Search Results - dentistry

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Adhesive Microparticle Formulation For Localized And Sustained Drug Delivery
A hairy, water-in-oil-in-water microemulsion for prolonged delivery of one or more active ingredients while adhering to target tissues. Problem: Microparticles are promising drug delivery platforms due to their biocompatibility and stability. However, existing particle-based drug delivery systems are unable to fulfill the needs for prolonged delivery...
Published: 11/13/2024   |   Inventor(s): Daeyeon Lee, Minjun Oh, Jaehyun Kim, Li-Wei Chang, Robert Mauck, George Dodge, Hyun (Michel) Koo
Keywords(s): Bioengineering, Dentistry, Drug Delivery, Drug Target
Category(s): Technology Classifications > Materials
An iron oxide nanozyme formulation for augmenting the efficacy of oral care products.
A combinatory formulation for oral care products that enhances antimicrobial specificity, anti-plaque potency and prevents tooth decay. Problem: Tooth decay (dental caries), caused by the destruction of the outer layer (enamel) of teeth by bacteria in biofilms, affects nearly half of the global population and remains the most prevalent chronic disease...
Published: 10/8/2024   |   Inventor(s): Yue Huang, Hyun (Michel) Koo, David Cormode
Keywords(s): Bioengineering, Dentistry, Infectious Disease, Microbiome, Nanotechnology, Platform Technology
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Materials, Technology Classifications > Therapeutics
Microrobotics for Precision Biofilm Diagnostics and Treatment
Magnetic, scalable, tether-free robotic device for sampling infectious and contaminating biological materials from confined or difficult-to-access surfaces and spaces, for use in diagnoses, composition analysis, and treatments. Problem: Biofilms are microbial communities embedded within an extracellular matrix, forming a highly organized structure...
Published: 7/9/2024   |   Inventor(s): Hyun (Michel) Koo, Edward Steager
Keywords(s): Bioengineering, Dentistry, Infectious Disease, Nanotechnology, Platform Technology
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Robotics
Mannan-Degrading Enzymes (MDEs) Disrupting Bacterial-Fungal Biofilms for Prevention of Dental Cavities
Enzymes that degrade mannose to prevent the formation of bacterial-fungal biofilms, which cause dental cavities Problem: Dental cavities are among the most common oral diseases among children and adults in the United States, with treatments for this condition exceeding $81 billion annually. Dental cavities occur when the bacteria Streptococcus mutans...
Published: 7/9/2024   |   Inventor(s): Geelsu Hwang, Atul Dhall, Hye-Eun Kim
Keywords(s): Dentistry, Infectious Disease
Category(s): Technology Classifications > Therapeutics
Gum-Health Promoting Smart Dental Implant System
Dental implant that inhibits plaque accumulation and gingival tissue inflammation by photobiomodulation therapy delivered by embedded light-emitting diodes (LEDs) powered by electricity generated from the patient’s own oral motion. Problem: More than half of adults will lose one or more teeth in their lifetime. When a patient loses a tooth the...
Published: 7/9/2024   |   Inventor(s): Geelsu Hwang, Hye-Eun Kim, Albert Kim
Keywords(s): Bioengineering, Cell Therapy, Dentistry, Immunology, Immunoncology, Infectious Disease, Inflammation
Category(s): Technology Classifications > Medical Devices
The two step neutralizing mouth wash to minimize the effects of acid erosion on tooth enamel.
The Problem Dental erosion is a significant oral health problem. It is exacerbated by highly acidic diets, certain medications causing low salivary flow, and systemic conditions such as gastroesophogeal reflux (GERD), and bulimia. Erosive tooth wear from hydrochloric acid occurs when stomach juice is regurgitated in conditions such as GERD and bulimia....
Published: 1/10/2023   |   Inventor(s): Mojdeh Dehghan, Daranee Versluis
Keywords(s): Dental product, Dentistry
Category(s): Human Health
Neutramel Lollipops & Lozenges: Easy, Practical, and Immediate Saliva Neutralization and Remineralization for treatment of Tooth Erosion
The ProblemDental erosion is a significant oral health problem. Exacerbation can be externally caused, such as highly acidic diets and medications reducing salivary flow. Systemic conditions such as gastroesophogeal reflux (GERD), and bulimia also contribute to erosive tooth wear as regurgitation of stomach acid exposes the enamel to the abrasive nature...
Published: 8/31/2023   |   Inventor(s): Mojdeh Dehghan, Hassan Almoazen, Daranee Versluis
Keywords(s): Dental product, Dentistry, Drug Delivery
Category(s): Human Health