021-268)
Summary: Researchers from UCLA’s Departments of Bioengineering and Radiological Sciences have developed a novel deep learning framework for accelerated quantitative magnetic resonance imaging. Background: Fatty liver disease, or hepatic steatosis, affects nearly 2 billion people globally and has pernicious implications for deadlier diseases...
Published: 8/8/2024   |   Inventor(s): Holden Wu, Shu-Fu Shih
Keywords(s): Deep Learning, fat quantification, IIM framework, Imaging, Medical Imaging, Metabolic/Endocrinology, MRI, multiparametric MRI (mpMRI), radial MRI, uncertainty estimation
Category(s): Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Electrical, Electrical > Imaging, Software & Algorithms
Time Efficient Multi-Pulsed Field Gradient (mPFG) MRI Without Concomitant Gradient Field Artifacts
Abstract: Measuring and mapping nervous tissue microstructure noninvasively is a long sought-after goal in neuroscience. Clinically, several neuropathologies such as cancer and stroke, are associated with changes in tissue microstructure. Diffusion tensor imaging (DTI), which models diffusion anisotropy, is an ideal imaging modality to elucidate these...
Published: 12/6/2024   |   Inventor(s): Peter Basser, Michal Komlosh, Magdoom Mohamed Kulam Najmudeen
Keywords(s): Basser, Diffusion Tensor Distribution MR Imaging, DTI, Eunice Kennedy Shriver National Institute of Child Health an, Komlosh, Magnetic Resonance Imaging, mPFG, MRI, Multi-Pulsed Field Gradient, Najmudeen, NICHD
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Application > Diagnostics, TherapeuticArea > Immunology
Denoising of Dynamic Magnetic Resonance Spectroscopic Imaging Using Low Rank Approximations in the Kinetic Domain
Abstract: Accurate measurement of low metabolite concentrations produced by medically important enzymes is commonly obscured by noise during magnetic resonance imaging (MRI). Measuring the turnover rate of low-level metabolites can directly quantify the activity of enzymes of interest, including possible drug targets in cancer and other diseases. Noise...
Published: 4/8/2024   |   Inventor(s): Jeffery Brender, Kazutoshi Yamamoto, Jeeva Munasinghe, Shun Kishimoto, Hellmut Merkle, Murali Cherukuri, James Mitchell
Keywords(s): 13C imaging, Brender, Denoising, DNP, Dynamic Nuclear Polarization, Glucose Metabolism, Low Metabolite Concentration, Magnetic Resonance Imaging, Metabolic Enzymes, MRI, Software Plugin, SPECTROSCOPIC
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Software / Apps, TherapeuticArea > Oncology
Tamperless Tensor Elastography Imaging
Abstract: Measuring and mapping nervous tissue microstructure noninvasively is a long sought-after goal in neuroscience. Several neuropathologies – such as cancer and stroke – are associated with changes in tissue microstructure. Changes in material properties, such as stiffness, represent a sensitive measure of underlying changes in tissue architecture,...
Published: 4/8/2024   |   Inventor(s): Peter Basser, Magdoom Mohamed Kulam Najmudeen
Keywords(s): Alzheimer’s Disease, Anisotropy, Basse, brain, CANCER, Elasticity Tensor, Elastography, Eunice Kennedy Shriver National Institute of Child Health an, Magnetic Resonance Imaging, MRI, Najmudeen, NICHD, TBI, TRAUMA, Traumatic Brain Injury
Category(s): TherapeuticArea > Neurology, Application > Diagnostics, TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing
MRI-Based Method for Characterizing Axonal Microstructure in Traumatic Brain Injury
Abstract: Neurites of the central nervous system can be conceptualized as cylindrical pores with finite lengths and radii. In response to physical trauma, axons may assume a “beaded” morphology which alters their ability to conduct electrical impulses, impairing brain function. These microstructural changes are thought to underlie some of the cognitive...
Published: 4/8/2024   |   Inventor(s): Peter Basser, Dan Benjamini, Michal Komlosh
Keywords(s): Magnetic Resonance Imaging, MRI, MRI diagnostic, Neurites, Peripheral Nervous System, PNS, TBI, Traumatic Brain Injury
Category(s): Application > Diagnostics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Neurology
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