Search Results - tomography

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Radioligand for imaging brain PDE4 subtype D receptors with positron emission tomography
The technology relates to the first radioligands that can be used to image and quantify the enzyme phosphodiesterase subtype D (PDE4D). The PDE4D proteins have a role in carrying out signal transduction pathways in several cell types and is thought to be the key target of various antidepressants. Current work with imaging the radioligands in monkey...
Published: 10/28/2024   |   Inventor(s): Sanjay Telu, Robert Innis, Robert Nugent, Mark Gurney, Xuesheng Mo, Victor Pike
Keywords(s): brain, D, Emission, IMAGING, PDE4, Positron, Radioligand, RECEPTORS, Subtype, tomography, VEXXXX, VNXXXX, WBXXXX, WIXXXX, XCXXXX, XFXXXX
Category(s): Application > Diagnostics, Application > Research Materials, Application > Non-Medical Devices, TherapeuticArea > Neurology, TherapeuticArea > Psychiatry/Mental Health, Application > Medical Devices, Application > Software / Apps
Imaging Inflammation using PET Radioligands that Target Translocator Protein 18?kDa with High Affinity Regardless of Genotype
This technology includes a group of radioligands that label inflammatory cells specifically, accurately, and across different genotypes and can be detected using Positron Emission Tomography (PET). The radioligands target the Translocator protein 18 kDa (TSPO) receptor which is present on the outer mitochondrial membrane and is involved in the production...
Published: 10/28/2024   |   Inventor(s): Chad Brouwer, Victor Pike
Keywords(s): 18kDa, Emission, Genotype, Human, Listed LPM Fenn as of 4/15/2015, Positron, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Quantifying/imaging, Radioligands, Regardless, tomography, TSPO, VEXXXX, VNXXXX, WBXXXX, WIXXXX, XCXXXX, XFXXXX
Category(s): Application > Research Materials, Application > Diagnostics, TherapeuticArea > Neurology, Application > Medical Devices, Application > Non-Medical Devices, Application > Software / Apps, TherapeuticArea > Psychiatry/Mental Health
Imaging Inflammation using PET Radioligands that Target Translocator Protein 18?kDa with High Affinity Regardless of Genotype
This technology includes a group of radioligands that label inflammatory cells specifically, accurately, and across different genotypes and can be detected using Positron Emission Tomography (PET). The radioligands target the Translocator protein 18 kDa (TSPO) receptor which is present on the outer mitochondrial membrane and is involved in the production...
Published: 10/28/2024   |   Inventor(s): Robert Innis, Federico Da Settimo, Giorgio Stefancich, Sabrina Taliani, Sabrina Castellano, Claudia Martini, Yi Zhang, Victor Pike
Keywords(s): 18kDa, Emission, Genotype, Human, Listed LPM Fenn as of 4/15/2015, NA1XXX, Positron, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Quantifying/imaging, Radioligands, Regardless, tomography, TSPO, VEXXXX, VNXXXX, WBXXXX, WIXXXX, XCXXXX, XFXXXX
Category(s): TherapeuticArea > Psychiatry/Mental Health, Application > Non-Medical Devices, TherapeuticArea > Neurology, Application > Software / Apps, Application > Diagnostics, Application > Medical Devices, Application > Research Materials
Quantitative Measurement of Syndesmophytes in Ankylosing Spondylitis Using Computed Tomography (CT)
Syndesmophyte (abnormal bone) growth in the spine is a hallmark of Ankylosing Spondylitis, a type of inflammatory arthritis. Syndesmophyte growth is currently monitored using semi-quantitative scoring of radiographs, but radiographs consider only a small part of the vertebra, and the method is subject to reader error. Because syndesmophytes grow slowly,...
Published: 10/28/2024   |   Inventor(s): Sovira Tan
Keywords(s): AA3AXX, AA3XXX, AAXXXX, AXXXXX, RADIOGRAPHY, Spondylitis, Syndesmophytes, tomography
Category(s): Collaboration Sought > Collaboration
A Novel Tomographic Imaging System Using a Conformable Mirror
Description of TechnologyMichigan State University’s technology is a conformable mirror for use in computer-aided tomography (CT) systems. The design eliminates the need for an enclosed space, which is stressful for children and people with claustrophobia. The mirror is the only moving component. Software is used to construct the entire tomography...
Published: 6/8/2021   |   Inventor(s): Satish Udpa
Keywords(s): CT Scan, Medical Imaging, Tomography
Category(s): Medical, Computer Hardware