Search Results - platform

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Smartphone Diagnostic for Rapid Respiratory Virus Detection
Application Diagnostic and automatic surveillance platform to identify RSV, Influenza A, and COVID-19 in real-time. Key Benefits Rapid smartphone-based detection of multiple respiratory viruses in nasal swab, breath condensate, and saliva. Requires few reagents and no expensive equipment. Limit of detection on par with PCR and rapid readout. Enables...
Published: 8/22/2024   |   Inventor(s): Selma Piranej, Khalid Salaita
Keywords(s): COVID19, Microbiology/Infectious Diseases, Platform, Respiratory
Category(s): TechPub Algolia > Diagnostics
Drug Platform for L-Asparaginases for the Treatment of Leukemias
Application A novel humanized therapeutic L-asparaginase compound to treat acute lymphoblastic leukemia (ALL) and other cancers. Key Benefits A novel drug discovery platform for developing asparaginase-based compounds to treat leukemias and other cancers. The derivatives could exhibit less immunogenicity and systemic toxicity than FDA-approved...
Published: 8/22/2024   |   Inventor(s): Sunil Raikar, Christopher Doering, H. (Harold) Trent Spencer, Kristopher Knight, Harrison Brown
Keywords(s): Oncology, Pediatrics, Platform
Category(s): TechPub Algolia > Drug Discovery
Automated Sleep Analysis Using Cardiovascular Signals
Application Sleep stage classification algorithm and diagnostic platform. Key Benefits Real-time sleep classification using a single electrocardiogram sensor. Eliminates the need for multiple head, eye, skin, and heart sensors with current diagnostics. Preliminary results using human data demonstrate high accuracy in identifying different sleep...
Published: 7/30/2024   |   Inventor(s): Gari Clifford, Shamim Nemati, Qiao Li, Supreeth Shashikumar
Keywords(s): Artificial Intelligence, Cardiovascular, Platform
Category(s): TechPub Algolia > Software
Machine Learning Diagnostic for Automated Identification and Classification of Bone Marrow Cells
Application Machine learning tool to aid in the diagnosis of hematologic disorders of bone marrow. Key Benefits Automated machine learning-based approach for performing bone marrow differential counts that accounts for all viable cells on the smear. Data generated by a prototype shows the system is fast and demonstrates precision compared to manual...
Published: 7/30/2024   |   Inventor(s): Lee Cooper, David Gutman, David Jaye, Ahmed Aljudi, Ramraj Chandradevan
Keywords(s): Platform
Category(s): TechPub Algolia > Research Tools, TechPub Algolia > Software, TechPub Algolia > Diagnostics
Improving CAR T cell efficacy with Cytokine-Loaded Microparticles
Application Novel reagents for manufacturing of CAR T cells with improved characteristics. Key Benefits A multi-cytokine backpack particle that can be used during manufacturing process of CAR T treatments to improve their phenotype and efficacy. Preliminary data show the method can transduce primary healthy and patient T cells and promote CAR...
Published: 8/22/2024   |   Inventor(s): Sarwish Rafiq, Erik Dreaden, A K M Nawshad Hossian, Biaggio Uricoli
Keywords(s): Oncology, Platform
Category(s): TechPub Algolia > Micro and Nanotechnology
Liquid-hydrogel Hybrid Microfluidic Device
Application Measurement device for detecting of single-cell dynamics under environment perturbations or drug treatment. Key Benefits Fast determination of drug sensitivity. Long-term continuous cell-fate tracking. Time-lapse analysis of cell proliferation. Cell community analysis: intra-species interactions, inter-species interactions. Market...
Published: 7/30/2024   |   Inventor(s): Kyle Allison, Xin Fang, Devina Puri
Keywords(s): Imaging, Microbiology/Infectious Diseases, Platform
Category(s): TechPub Algolia > Diagnostics, TechPub Algolia > Research Tools, TechPub Algolia > Medical Device
Intranasal Nebulizer with Disposable Drug Cartridge for Improved Delivery of Vaccines and Therapeutics
Intranasal delivery is a simple, inexpensive and needle-free route for administration of vaccines and therapeutics. This intranasal delivery technology, developed with Creare LLC., includes low-cost, disposable drug cartridges (DDCs) that mate with a durable hand-held device. The rechargeable-battery-powered device transmits ultrasonic energy to the...
Published: 7/25/2024   |   Inventor(s): James Barry, Nabil Elkouh, Mark Bagley, Darin Knaus, Robert Trabka, Eric Friets, James Norris, Mark Papania
Keywords(s): AB1XXX, AB3FXX, AB3GXX, AB3XXX, AB4XXX, Able, ABXXXX, AC1XXX, ACXXXX, AEROSOL, AEROSOL-GENERATING, AEROSOLIZATION, Aerosolized, AEROSOLS, AXXXXX, BACTERIA, Bacterial, BACTERIAL VACCINES, CARTRIDGE, CDC, CDC Docket Import, CDC Docket Import CDC Prosecuting, Chamber, COOLING, DB1XXX, DB2XXX, DB3XXX, DB4XXX, DB5XXX, DBXXXX, DC1XXX, DC2XXX, DC3XXX, DC4XXX, DC5BXX, DC5XXX, DC6XXX, DCXXXX, Delivery, DEVICE, Devices, Disposable, DRUG, Drug Delivery, DXXXXX, FUNGAL, HAND, Having, INSERT, Intranasal, Methods, NASAL, NEBULIZER, NIOSH-PRL, OID-NCIRD-DVD, PLATFORM, Platforms, Pulmonary, respiratory, Respiratory Diseases, respiratory INFECTION, System, SYSTEMS, therapeutic, therapeutic delivery, Vaccine, VACCINE DELIVERY, Vaccine Design, VACCINE DEVELOPMENT, VBXXXX, viral, viral vaccine, VJXXXX, VKXXXX, VLXXXX, VOXXXX, VPXXXX, WAXXXX, WFXXXX, WJXXXX, WKXXXX, WMXXXX, XDXXXX, YBXXXX, YCXXXX, YFXXXX
Category(s): Collaboration Sought > Licensing, Application > Occupational Safety and Health, Application > Medical Devices, Application > Diagnostics, Application > Vaccines, Application > Therapeutics, TherapeuticArea > Dental, TherapeuticArea > Infectious Disease, TherapeuticArea > Endocrinology, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Ophthalmology, Application > Consumer Products, TherapeuticArea > Oncology
Diagnostics, Vaccines, and Delivery-Vehicles Related to Novel Phlebovirus
This CDC invention relates to primers and probes that specifically hybridize with Heartland virus (HRTLDV), a unique member of the genus Phlebovirus. It further relates to polyclonal antibodies specific for HRTLDV proteins. Serological detection assays using HRTLDV nucleic acid molecules, proteins, probes, primers, and antibodies are provided. Importantly,...
Published: 7/25/2024   |   Inventor(s): Stuart Nichol, William Nicholson, Cynthia Goldsmith, Aubree Kelly, Laura McMullan
Keywords(s): AC4XXX, ACXXXX, ANTIBODY, ANTIGEN, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, Compositions, DA4BXX, DA4XXX, DAXXXX, DC1XXX, DC5BXX, DC5XXX, DCXXXX, DDXXXX, Delivery, delivery system, DEVELOPED, diagnostic, DXXXXX, GB2CXX, GB2XXX, GBXXXX, GCXXXX, GENE THERAPY, gene transfer, GXXXXX, heartland, heartland virus, Hospitalized, Identification, ISOLATES, Isolation, Methods, Missouri, Novel, PATHOGENIC, PHLEBOVIRUS, PLATFORM, Platforms, sequence, therapeutic, therapeutic candidates, THEREOF, TICK, TICK-BORNE, TICKS, TWO, Vaccine, VACCINE VECTORS, Vector, Vector-based, Vector-borne, Vector-borne diseases, VETERINARY, VETERINARY vaccine, viral, virus, VLXXXX, VOXXXX, WBXXXX, WDXXXX, WFXXXX, WIXXXX, WJXXXX, XAXXXX, XCXXXX, XHXXXX, YAXXXX, YBXXXX, Zoo
Category(s): Collaboration Sought > Licensing, ResearchProducts > Antibodies, ResearchProducts > Research Equipment, Application > Research Materials, TherapeuticArea > Immunology, Application > Diagnostics, Application > Vaccines, Application > Therapeutics, TherapeuticArea > Infectious Disease, Application > Occupational Safety and Health, Application > Consumer Products
A Full-Length Infectious cDNA Clone of Zika Virus from the 2015 Epidemic in Brazil as a Genetic Platform for Studies of Virus-Host Interactions and Vaccine Development
An arthropod-borne virus, Zika virus (ZIKV), has recently emerged as a major human pathogen. Associated with complications during perinatal development and Guillain-Barré syndrome in adults, ZIKV raises new challenges for understanding the molecular determinants of flavivirus pathogenesis. This underscores the necessity for the development of a reverse...
Published: 7/25/2024   |   Inventor(s): Konstantin Tsetsarkin, Alexander Pletnev
Keywords(s): 2015, Brazil, cDNA, CLONE, DAXXXX, DBXXXX, DC5BXX, DC5XXX, DC6XXX, DCXXXX, DD1XXX, DDXXXX, Development, DXXXXX, Epidemic, FULL-LENGTH, Genetic, INFECTIOUS, INTERACTIONS, PLATFORM, STUDIES, Vaccine, virus, Virus-Host, Zika
Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Infectious Disease, Application > Vaccines, Application > Research Materials, Application > Diagnostics
Microfluidic and Organotypic Tumor Slice Culture Drug Testing Platform for Individualized Cancer Therapy
Application A drug combination screening/testing platform for individualized cancer therapy. Key Benefits Rapid screening of effective drug combination. Integrated tumor microenvironment. Identifying personalized therapy for individual cancer patient. Market Summary Traditional two-dimensional (2D) in vitro culture models for drug development...
Published: 7/30/2024   |   Inventor(s): Tobey John MacDonald, Anna Kenney, Abhinav Dey, YongTae (Tony) Kim
Keywords(s): Platform
Category(s): TechPub Algolia > Drug Discovery
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