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Tinker Tales: Interactive AI Storytelling for Early Learners

Application A hybrid tangible-digital storytelling platform designed to teach artificial intelligence (AI) literacy to children aged 5 through 8. Key Benefits Provides a hands-on, developmentally appropriate learning experience for young children, enhancing engagement and retention. Enables dynamic, real-time co-creation of stories, fostering...

Published: 4/22/2026 | Updated: 4/22/2026 | Inventor(s): Jinho Choi, Ikseon (Ike) Choi, Nayoung Choi

Keywords(s): Mobile Apps, Non-Therapeutics, Platform, Simulation, Training, and Modeling

Category(s): TechPub Algolia > Software

DNA EndosomaL Escape Vehicle Response (DELVR) as a Platform to Boost Antisense Oligonucleotide (ASO) Efficacy

Application A versatile delivery platform for antisense oligonucleotides (ASOs) enabling transient downregulation of protein expression. Key Benefits Broadly boost the efficacy of nucleic acid-based drugs. Drastic reduction in toxicity. DELVR strategy can rescue clinically tested ASOs that didn’t progress to FDA approval due to off-target...

Published: 4/22/2026 | Updated: 4/22/2026 | Inventor(s): Steven Narum, Khalid Salaita

Keywords(s): Gene Therapy and Editing, Nanoparticle Drug Delivery, Platform, Rare and Orphan Disease Treatments, Therapeutics

Category(s): TechPub Algolia > Micro and Nanotechnology

Next Gen Immune-Optimized Gene Delivery

Application An advanced gene therapy approach that improves therapeutic efficiency by protecting transgene expressing cells from host immune responses, through modulation of a key immune checkpoint pathway. Key Benefits Enhanced efficiency across viral and non-viral gene delivery systems, including AAV, lentivirus, LNPs, and electroporation. Enables...

Published: 3/11/2026 | Updated: 2/23/2026 | Inventor(s): Matthew (Matt) Gardner, Michael Kuipa, Abubakarr Koroma, Isai Leguizamo

Keywords(s): Biologics, Cell Therapy, Gene Therapy and Editing, Immunology and Inflammation Treatments, Oncology Treatments, Platform, Regenerative Medicine

Category(s): TechPub Algolia > Therapeutics

Non-invasive Diagnostic for Meningiomas

Application A non-invasive molecular diagnostic tool that reliably predicts the tumor characteristics and risk of recurrence of meningiomas. Key Benefits Combines meningioma gene expression data, construction of a gene interaction network, and tumor histology data to diagnose and predict clinical outcomes. Complete analytical handling from specimen...

Published: 1/28/2026 | Updated: 1/28/2026 | Inventor(s): Ali Alawieh, Youssef Ismail, Tomas Garzon-Muvdi

Keywords(s): Algorithm, AI, and Machine Learning, Biomarkers, Oncology Treatments, Personalized Medicine, Platform, Screening Assays

Category(s): TechPub Algolia > Diagnostics

Smartphone Diagnostic for Rapid Respiratory Virus Detection

Application Diagnostic and automatic surveillance platform to identify RSV, Influenza A, and COVID-19 in real-time. Key Benefits Rapid smartphone-based detection of multiple respiratory viruses in nasal swab, breath condensate, and saliva. Requires few reagents and no expensive equipment. Limit of detection on par with PCR and rapid readout. Enables...

Published: 2/5/2026 | Updated: 7/2/2024 | Inventor(s): Selma Piranej, Khalid Salaita

Keywords(s): COVID19, Molecular Diagnostics, Platform

Category(s): TechPub Algolia > Diagnostics

Next Generation L-Asparaginase Cancer Therapeutics

Application A humanized therapeutic L-asparaginase compound to treat acute lymphoblastic leukemia (ALL) and other cancers. Key Benefits Human‑aligned variants may reduce immunogenicity and systemic toxicity compared to current FDA‑approved asparaginase drugs. Opportunity to improve treatment outcomes by minimizing the severe hypersensitivity reactions...

Published: 4/10/2026 | Updated: 12/1/2023 | Inventor(s): Sunil Raikar, Christopher Doering, H. (Harold) Trent Spencer, Kristopher Knight, Harrison Brown

Keywords(s): Oncology Treatments, Pediatrics, Platform

Category(s): TechPub Algolia > Drug Discovery

Improving CAR T cell efficacy with Cytokine-Loaded Microparticles

Application Novel reagents for manufacturing of CAR T cells with improved characteristics. Key Benefits A multi-cytokine backpack particle that can be used during manufacturing process of CAR T treatments to improve their phenotype and efficacy. Preliminary data show the method can transduce primary healthy and patient T cells and promote CAR...

Published: 9/3/2025 | Updated: 4/5/2023 | Inventor(s): Sarwish Rafiq, Erik Dreaden, A K M Nawshad Hossian, Biaggio Uricoli

Keywords(s): Cell Therapy, Oncology Treatments, Platform, Production Methods

Category(s): TechPub Algolia > Micro and Nanotechnology

Liquid-hydrogel Hybrid Microfluidic Device

Application Measurement device for detecting of single-cell dynamics under environment perturbations or drug treatment. Key Benefits Fast determination of drug sensitivity. Long-term continuous cell-fate tracking. Time-lapse analysis of cell proliferation. Cell community analysis: intra-species interactions, inter-species interactions. Market...

Published: 1/20/2026 | Updated: 12/20/2022 | Inventor(s): Kyle Allison, Xin Fang, Devina Puri

Keywords(s): Medical Imaging (MRI, CT, Radiology), Microfluidics, Platform

Category(s): TechPub Algolia > Diagnostics, TechPub Algolia > Research Tools, TechPub Algolia > Medical Device

Intranasal Nebulizer with Disposable Drug Cartridge for Improved Delivery of Vaccines and Therapeutics

Intranasal delivery is a simple, inexpensive and needle-free route for administration of vaccines and therapeutics. This intranasal delivery technology, developed with Creare LLC., includes low-cost, disposable drug cartridges (DDCs) that mate with a durable hand-held device. The rechargeable-battery-powered device transmits ultrasonic energy to the...

Published: 8/13/2025 | Updated: 12/6/2022 | Inventor(s): James Barry, Nabil Elkouh, Mark Bagley, Darin Knaus, Robert Trabka, Eric Friets, James Norris, Mark Papania

Keywords(s): AB1XXX, AB3FXX, AB3GXX, AB3XXX, AB4XXX, Able, ABXXXX, AC1XXX, ACXXXX, AEROSOL, AEROSOL-GENERATING, AEROSOLIZATION, Aerosolized, AEROSOLS, AXXXXX, BACTERIA, Bacterial, BACTERIAL VACCINES, CARTRIDGE, CDC, CDC Docket Import, CDC Docket Import CDC Prosecuting, Chamber, COOLING, DB1XXX, DB2XXX, DB3XXX, DB4XXX, DB5XXX, DBXXXX, DC1XXX, DC2XXX, DC3XXX, DC4XXX, DC5BXX, DC5XXX, DC6XXX, DCXXXX, Delivery, DEVICE, Devices, Disposable, DRUG, Drug Delivery, DXXXXX, FUNGAL, HAND, Having, INSERT, Intranasal, Methods, NASAL, NEBULIZER, NIOSH-PRL, OID-NCIRD-DVD, PLATFORM, Platforms, Pulmonary, respiratory, Respiratory Diseases, respiratory INFECTION, System, SYSTEMS, therapeutic, therapeutic delivery, Vaccine, VACCINE DELIVERY, Vaccine Design, VACCINE DEVELOPMENT, VBXXXX, viral, viral vaccine, VJXXXX, VKXXXX, VLXXXX, VOXXXX, VPXXXX, WAXXXX, WFXXXX, WJXXXX, WKXXXX, WMXXXX, XDXXXX, YBXXXX, YCXXXX, YFXXXX

Category(s): Collaboration Sought > Licensing, Application > Occupational Safety and Health, Application > Medical Devices, Application > Diagnostics, Application > Vaccines, Application > Therapeutics, TherapeuticArea > Dental, TherapeuticArea > Infectious Disease, TherapeuticArea > Endocrinology, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Ophthalmology, Application > Consumer Products, TherapeuticArea > Oncology

Diagnostics, Vaccines, and Delivery-Vehicles Related to Novel Phlebovirus

This CDC invention relates to primers and probes that specifically hybridize with Heartland virus (HRTLDV), a unique member of the genus Phlebovirus. It further relates to polyclonal antibodies specific for HRTLDV proteins. Serological detection assays using HRTLDV nucleic acid molecules, proteins, probes, primers, and antibodies are provided. Importantly,...

Published: 4/24/2025 | Updated: 12/6/2022 | Inventor(s): Stuart Nichol, William Nicholson, Cynthia Goldsmith, Aubree Kelly, Laura McMullan

Keywords(s): AC4XXX, ACXXXX, ANTIBODY, ANTIGEN, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, Compositions, DA4BXX, DA4XXX, DAXXXX, DC1XXX, DC5BXX, DC5XXX, DCXXXX, DDXXXX, Delivery, delivery system, DEVELOPED, diagnostic, DXXXXX, GB2CXX, GB2XXX, GBXXXX, GCXXXX, GENE THERAPY, gene transfer, GXXXXX, heartland, heartland virus, Hospitalized, Identification, ISOLATES, Isolation, Methods, Missouri, Novel, PATHOGENIC, PHLEBOVIRUS, PLATFORM, Platforms, sequence, therapeutic, therapeutic candidates, THEREOF, TICK, TICK-BORNE, TICKS, TWO, Vaccine, VACCINE VECTORS, Vector, Vector-based, Vector-borne, Vector-borne diseases, VETERINARY, VETERINARY vaccine, viral, virus, VLXXXX, VOXXXX, WBXXXX, WDXXXX, WFXXXX, WIXXXX, WJXXXX, XAXXXX, XCXXXX, XHXXXX, YAXXXX, YBXXXX, Zoo

Category(s): Collaboration Sought > Licensing, ResearchProducts > Antibodies, ResearchProducts > Research Equipment, Application > Research Materials, TherapeuticArea > Immunology, Application > Diagnostics, Application > Vaccines, Application > Therapeutics, TherapeuticArea > Infectious Disease, Application > Occupational Safety and Health, Application > Consumer Products

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