Search Results - amyotrophic+lateral+sclerosis

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Drug Candidate for ALS
RNA aptamers that focus on glutamate receptors are a potential drug candidate for amyotrophic lateral sclerosis (ALS). Background: Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease, is a progressive neuromuscular disease for which there is no cure. The disease attacks motor neurons that run from the brain to the spinal cord...
Published: 1/29/2024   |   Inventor(s): Li Niu, Zhen Huang
Keywords(s): ALS, amyotrophic lateral sclerosis, aptamers, drug design, Lou Gehrig's disease, MND, motor neurone disease, RNA
Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > University at Albany
Caspase Inhibitors Useful for the Study of Autoimmune or Inflammatory Diseases
Novel and potent caspase 1 inhibitors are available for licensing. In particular, this technology discloses potent and selective caspase 1 inhibitors that target the active site of the enzyme. Caspase 1 is known to play a pro-inflammatory role in numerous autoimmune and inflammatory diseases and therefore represents an excellent target for treatment...
Published: 10/28/2024   |   Inventor(s): Matthew Boxer, Craig Thomas
Keywords(s): 1, Amyotrophic lateral sclerosis, Amyotrophic lateral sclerosis 1; Amyotrophic lateral scleros, Amyotrophic lateral sclerosis 6, Caspase, IB3XXX, IBXXXX, Inflammatory bowel disease 1, inhibitor, IXXXXX, Lou Gehrig's disease, Patent Category - Chemistry
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, Application > Therapeutics, TherapeuticArea > Immunology
The preparation of a brain targeted artificial nano-enzyme and application
Reference #: 01514 The University of South Carolina is offering licensing opportunities for The preparation of a brain targeted artificial nano-enzyme and application Background: Chronic neuroinflammation is caused by the activation of microglia, which is the major cause of central neuronal system (CNS) diseases, including Alzheimer’s disease,...
Published: 4/25/2024   |   Inventor(s): Peisheng Xu, Haijun Liu
Keywords(s): Alzheimer’s disease, Amyotrophic lateral sclerosis, brain injury, Brain targeted nanoparticle, Brain tumor, Epilepsy, frontotemporal dementia, glioblastoma, Huntington's disease, Multiple sclerosis, neonatal hypoxic-ischemic, neuroblastoma, Parkinson's disease, post-traumatic stress disorder, Spinal cord injury, stroke
Category(s): Nanotechnology, Health Sciences, Biomedical and Life Sciences