Search Results - shengxi+chen

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Targeted Therapy for Triple-Negative Breast Cancer
Breast cancer is the second leading cause of death in women and is the most common cancer among women worldwide. There are four main breast cancer subtypes, luminal A, luminal B, HER2-positive and triple-negative. Triple-negative breast cancer (TNBC) is highly invasive and has higher rates of metastasis and a worse prognosis. Metastasis of cancer cells...
Published: 9/12/2023   |   Inventor(s): Shengxi Chen, Xiaojiang Cui, Yi Zhang, Sidney Hecht
Keywords(s):  
Category(s): Life Science (All LS Techs), Advanced Materials/Nanotechnology, Cancer, Cancer Therapeutics, Pharmaceuticals
Novel Multi-Omics Aging Clock
­A multi-omics clock analyzes multiple layers of omics data with machine learning to predict remaining lifespan of mammals, particularly for animal model studies. Large omics data sets may be used from combinations of genomics, proteomics, lipids, etc. available from blood or other simple sample collection. This tool can robustly capture changes...
Published: 3/12/2024   |   Inventor(s): George Sutphin, Samuel Freitas, Megha Padi, Chen Chen
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Screening assays, Technology Classifications > Research Tools > Simulators and Modeling Tools
Autonomous Drone for railroad track inspection
Reference #: 01564 The University of South Carolina is offering licensing opportunities for Autonomous Drone for railroad track inspection Background: The current practices suffer from three main drawbacks: 1) Human pilot cost is significant. The schedule of the drone-based track inspection is contingent on the pilot’s availability rather than...
Published: 3/15/2023   |   Inventor(s): Yu Qian, Yi Wang, Chen Chen
Keywords(s): autonomous drone, flight control, image processing, railroad track inspection, self-navigation
Category(s): Engineering and Physical Sciences
Engineered globular endolysin, a highly potent antibacterial enzyme for multidrug resistant Gram-negative bacteria
[Licensing negotiation in progress] [Invitation for Expression of Interest- Deadline 2 July 2021] We are inviting expressions of interest (EoI) for commercializing “Engineered Globular Endolysin, a Highly Potent Antibacterial Enzyme for Multidrug Resistant Gram-Negative Bacteria” technology. The innovation is developed by Professor XIA...
Published: 10/17/2023   |   Inventor(s): Jiang XIA, Shui Yee LEUNG, Xi CHEN, Miao LIU
Keywords(s):  
Category(s): Biotechnology, Therapeutics
2015-671 Underground Shafts for Hydrogen Storage
SummaryResearchers at UCLA have developed an underground drilled shaft concept for storage of hydrogen or other gases.BackgroundOne challenge in creating a hydrogen economy is developing hydrogen gas storage solutions. Increased interest has helped the global hydrogen storage market grow to $2.6 billion in 2016, and it is expected to reach over $5...
Published: 7/19/2023   |   Inventor(s): Adrienne Lavine, Hossein Kavehpour, Dante Simonetti, Richard Wirz, Chen Chen, Gabriela Bran, Gopinath Warrier, Hamarz Aryafar, Jonathon Kennedy, Joshua Jordan, Keith Lovegrove
Keywords(s): Energy & Water
Category(s): Energy & Environment > Energy Generation > Solar, Energy & Environment > Energy Storage
Compositions for Treatment of HER2 Positive Cancers
Many early stage cancers have a high rate of survival if promptly diagnosed and treated. Survival rates for stage 1-3 breast cancer can be as high as 95% at the 5 year mark. Unfortunately, late stage cancers have a much lower survival rate; stage 4 breast cancer only has about a 20% survival rate at the 5 year mark. Metastatic cancers pose a particularly...
Published: 2/23/2023   |   Inventor(s): Shengxi Chen, Yanmin Zhang, Sidney Hecht
Keywords(s): Cancer, Chemicals, DNA nanotechnology, Drug Delivery, Peptides
Category(s): Cancer Therapeutics, Life Science (All LS Techs), Pharmaceuticals, Advanced Materials/Nanotechnology
Compositions for Treatment of HER2 Positive Cancers
Many early stage cancers have a high rate of survival if promptly diagnosed and treated. Survival rates for stage 1-3 breast cancer can be as high as 95% at the 5 year mark. Unfortunately, late stage cancers have a much lower survival rate; stage 4 breast cancer only has about a 20% survival rate at the 5 year mark. Metastatic cancers pose a particularly...
Published: 2/23/2023   |   Inventor(s): Shengxi Chen, Sidney Hecht
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Cancer Therapeutics, Life Science (All LS Techs), Pharmaceuticals
Tools for Rapid, Single-Molecule Sensitivity, Detection of Viral Nucleic Acids
Dengue is a mosquito-borne viral infection that is one of the leading causes of illness and death in the subtropical and tropical areas of the world. The incidence of dengue is growing rapidly, threatening more than 2.5 billion people in more than 100 countries. Symptoms of dengue virus infection can be severe with fatality rates as high as 10% in the...
Published: 2/23/2023   |   Inventor(s): Shengxi Chen, Mingxuan Gao, Sidney Hecht
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Diagnostic Assays/Devices, Life Science (All LS Techs), Genomic Assays/Reagents/Tools
RNA Detection Tool without Amplification
RNA plays a central role in almost all living organisms and as such detecting its presence or overexpression can be useful in a wide range of clinical diagnostics and other analyses. Traditional methods for detecting RNA include amplification schemes to increase the detection signal. Recent efforts have utilized real-time RT-PCR methods to detect RNA,...
Published: 2/23/2023   |   Inventor(s): Shengxi Chen
Keywords(s):  
Category(s): Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices, Genomic Assays/Reagents/Tools, Diagnostic Assays/Devices
Synthesis of Glycoproteins using Modified Bacterial Ribosomes
Glycoproteins play an important role in numerous cellular and biological processes such as intercellular communication and trafficking, immune functions, cell-cell recognition, hormones, reproduction, embryonic development and more. They are also closely associated with a number of diseases like cancer and immunodeficiency diseases. In nature, the formation...
Published: 2/23/2023   |   Inventor(s): Sidney Hecht, Larisa "liza" Dedkova, Shengxi Chen, Xiaoguang Bai
Keywords(s):  
Category(s): Biomaterials, Life Science (All LS Techs), Pharmaceuticals, Proteomic Assays/Reagents/Tools, Applied Technologies, Bioanalytical Assays, Chemistries & Devices
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