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Search Results - computing+%26+information+technology
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Method for Repurposing FDA-approved Therapeutics & Composition for Treating Mesothelioma
The amount of time and money that goes into getting a drug from initial discovery to FDA approval is substantial, typically involving at least 10 years and hundreds of millions of dollars. Because of this, there has been a growing interest in repurposing drugs which have previously been approved for human use, particularly since their MOA as well as...
Published: 1/7/2025
|
Inventor(s):
Chris Plaisier
,
Sierra Wilferd
,
Choung Hoang
Keywords(s):
Cancer
,
Drug
,
Drug Discovery
Category(s):
Pharmaceuticals
,
Cancer
,
Cancer Therapeutics
,
Artificial Intelligence/Machine Learning
,
Computing & Information Technology
,
Life Science (All LS Techs)
Precision Medicine for Psychedelic Therapies
Stress related psychiatric disorders (SRPDs) such as post-traumatic stress disorder (PTSD), major depressive disorder (MDD), mood disorders, psychotic disorders, anxiety disorders, substance use disorders (SUDs) and more, are a leading disease burden worldwide with increasing diagnoses among adolescents as well as adults. They are influenced by both...
Published: 12/11/2024
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Inventor(s):
Candace Lewis
Keywords(s):
Category(s):
Life Science (All LS Techs)
,
Non-Cancer Therapeutics
,
Pharmaceuticals
,
Computing & Information Technology
,
Artificial Intelligence/Machine Learning
Weight-Agnostic Federated Neural Architecture Search
Federated learning (FL) is envisaged to be a promising solution for collaboratively training a machine learning model while keeping the training data decentralized and private. For example, in FL, different participants might have different samples of data from different classes. Some participants might have no samples from some of the subclasses...
Published: 10/29/2024
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Inventor(s):
Rida Bazzi
,
Om Thakkar
Keywords(s):
Algorithm Development
,
Machine Learning
,
PS-Computing and Information Technology
Category(s):
Computing & Information Technology
,
Physical Science
,
Artificial Intelligence/Machine Learning
Cyber-Physical Interaction Aware Test Case Generation to Identify Operational Changes
Present day autonomous systems are cyber-physical systems (CPS) that involve multi-dimensional interaction between the cyber machine and the operational environment. One of the key aspects of these autonomous systems is that interaction patterns change over the lifetime of usage. Changes in CPS interaction patterns can be unintentional or intentional...
Published: 10/28/2024
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Inventor(s):
Sandeep Gupta
,
Aranyak Maity
,
Ayan Banerjee
,
Imane Lamrani
Keywords(s):
Algorithm Development
,
Inspection
,
Machine Learning
,
PS-Computing and Information Technology
,
Test
Category(s):
Computing & Information Technology
,
Physical Science
,
Artificial Intelligence/Machine Learning
High Fidelity Fast Simulation of Human in the Loop Human in the Plant (HIL-HIP) Systems
Background Current Level 3 Autonomous systems such as Tesla FSD or Hybrid Closed Loop systems such as Medtronic 770 have both humans in charge of key decisions as well as are part of the system leading to critical need for new modeling and simulation techniques which takes into account this unique characteristics of these systems: Human in the Loop...
Published: 9/26/2024
|
Inventor(s):
Ayan Banerjee
,
Sandeep Gupta
Keywords(s):
Category(s):
Wireless & Networking
,
Computing & Information Technology
,
Applied Technologies
,
Physical Science
Vital Signs Monitoring using Depth Cameras
Cardiovascular disease is responsible for an estimated 17.9 million deaths each year, making it the leading cause of death worldwide. Continuous heart health monitoring way is the best preventative for heart failure. However, standard monitoring devices, including ECG and PPG, require direct physical contact, which can be difficult for certain patient...
Published: 10/22/2024
|
Inventor(s):
Yu Rong
,
Daniel Bliss
Keywords(s):
Category(s):
Computing & Information Technology
,
Medical Devices
,
Life Science (All LS Techs)
,
Medical Diagnostics/Sensors
,
Medical Imaging
Self-Identifying Active Relay
5G wireless systems are designed to meet the increasing demand for high data rates but face challenges like signal obstruction, poor penetration, high propagation loss, and inadequate scattering. Active relays have emerged as a solution to these issues by re-routing signals to avoid obstructions, ensuring uninterrupted 5G service. However, in dense...
Published: 8/30/2024
|
Inventor(s):
Subhan Zakir
,
Saeed Zeinolabedinzadeh
,
Waleed Ahmad
Keywords(s):
Communications Systems
,
Networks, IT, Software and Communication
,
PS-Computing and Information Technology
,
Signal Processing
,
Wireless
Category(s):
Computing & Information Technology
,
Physical Science
Independent Audit and Assessment Framework for AI Systems
AI systems are increasingly being used in critical applications where safety and reliability are paramount such as health care, autonomous driving, and financial services. Numerous AI systems operate as “black boxes,” meaning a system that processes inputs and produces outputs without revealing how it reaches its conclusions. This makes...
Published: 9/19/2024
|
Inventor(s):
Siddharth Srivastava
,
Pulkit Verma
Keywords(s):
Algorithm Development
,
Artificial Intelligence
,
Machine Learning
,
PS-Computing and Information Technology
,
Risk Assessment
Category(s):
Computing & Information Technology
,
Physical Science
Mapping Targets of Antibody Binding
The use of monoclonal antibodies (mAbs) in research, diagnostics and therapeutics is ubiquitous, particularly because of their ability to simultaneously achieve high affinity and specificity. mAbs binding typically involves interactions between it and 5-8 amino acids in a specific spatial arrangement. These interactions at defined positions is what...
Published: 8/13/2024
|
Inventor(s):
Neal Woodbury
,
Laimonas Kelbauskas
,
Akanksha Singh
,
Pritha Bisarad
Keywords(s):
Category(s):
Applied Technologies
,
Bioanalytical Assays, Chemistries & Devices
,
Computing & Information Technology
,
Life Science (All LS Techs)
,
Proteomic Assays/Reagents/Tools
,
Pharmaceuticals
Enhancing Fairness Through Aleatoric Uncertainty
Background In recent years, advancements in machine learning have revolutionized various domains, but concerns about bias and unfairness in automated decision-making systems have gained significant attention. One of the causes of unfairness in AI systems is the reliance on training data. Aleatoric uncertainty refers to the inherent randomness or variability...
Published: 8/7/2024
|
Inventor(s):
Anique Tahir
,
Lu Cheng
,
Huan Liu
Keywords(s):
Artificial Intelligence
,
Machine Learning
Category(s):
Physical Science
,
Computing & Information Technology
,
Intelligence & Security
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