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RNA Binding Motif 3 (RBM3) Overexpressing Transgenic Mouse
Advantages • RBM3 upregulation reverses multiple tau phosphorylations post-TBI • Novel RBM3 Overexpressing Transgenic Mouse Model allows researchers to study the effects of RBM3 activation on tissue function, brain function, and brain injury Summary Traumatic brain injury (TBI) not only causes immediate neuronal damage but also...
Published: 5/30/2025
|
Inventor(s):
Travis Jackson
Keywords(s):
Animal Models
,
Neuroscience
Category(s):
Technology Classifications > Research Tools/Copyright > Animal Models
,
Technology Classifications > Medical > Neuroscience
,
Technology Classifications > Medical > Biotechnology
Method for Co-Localizing Two Proteins on the Inside of the Cell Membrane in Yeast
Advantages Localization of protein interactions at the cell membrane offers a more physiologically relevant model Improved screening by minimizing off-target interactions Broadly applicable and accessible tools Summary Protein-protein interactions involving membrane proteins are notoriously difficult to study under physiologically relevant conditions....
Published: 5/30/2025
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Inventor(s):
Lawrence Stern
,
Michael Nelson
Keywords(s):
Drug Discovery
Category(s):
Technology Classifications > Medical > Cell & Tissue Engineering
,
Technology Classifications > Medical > Medical Diagnostics
,
Technology Classifications > Medical > Biomaterials
Transgenic Foxc
2
-tdTomato Overexpressing Mouse Model for Study and Screening of Lymphatic Valve Development
Advantages Tissue specific Foxc
2
expression with integrated tdTomato fluorescent reporter enables precise spatiotemporal visualization Enables monitoring of lymphatic valve development 1:1 co-expression of Foxc2 and tdTomato, overcoming expression variability characteristic associated with of IRES-based or viral delivery systems Single-vector...
Published: 5/30/2025
|
Inventor(s):
Joshua Scallan
Keywords(s):
Animal Models
Category(s):
Technology Classifications > Research Tools/Copyright > Animal Models
Synthesis of Non-steroidal Anti-Inflammatory Compounds to Promote Wound Healing
Graph shows the average skin punch biopsy weight of mice treated topically with nitrogen mustard (NM) to induce skin inflammation. Mice additionally treated with polyamine-imidazole conjugates showed a marked decrease in skin inflammation. Invention Summary: Non-steroidal Anti-Inflammatory drugs (NSAIDs) are widely available for over-the-counter...
Published: 5/30/2025
|
Inventor(s):
Jeffrey Laskin
,
Ned Heindel
,
Christophe Guillon
Keywords(s):
Category(s):
Technology Classifications > Therapeutics
,
Technology Classifications > Healthcare & Life Sciences
Repurposed Receptor Blocker for the Treatment of PTSD
Application Use of neurokinin 3 receptor antagonist, osanetant, for the prevention and treatment of post-traumatic stress disorder (PTSD) and other anxiety disorders. Key Benefits Utilizes a repurposed drug that is safe for human use. Potential to treat specific PTSD symptoms better than antidepressants. Market Summary Post-traumatic stress...
Published: 5/30/2025
|
Inventor(s):
Kerry Ressler
,
Raul Andero Gali
Keywords(s):
Neurology and Pain Treatments
,
Repurposed Drug
Category(s):
TechPub Algolia > Therapeutics
Computerized Cognitive Training for Insomnia (COGMUSE)
Advantages Gamified cognitive training that is aimed at adults with both autism and insomnia Flexibility in terms of the ability to incorporate user feedback Summary Older adults with insomnia as well as autistic adults with co-occurring insomnia often struggle with persistent cognitive and sleep disturbances. These issues are only marginally...
Published: 5/30/2025
|
Inventor(s):
Ashley Curtis
Keywords(s):
Biotechnology
,
Computer Science
,
Computers Software and Information Technology
,
Health Tech
,
Human Computer Interfaces
,
Neuroscience
,
Psychiatry / Mental Health
,
Therapeutics
Category(s):
Technology Classifications > Computer Science > Computers Software & Information Technology
,
Technology Classifications > Medical > Neuroscience
,
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Engineering > Computer Engineering
Real-Time Program-Specific Log Consolidation for Intrusion Detection
Advantages Reduces logs
2
19× for efficient data storage Performs real-time analysis with zero offline cost Minimizes memory use through subject activity consolidation Maintains high detection accuracy with low alert fatigue Summary Enterprises today are increasingly targeted by Advanced Persistent Threats (APTs), stealthy, long-term attacks...
Published: 5/30/2025
|
Inventor(s):
Yao Liu
,
Xiao Han
,
Zhuo Lu
Keywords(s):
Computer Science
,
Cybersecurity
Category(s):
Technology Classifications > Computer Science > C/S Cybersecurity
,
Technology Classifications > Computer Science > Algorithms
,
Technology Classifications > Computer Science > Computers Software & Information Technology
,
Technology Classifications > Computer Science > Datasets
Layer-Wise Filter Thresholding
Advantages Layer-Specific Dynamic Thresholding High Compression with Accuracy Preservation No Retraining Required Profiling-Driven Pruning Strategy Edge-Device Friendly Architecture Summary Deploying AI on IoT edge devices is limited by the high computational and memory demands of traditional convolutional neural networks (CNNs). These constraints...
Published: 5/30/2025
|
Inventor(s):
Srinivas Katkoori
,
Lakshmi Kavya Kalyanam
Keywords(s):
Artificial Intelligence
,
Internet of Things / IoT
Category(s):
Technology Classifications > Computer Science > Computers Software & Information Technology
,
Technology Classifications > Computer Science > Algorithms
,
Technology Classifications > Computer Science > Datasets
Empowering Resource-Constrained IoT Edge Devices: A Hybrid Approach for Edge Data Analysis
Advantages Optimized for low-power, memory-constrained IoT hardware Boosts model accuracy with minimal computational cost Reduces energy usage through efficient inference methods Enables real-time, on-device decision-making Easily scalable for diverse IoT applications Summary As the Internet of Things (IoT) continues to scale across industries—from...
Published: 5/30/2025
|
Inventor(s):
Srinivas Katkoori
Keywords(s):
Datasets
,
Internet of Things / IoT
Category(s):
Technology Classifications > Computer Science > Algorithms
,
Technology Classifications > Computer Science > Computers Software & Information Technology
,
Technology Classifications > Data/AI > D/AI Imaging
Stepped OFDM with Random Pattern
Advantages Increases maximum unambiguous velocity Enhances velocity and range resolution Enables joint radar and communication in a single waveform Reduces hardware complexity (single ADC) Maintains radar performance with randomized patterns Summary The rapid growth of mobile networks and radar systems has created an urgent need for high-performance...
Published: 5/30/2025
|
Inventor(s):
Joshua Ranstrom
,
Gokhan Mumcu
,
Mingzhe Bian
,
Huseyin Arslan
Keywords(s):
Radar/ Lidar Systems
,
Telecommunication / Wireless Communication
Category(s):
Technology Classifications > Computer Science > C/S Sensors
,
Technology Classifications > Electronics > Electronics Telecommunications
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