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Reagent Molding Process for Point of Care Microfluidic Applications

Invention Description Lyophilization is a critical process for stabilizing reagents in point-of-care (POC) diagnostics, effectively eliminating the need for cold chain storage and preventing liquid evaporation. While this technology is essential for developing robust field-deployable devices, current industry standards are limited to producing reagents...

Published: 1/26/2026 | Inventor(s): Jennifer Blain Christen, Vi Nguyen

Keywords(s):

Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Point of Care

User-Actuated Valve Actuator for Microfluidic Devices

Invention Description Lab-on-a-chip technology and microfluidic diagnostic devices often rely on complex mechanical or electrical systems to manipulate fluid, making them costly and bulky. These components may limit portability, decrease operational lifetime, and prevent widespread use by untrained personnel or patients at the point of care or at home....

Published: 1/12/2026 | Inventor(s): Clifford Anderson, Vi Nguyen, Jennifer Blain Christen

Keywords(s): Analytical Devices, Bioassay, Biosensor, Fluid, Micro-Fluidics

Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Point of Care

Integrated Microfluid Cartridge for POC Biofluid Diagnostics

Invention Description Rapid and reliable nucleic acid assays are critical for diagnosing infectious diseases at the point of need, yet most systems rely on complex, expensive instrumentation and trained personnel. These requirements limit access to timely diagnostics in low-resource, remote, or decentralized settings. Many platforms typically require...

Published: 1/6/2026 | Inventor(s): Vi Nguyen, Clifford Anderson, Jennifer Blain Christen

Keywords(s):

Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Coronavirus, COVID-19, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Point of Care, SARS-CoV-2

Microfluidic Device Design for Point-of-Care Devices

Implementing liquid-based assays, such as PCR and LAMP, is difficult in POC microfluidic devices, due to bubble formation. To mitigate this, auxiliary metering systems or actuators are required to regulate consistent flow rates. This can make the microfluidic device more complicated to operate, increases cost, and limits rapid prototyping, ultimately...

Published: 9/29/2025 | Inventor(s): Vi Nguyen, Jennifer Blain Christen

Keywords(s):

Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Manufacturing/Construction/Mechanical, Medical Diagnostics/Sensors, Genomic Assays/Reagents/Tools

Flexible Optical Biosensor for Point of Care Multi-Biomarker Detection

Fluorescence based point-of-care molecular diagnostic systems are ubiquitous in healthcare. However, many tests require that the sample be sent to a reference laboratory and read by trained medical staff which can be expensive and result in delayed analysis. Portable systems have been developed, however, detecting multiple biomarkers requires a different...

Published: 8/27/2025 | Inventor(s): Joseph Smith, Jennifer Blain Christen, Karen Anderson, Benjamin Katchman

Keywords(s): Bioanalysis, Flexible electronics, Fluorescence

Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Chemical/Biological Sensors, Diagnostic Assays/Devices, Life Science (All LS Techs), Point of Care

Sweat as a Biofluid for Analysis and Disease Identification

Noninvasive sampling is critical for certain patient populations, such as hemophiliacs, neonates, elderly or immunocompromised individuals, especially if they require daily monitoring. Blood sampling is painful, inconvenient and often difficult and increases the risk of exposure to infectious agents, which can be devastating to immunocompromised populations....

Published: 8/27/2025 | Inventor(s): Benjamin Katchman, Karen Anderson, Jennifer Blain Christen

Keywords(s): Antibiotic Resistant Bacteria, Antibodies, Autoantibody, biomarker, Defense/military, Diagnostics, Sweat

Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools

Wildfire Monitoring System for Real-Time Risk Assessment

Background The increasing frequency and severity of wildfires creates difficulty for power engineers to decide on the best course of action for ensuring reliable and resilient system operation. To enable informed decision-making in the presence of active wildfire risks, knowledge of the local environmental conditions surrounding the electric power...

Published: 10/2/2025 | Inventor(s): Jennifer Blain Christen, Anamitra Pal, Randy Essikpe, Umit Ogras, Line Roald, Elisabeth Graffy

Keywords(s):

Category(s): Physical Science, Applied Technologies, Environmental, Wireless & Networking

System for At-Home Monitoring of Pressure and Flow Characteristics associated with Biomechanical Implants

There are numerous medical issues which are treated with simple biomechanical implants that regulate fluid pressure and flow (e.g. valves and shunts). Because there are moving parts to these implants, they are vulnerable to complications, malfunctions and biological/mechanical/parametric failures. Currently, the only way to determine if a biomechanical...

Published: 2/13/2025 | Inventor(s): Jennifer Blain Christen, Daniel Gulick, Sule Ozev

Keywords(s):

Category(s): Life Science (All LS Techs), Medical Devices, Computing & Information Technology

Passive Wireless Multi-Channel Stimulator

Passive, wireless stimulators have received significant interest due to their ability to provide therapy and rehabilitation by targeting an organ with monophasic or biphasic stimulation pulses. Wireless stimulators are advantageous because they reduce the risk of infection and inflammation by eliminating wires that protrude through the skin. Extending...

Published: 2/13/2025 | Inventor(s): Jennifer Blain Christen, Shiyi Liu, Ahmed Abed Benbuk, Daniel Gulick

Keywords(s): Brain and Machine Interface, Brain stimulation, Cancer, CNS Therapeutics, Epilepsy, Flexible electronics, Medical Device, Neural implants, Neural Prostheses, Neurostim and Neuromodulation, Neurostimulation, Stimulator, Traumatic Brain Injury

Category(s): Life Science (All LS Techs), Medical Devices

Self-Powered Fishing Net Lighting Modules for Bycatch Reduction

Background Small-scale fisheries cumulatively account for about half of the production of the fishing industry. These coastal fisheries commonly use gillnets, which are low cost, high yield, and easy to maintain. Unfortunately, gillnets result in considerable non-target species (bycatch) mortality which can negatively impact local ecology and fishing...

Published: 2/13/2025 | Inventor(s): Mark Bailly, Jesse Senko, Jennifer Blain Christen, Michael Goryll, Stuart Bowden, Christopher Lue Sang

Keywords(s):

Category(s): Physical Science, Agriculture/Animal Health, Environmental

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