Search Results - magnetic+resonance+imaging

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Time Efficient Multi-Pulsed Field Gradient (mPFG) MRI Without Concomitant Gradient Field Artifacts
Abstract: Measuring and mapping nervous tissue microstructure noninvasively is a long sought-after goal in neuroscience. Clinically, several neuropathologies such as cancer and stroke, are associated with changes in tissue microstructure. Diffusion tensor imaging (DTI), which models diffusion anisotropy, is an ideal imaging modality to elucidate these...
Published: 4/8/2024   |   Inventor(s): Peter Basser, Michal Komlosh, Magdoom Mohamed Kulam Najmudeen
Keywords(s): Basser, Diffusion Tensor Distribution MR Imaging, DTI, Eunice Kennedy Shriver National Institute of Child Health an, Komlosh, Magnetic Resonance Imaging, mPFG, MRI, Multi-Pulsed Field Gradient, Najmudeen, NICHD
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Application > Diagnostics, TherapeuticArea > Immunology
Denoising of Dynamic Magnetic Resonance Spectroscopic Imaging Using Low Rank Approximations in the Kinetic Domain
Abstract: Accurate measurement of low metabolite concentrations produced by medically important enzymes is commonly obscured by noise during magnetic resonance imaging (MRI). Measuring the turnover rate of low-level metabolites can directly quantify the activity of enzymes of interest, including possible drug targets in cancer and other diseases. Noise...
Published: 4/8/2024   |   Inventor(s): Jeffery Brender, Kazutoshi Yamamoto, Jeeva Munasinghe, Shun Kishimoto, Hellmut Merkle, Murali Cherukuri, James Mitchell
Keywords(s): 13C imaging, Brender, Denoising, DNP, Dynamic Nuclear Polarization, Glucose Metabolism, Low Metabolite Concentration, Magnetic Resonance Imaging, Metabolic Enzymes, MRI, Software Plugin, SPECTROSCOPIC
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Software / Apps, TherapeuticArea > Oncology
Tamperless Tensor Elastography Imaging
Abstract: Measuring and mapping nervous tissue microstructure noninvasively is a long sought-after goal in neuroscience. Several neuropathologies – such as cancer and stroke – are associated with changes in tissue microstructure. Changes in material properties, such as stiffness, represent a sensitive measure of underlying changes in tissue architecture,...
Published: 4/8/2024   |   Inventor(s): Peter Basser, Magdoom Mohamed Kulam Najmudeen
Keywords(s): Alzheimer’s Disease, Anisotropy, Basse, brain, CANCER, Elasticity Tensor, Elastography, Eunice Kennedy Shriver National Institute of Child Health an, Magnetic Resonance Imaging, MRI, Najmudeen, NICHD, TBI, TRAUMA, Traumatic Brain Injury
Category(s): TherapeuticArea > Neurology, Application > Diagnostics, TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing
MRI-Based Method for Characterizing Axonal Microstructure in Traumatic Brain Injury
Abstract: Neurites of the central nervous system can be conceptualized as cylindrical pores with finite lengths and radii. In response to physical trauma, axons may assume a “beaded” morphology which alters their ability to conduct electrical impulses, impairing brain function. These microstructural changes are thought to underlie some of the cognitive...
Published: 4/8/2024   |   Inventor(s): Peter Basser, Dan Benjamini, Michal Komlosh
Keywords(s): Magnetic Resonance Imaging, MRI, MRI diagnostic, Neurites, Peripheral Nervous System, PNS, TBI, Traumatic Brain Injury
Category(s): Application > Diagnostics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Neurology
Methods of Determining Homeostatic Perturbations
Abstract: Biological homeostasis is a state of steady internal, physical, and chemical conditions maintained by a living organism observed at the cellular level.  Biological homeostasis can vary in order to alter the cellular physical and chemical conditions. Thus, it acts as a mechanism to define the physiological state of cellular activity; for instance...
Published: 4/8/2024   |   Inventor(s): Rea Ravin, Nathan Williamson, Teddy Cai, Peter Basser
Keywords(s): Basser, Biomarkers, Central Nervous System, CNS, functional imaging, HOMEOSTASIS, Magnetic Resonance Imaging, MRI, NICHD, NMR, Nuclear Magnetic Resonance, r, Steady-state, The Eunice Kennedy Shriver National Institute of Child Healt
Category(s): TherapeuticArea > Oncology, TherapeuticArea > Neurology, Application > Diagnostics, Collaboration Sought > Licensing
Quantitative In Vivo Methods for Measuring Brain Networks
Abstract: The pattern or latency connectome was hypothesized to change in physiological development and disease.  For example, in amyotrophic lateral sclerosis (ALS), large diameter axons are damaged selectively – while in autism, small-diameter axons may be over-expressed. These anatomical changes are expected to alter the latency connectome or pattern...
Published: 4/8/2024   |   Inventor(s): Peter Basser
Keywords(s): Axon diameter distribution, connectome, DTI Tractography, Magnetic Resonance Imaging, MRI, MRI diagnostic
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, Application > Diagnostics
Multidimensional MRI Signature for Specific Detection of Traumatic Brain Injury In Vivo
Abstract: Traumatic brain injury (TBI) represents a major medical, social and economic concern worldwide due to significant mortality – especially among younger populations – and long-term disabilities. Various pathological brain lesions (e.g., intracerebral bleedings, necrotic-ischemic lesions, tissue avulsion) are produced by impacting mechanical...
Published: 4/8/2024   |   Inventor(s): Dan Benjamini, Peter Basser, Diego Iacono
Keywords(s): Amyloid Precursor Protein, Be, DAI, Diffuse Axonal Injury, Eunice Kennedy Shriver National Institute of Child Health an, Magnetic Resonance Imaging, MRI, MULTIDIMENSIONAL, NICHD, TAI, TBI, Traumatic Axonal Injury, Traumatic Brain Injury
Category(s): TherapeuticArea > Neurology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics
A Uniform AI Framework for Automated Detection of Disease-Related Risk Factors in 3D Medical Imaging Data
Summary: UCLA researchers from the Departments of Anesthesiology & Perioperative Medicine, Ophthalmology, Computational Medicine, and Computer Science have developed a novel uniform framework to diagnose disease-related risk factors in any volumetric medical imaging data. Background: Automated diagnosis of medical imaging is undoubtedly important...
Published: 10/4/2024   |   Inventor(s): Oren Avram, Eran Halperin, Berkin Durmus, Nadav Rakocz, Jeffrey Chiang, Srinivas Sadda
Keywords(s): Advanced Computing / AI, AI algorithms, Artifical Intelligence (Machine Learning, Data Mining), Artificial Intelligence, Biomarker, Biomedical Engineering, Computer-Aided Design, Deep Learning, Imaging, Magnetic Resonance Imaging, Medical Imaging
Category(s): Software & Algorithms, Software & Algorithms > Digital Health, Software & Algorithms > Image Processing, Software & Algorithms > Artificial Intelligence & Machine Learning, Medical Devices > Medical Imaging
New MRI acquisition and post-processing technique for improved breast cancer diagnosis
New computational imaging platform can improve patient-specific characterization of breast cancerProblemClinicians rely on imaging to direct the path of treatment for breast cancer. The current standards for vascular imaging, MRI and CT, can miss valuable information. Fortunately, there has been a wave of technical progress with digital health technologies....
Published: 11/5/2024   |   Inventor(s): Thomas Yankeelov, Chengyue Wu, David Hormuth, Todd Oliver, Robert Moser, Greg Karczmar, Federico Pineda, Ty Easley, Rina Barber, Boyl Kim, Deepa Sheth, Aytek Oto, Hiroyuki Abe, Milica Medved, Xiaobing Fan, Aritrick Chatterjee, Shiyang Wang
Keywords(s): Cancer, Diagnostics, Imaging, Magnetic resonance imaging, Medical imaging, MRI
Category(s): Life sciences > Medical technology > TechBio (software innovation in healthcare), Life sciences > Diagnostic, Software > Digital health
2022-088 Neural Networks for Adipose Tissue Segmentation on Magnetic Resonance Images
Summary: UCLA researchers in the Department of Radiological Sciences have developed a novel neural network that can segment and quantify visceral and subcutaneous adipose tissues on magnetic resonance images automatically, accurately, and rapidly, to enhance clinical methods for characterizing and monitoring risk for cardiometabolic diseases in patients...
Published: 9/25/2024   |   Inventor(s): Holden Wu, Sevgi Gokce Kafali-Tekat
Keywords(s): Advanced Computing / AI, Artificial Neural Network, Artificial Neural Network Artificial Neuron, cardiometabolic disease, Hypertension, Imaging, Machine Learning, Magnetic Resonance Imaging, Magnetic Resonance Imaging Pathology, Medical Imaging, MRI, multi-contrast imaging, obesity, Tissue (Biology), tissue annotation, tissue detection, tissue ribbons alignment, tissue segmentation
Category(s): Medical Devices > Medical Imaging, Platforms > Diagnostic Platform Technologies, Medical Devices > Medical Imaging > MRI, Therapeutics > Metabolism And Endocrinology
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