Search Results - yibo+zhang

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Conditional FKBP51 Over-expression Transgenic Mouse

Advantages: Created a transgenic mice model that allows researchers to precisely control the expression of human FKBP51. Offers a tailored approach to studying psychiatric disorders, enabling the development of personalized treatments. Enhances the understanding of the molecular mechanisms underlying psychiatric disorders such as depression,...

Published: 9/3/2024 | Inventor(s): Chad Dickey(VA) (DECEASED - See Notes), Laura Blair, Bo Zhang

Keywords(s): Animal Models, Psychiatry / Mental Health

Category(s): Technology Classifications > Research Tools/Copyright > Animal Models, Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Neuroscience, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Therapeutics

Targeted Therapy for Triple-Negative Breast Cancer

Breast cancer is the second leading cause of death in women and is the most common cancer among women worldwide. There are four main breast cancer subtypes, luminal A, luminal B, HER2-positive and triple-negative. Triple-negative breast cancer (TNBC) is highly invasive and has higher rates of metastasis and a worse prognosis. Metastasis of cancer cells...

Published: 9/12/2023 | Inventor(s): Shengxi Chen, Xiaojiang Cui, Yi Zhang, Sidney Hecht

Keywords(s):

Category(s): Life Science (All LS Techs), Advanced Materials/Nanotechnology, Cancer, Cancer Therapeutics, Pharmaceuticals

Photonic FPGA platform to create arbitrary photonic devices by programming the device structure into the platform.

Background The development and design process for electronic integrated circuits is very intensive before a finalized chip design is sent to the chip fab. Most application-specific electronic integrated circuits require a prototyping process that can be accomplished with a field-programmable gate array (FPGA), an electronic circuit which can be reconfigured...

Published: 5/7/2024 | Inventor(s): Jaime Cardenas Gonzalez, Yi Zhang, Marissa Granados-Baez

Keywords(s):

Category(s): Nanotechnology

Imaging Inflammation using PET Radioligands that Target Translocator Protein 18?kDa with High Affinity Regardless of Genotype

This technology includes a group of radioligands that label inflammatory cells specifically, accurately, and across different genotypes and can be detected using Positron Emission Tomography (PET). The radioligands target the Translocator protein 18 kDa (TSPO) receptor which is present on the outer mitochondrial membrane and is involved in the production...

Published: 7/25/2024 | Inventor(s): Robert Innis, Federico Da Settimo, Giorgio Stefancich, Sabrina Taliani, Sabrina Castellano, Claudia Martini, Yi Zhang, Victor Pike

Keywords(s): 18kDa, Emission, Genotype, Human, Listed LPM Fenn as of 4/15/2015, NA1XXX, Positron, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Quantifying/imaging, Radioligands, Regardless, tomography, TSPO, VEXXXX, VNXXXX, WBXXXX, WIXXXX, XCXXXX, XFXXXX

Category(s): TherapeuticArea > Psychiatry/Mental Health, Application > Non-Medical Devices, TherapeuticArea > Neurology, Application > Software / Apps, Application > Diagnostics, Application > Medical Devices, Application > Research Materials

Neutralizing Antibodies to Influenza HA and Their Use and Identification

The effectiveness of current influenza vaccines varies by strain and season, in part because influenza viruses continuously evolve to evade human immune responses. While the majority of seasonal influenza infections cause relatively mild symptoms, each year influenza virus infections result in over 500,000 hospitalizations in the United States and Europe....

Published: 7/25/2024 | Inventor(s): Robert Bailer, Michael Joyce, John Mascola, Peter Kwong, Sarah Andrews, Paul Thomas, Gwo-Yu Chuang, Adam Wheatley, Yi Zhang, James Whittle, Adrian McDermott

Keywords(s): 1, 2, antibodies, DB4XXX, DBXXXX, DC5XXX, DCXXXX, DXXXXX, GROUP, INFLUENZA, Neutralize, That, Their, Viruses, VLXXXX, WJXXXX, WNXXXX, XAXXXX, XKXXXX, YCXXXX

Category(s): Collaboration Sought > Licensing, Application > Therapeutics, Application > Vaccines, TherapeuticArea > Infectious Disease, ResearchProducts > Antibodies, TherapeuticArea > Immunology

2014-9AG Wide-Field Computational Imaging of Pathology Slides Using Lensfree On-Chip Microscopy

Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a wide field-of-view (FOV) computational imaging method using lens-free on-chip microscopy to efficiently and cost-effectively scan biological samples such as pathology slides. Background: Wide field-of-view (FOV) and high-resolution imaging is crucial...

Published: 7/19/2023 | Inventor(s): Aydogan Ozcan, Alon Greenbaum, Yibo Zhang, Alborz Feizi, Wei Luo

Category(s): Life Science Research Tools, Electrical, Electrical > Imaging, Life Science Research Tools > Microscopy And Imaging, Software & Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Medical Devices > Medical Imaging

2019-737 Deep Learning-Based Color Holographic Microscopy

Summary: UCLA researchers in the Department of Electrical Engineering have developed a novel deep learning-based method that performs high-fidelity color image reconstruction using a single hologram. Background: Pathology slides are currently the gold standard in diagnostics for many diseases. Accurate color representations of well stained pathology...

Published: 7/19/2023 | Inventor(s): Aydogan Ozcan, Yair Rivenson, Tairan Liu, Yibo Zhang, Zhensong Wei

Keywords(s): Artifical Intelligence (Machine Learning, Data Mining), Artificial Neural Network, Computer Aided Learning, Confocal Microscopy, Cytopathology, Digital Holography, Electron Microscope, Fluorescence Microscope, Fluorescence-Lifetime Imaging Microscopy Leading Lights, Histology, Histopathology, Holography, Image Resolution, Imaging, Immunohistochemistry, Machine Learning, Magnetic Resonance Imaging Pathology, Medical Imaging, Microscope, Microscopy, Microscopy And Imaging, Neuropathology, Pathogen, Pathogenesis, Pathophysiology, Perceptual Learning, Unsupervised Learning , Wavelength

Category(s): Electrical, Electrical > Imaging, Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Software & Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Diagnostic Markers, Medical Devices > Medical Imaging

2019-002 Motility-Based Label-Free Detection of Parasites in Bodily Fluids Using Holographic Speckle Analysis and Deep Learning

Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed deep learning-based, cost-effective, and portable optical devices that facilitate label-free, high-throughput and sensitive detection of motile parasites. Background: Parasitic infections are a major global public health issue, but current screening...

Published: 10/25/2023 | Inventor(s): Aydogan Ozcan, Yibo Zhang, Hatice Ceylan Koydemir

Keywords(s): Algorithm, Artificial Intelligence, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Disease, Holography, Imaging, Infection, Infectious Diseases, Infectivity, Monitoring (Medicine), Optics, Software & Algorithms

Category(s): Software & Algorithms, Software & Algorithms > Image Processing, Life Science Research Tools, Diagnostic Markers, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Monitoring And Recording Systems, Platforms > Diagnostic Platform Technologies, Therapeutics > Infectious Diseases

Method for 3D Nonlinear Structured Illumination Super-resolution Imaging

Researchers at the University of Arizona have developed a super-resolution microscopy method that is faster, easier to use, and has less artifacts than current super-resolution methods. The result is a 3D dual-color stimulated emission depletion (STED) nonlinear structured illumination (NL-SIM) microscope. Using a combination of low coherent light and...

Published: 4/3/2023 | Inventor(s): Leilei Peng, Yu Li, Han Zhang

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry

Programmable In-Memory Computing Accelerator for Low-Precision Deep Neural Network Inference

Background In the era of artificial intelligence, various deep neural networks (DNNs), such as multi-layer perceptron, convolutional neural networks, and recurrent neural networks, have emerged and achieved human-level performance in many recognition tasks. These DNNs usually require billions of multiply-and-accumulate (MAC) operations, soliciting...

Published: 2/23/2023 | Inventor(s): Jae-Sun Seo, Shihui Yin, Mingoo Seok, Bo Zhang

Keywords(s): Artificial Intelligence, Circuits, Computational Machine, Electronics, Machine Learning

Category(s): Physical Science, Computing & Information Technology, Intelligence & Security

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