Search Results - david+cormode

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A Method for One-Step, Aqueous Phase Generation of Ultrasmall Inorganic Nanoparticles for Biomedical Applications.
A method to generate homogenous and stable inorganic nanoparticles (NPs) using a microfluidic device with two jet inlets. Problem: Inorganic nanoparticles have promise as contrast agents and therapeutics due to their high renal clearance and therefore low toxicity. However, they are limited by factors including complex synthesis routes with unfavorable...
Published: 1/21/2026   |   Inventor(s): David Cormode, Hyun (Michel) Koo, Nil Kanatha Pandey, Andrea Kian, Portia Maidment, Derick Rosario Berrios
Keywords(s): Microfluidics, Platform Technology, Radiology
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Research Tools & Reagents
An iron oxide nanozyme formulation for augmenting the efficacy of oral care products.
A combinatory formulation for oral care products that enhances antimicrobial specificity, anti-plaque potency and prevents tooth decay. Problem: Tooth decay (dental caries), caused by the destruction of the outer layer (enamel) of teeth by bacteria in biofilms, affects nearly half of the global population and remains the most prevalent chronic disease...
Published: 8/19/2025   |   Inventor(s): Yue Huang, Hyun (Michel) Koo, David Cormode
Keywords(s): Bioengineering, Dentistry, Infectious Disease, Microbiome, Nanotechnology, Platform Technology
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Materials, Technology Classifications > Therapeutics
Revolutionizing CT Imaging: Gold Nanoparticles with Biodegradable Polymer Encapsulation
Innovative CT contrast agent using biodegradable polymer-encapsulated gold nanoparticles for enhanced imaging and safe excretion. Problem: Gold particles emerged as promising contrasting agents due to their high X-ray attenuation, but their size-dependent behavior posed a challenge. Particles larger than 5nm raised toxicity concerns due to potential...
Published: 2/12/2024   |   Inventor(s): David Cormode
Keywords(s):  
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Imaging, Technology Classifications > Research Tools & Reagents
X-Ray Irradiation-Activated Hydrogel for Effective On-Demand Treatment of Glioblastoma and Other Tumors
Primary tumor reoccurrence often occurs following surgical resection in glioblastoma multiforme patients. Current hydrogel approaches deliver therapeutics using light or pH, but these approaches are limited by the tumor microenvironment. Researchers have developed an injectable hydrogel with unique materials that can be activated by X-ray irradiation...
Published: 1/12/2024   |   Inventor(s): Mathilde Bouche, David Cormode, Saad Sheikh, Jay Dorsey
Keywords(s): Drug Delivery, Hydrogels, Oncology
Category(s): Technology Classifications > Therapeutics, Technology Classifications > Materials