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Integrated Planning for Safer, Smarter Autonomous Urban Driving
This technology enables autonomous vehicles to plan high-level tasks and low-level motions in a unified, adaptive framework. By continuously sharing safety and efficiency information between planning layers, vehicles can make smarter decisions in complex, unpredictable urban environments. The result is safer navigation without sacrificing operational...
Published: 4/28/2026   |   Updated: 4/28/2026   |   Inventor(s): Shiqi Zhang, Yan Ding
Keywords(s): CleanTech
Category(s): Campus > Binghamton University, Technology Classifications > Engineering
Electromotive anti fibrotic substance administration for fibrotic diseases
This technology uses a gentle electrical current to deliver antifibrotic drugs like collagenase directly into fibrotic tissues, such as the bladder wall, enabling noninvasive, targeted treatment of fibrosis and improving tissue function without surgery. Background: Fibrosis of the bladder wall, particularly in the context of neurogenic bladder, represents...
Published: 4/28/2026   |   Updated: 4/28/2026   |   Inventor(s): Jeffrey Villanueva
Keywords(s): fibrosis, fibrous materials, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering
Northwestern Startup: HIDDEN-AI
Founded: 2021 Northwestern Inventor: Wing Kam Liu McCormick School of Engineering Mechanical Engineering & Civil and Environmental Engineering HIDENN-AI is developing convolution hierarchical deep-learning neural networks to simultaneously train, solve, and calibrate any advanced materials and manufacturing system, reducing solution...
Published: 4/27/2026   |   Updated: 4/27/2026   |   Inventor(s):  
Keywords(s): Startup with Northwestern IP
Category(s): Physical Sciences > Software & Services
Precision Gene Therapy for Diseases Driven by Endothelial Dysfunction
SHORT DESCRIPTION Dual promoter system constructs for tissue-specific and cell-type-specific gene expression, enabling precision gene therapy targeting endothelial dysfunction in specific organs. INVENTORS Youyang Zhao* Ann & Robert H Lurie Children's Hospital of Chicago * Principal Investigator NU...
Published: 4/27/2026   |   Updated: 4/27/2026   |   Inventor(s):  
Keywords(s): Cardiology and Cardiovascular disease, CMD - Cardiometabolic disease, CPD - Cardiopulmonary disease, Gene therapy, Pulmonary disease, Regenerative medicine, Targeted therapy, Therapeutics, Vascular disease
Category(s): Life Sciences > Therapeutics
MPL Protein Targeting for Cancer Therapy and Transplant Preparation
Application Non-genotoxic hematopoietic stem cell transplantation conditioning regimen. Key Benefits Selective depletion of hematopoietic stem cells creates adequate niche space to allow donor engraftment without significant off target effect. Non-genotoxic conditioning regimen. CAR-T cells can have an anti-MPL positive leukemia effect before...
Published: 4/27/2026   |   Updated: 4/27/2026   |   Inventor(s): Shanmuganathan (Shan) Chandrakasan, H. (Harold) Trent Spencer, Christopher Doering, Lauren Fleischer, Gianna Branella, Jaquelyn Zoine, Harrison Brown
Keywords(s): Antibodies, Cell Therapy, Oncology Treatments
Category(s): TechPub Algolia > Therapeutics
STING Agonist 8803 for Blood-Brain Barrier Opening in Glioblastoma Treatment
SHORT DESCRIPTION Chemical compound that opens the blood-brain barrier to enhance delivery of therapeutics for treating glioblastoma. INVENTORS Amy Heimberger* Northwestern University Feinberg School of Medicine, Department of Neurological Surgery * Principal Investigator NU 2025-212 IP STATUS US...
Published: 4/27/2026   |   Updated: 4/27/2026   |   Inventor(s):  
Keywords(s): AD - Alzheimer’s Disease, Adjunct therapy, ALS - Amyotrophic Lateral Sclerosis, Animal Model, Autoimmune disease, Cancer/Oncology, CNS - Central Nervous System, Drug delivery, Immunology, Immunotherapy, MS - Multiple Sclerosis, Neurodegenerative disease, Neurologic disease, PD - Parkinson's Disease, Repurposed Drugs, Research tool, Small molecule, Targeted therapy, TBI - Traumatic brain injury
Category(s): Life Sciences > Therapeutics, Life Sciences > Biomarkers & Biomedical Research Tools
Selective PAD2 Inhibitors for Neuroprotection in Traumatic Brain Injury
SHORT DESCRIPTION Novel PAD2-selective inhibitor platform targeting neuroinflammation to support both acute neuroprotection and long-term functional recovery as a first-in-class treatment of traumatic brain injury. INVENTORS Hasan Alam* Northwestern University Feinberg School of Medicine, Department of Surgery (Trauma...
Published: 4/27/2026   |   Updated: 4/27/2026   |   Inventor(s):  
Keywords(s): CNS - Central Nervous System, CVA - Cerebrovascular Accident, Neurodegenerative disease, Neuroinflammation, Neurologic disease, Neurology, Small molecule, Targeted therapy, TBI - Traumatic brain injury, Therapeutics
Category(s): Life Sciences > Therapeutics
Biomolecular Condensates as Protein Degradation Tools for Intracellular Targets
SHORT DESCRIPTION A targeted-protein degradation platform for intracellular targets, addressing resistant oncogenic and neurodegenerative targets. INVENTORS Shana Kelley* Weinberg College of Arts & Sciences, Department of Chemistry Yi Li * Principal Investigator NU 2025-050 IP STATUS PCT...
Published: 4/27/2026   |   Updated: 4/27/2026   |   Inventor(s):  
Keywords(s): AD - Alzheimer’s Disease, Biologic, Biomolecular condensates, Cancer/Oncology, Drug delivery, Nanoparticle, Neurodegenerative disease, Neurologic disease, Neurology, PD - Parkinson's Disease, Platform technology, Targeted protein degradation, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Biomarkers & Biomedical Research Tools
Methods to Treat Neurodegenerative Disorders by Reducing Nuclear Aggregates and Modulating Adenosine‑to‑Inosine RNA Editing
SHORT DESCRIPTION Novel disease‑modifying approach that dissolves toxic nuclear RNA–protein aggregates and restores synaptic function in neurodegenerative diseases by inhibiting adenosine‑to‑inosine (A‑to‑I) RNA editing and modulating ADAR enzymes. INVENTORS Joseph Mazzulli* Northwestern University Feinberg School...
Published: 4/27/2026   |   Updated: 4/27/2026   |   Inventor(s):  
Keywords(s): Lewy bodies, Neurodegenerative disease, Neurology, PD - Parkinson's Disease, RNA - Ribonucleic Acid, Small molecule, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
Mitigating aberrant Cdk5 Activation in SMA – A Novel Therapeutic Strategy Targeting Mitochondrial Function
SHORT DESCRIPTION A targeted strategy that mitigates aberrant Cdk5 activity to restore mitochondrial function and reduce motor neuron degeneration in SMA models. INVENTORS Yongchao Ma* Northwestern University Feinberg School of Medicine, Department of Pediatrics * Principal Investigator NU Tech...
Published: 4/27/2026   |   Updated: 4/27/2026   |   Inventor(s):  
Keywords(s): Adjunct therapy, Neurodegenerative disease, Neurologic disease, Neurology, Rare diseases, SMA - Spinal muscular atrophy, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
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