Search Results - infectivity

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ADENO-ASSOCIATED VIRUS VIRIONS AND METHODS OF USE THEREOF
ADENO-ASSOCIATED VIRUS VIRIONS AND METHODS OF USE THEREOF Researchers at UC Berkeley And. UCSF have developed a recombinant adeno-associated virus (rAAV) virion, comprising a variant AAV capsid protein, which can exhibit greater infectivity of a macrophage and has potential therapeutic applications. Adeno-associated virus (AAV) belongs to the Parvoviridae...
Published: 4/20/2023   |   Inventor(s): David Schaffer, Danqing Zhu, Tomasz Nowakowski, Galina Popava (Schmunk)
Keywords(s): Capsid, Delivery Method, Heterologous Nucleic Acid, Infectivity, Virion
Category(s): Technology Classifications > Biology
Novel Targets to Prevent Borrelia burgdorferi Infection and Lyme Disease
B. burgdorferi-infected ticks can cause Lyme disease in mammalian hosts. This technology relates to the use of B. burgdorferi outer surface proteins (BBA64 and BBA66) as Lyme disease vaccine candidates. In vivo animal studies demonstrate these outer surface proteins inhibit tick-to-host B. burgdorferi transmission. Presently, there is no vaccine approved...
Published: 4/8/2024   |   Inventor(s): Robert Gilmore
Keywords(s): BBA66, BORRELIA, BURGDORFERI, CDC Docket Import, CDC Docket Import CDC Prosecuting, COMPONENT, DA3XXX, DAXXXX, DB3XXX, DBXXXX, DC4XXX, DXXXXX, Gene, Infectivity, MAMMALIAN, Necessary, PATHOGEN, TICK, TRANSMISSION, Vector, Via
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Therapeutics, Application > Vaccines, Application > Diagnostics
2019-002 Motility-Based Label-Free Detection of Parasites in Bodily Fluids Using Holographic Speckle Analysis and Deep Learning
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed deep learning-based, cost-effective, and portable optical devices that facilitate label-free, high-throughput and sensitive detection of motile parasites. Background: Parasitic infections are a major global public health issue, but current screening...
Published: 10/25/2023   |   Inventor(s): Aydogan Ozcan, Yibo Zhang, Hatice Ceylan Koydemir
Keywords(s): Algorithm, Artificial Intelligence, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Disease, Holography, Imaging, Infection, Infectious Diseases, Infectivity, Monitoring (Medicine), Optics, Software & Algorithms
Category(s): Software & Algorithms, Software & Algorithms > Image Processing, Life Science Research Tools, Diagnostic Markers, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Monitoring And Recording Systems, Platforms > Diagnostic Platform Technologies, Therapeutics > Infectious Diseases
2020-849-LOW-COST, FAST AND COMPACT EXHALED BREATH CONDENSATE TECHNOLOGY
SUMMARY: UCLA researchers have developed a low-cost method for non-invasive infectious disease testing that can monitor large public spaces for signs of viral outbreaks. BACKGROUND: The ability to test for infectious diseases through non-invasive approaches has become even more prevalent today due to the COVID-19 pandemic. To monitor large populations...
Published: 7/19/2023   |   Inventor(s): Pirouz Kavehpour
Keywords(s): Diagnostic Test, Infection, Infectious Diseases, Infectivity, Medical Device, Viral Load
Category(s): Life Science Research Tools > Other Reagents, Diagnostic Markers, Therapeutics > Infectious Diseases, Therapeutics > Infectious Diseases > COVID