Search Results - bacteria

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Compounds for Improved Psychological and Resilience Measures Associated with Physical Activity (UCLA Case No. 2022-272)
UCLA researchers from the Department of Medicine have identified microbiome and metabolic markers associated with high physical activity in an obese population, leading to possible therapies that may provide the positive effects of physical activity. BACKGROUND: It is known that physical activity has a multitude of beneficial effects on health. On...
Published: 11/18/2024   |   Inventor(s): Arpana Church
Keywords(s): Bacteria, Exercise, Gastroenterology & Digestive Disease, gut-brain axis, Human Gastrointestinal Tract, metabolomics, microbiome, MRI, Nutraceuticals / Probiotics, obesity, physical activity, prebiotics, Psychology
Category(s): Therapeutics > Gastroenterology, Therapeutics > Psychiatry And Mental Health, Therapeutics > Metabolism And Endocrinology
­GENERATION OF ANTIGEN-SPECIFIC T AND B CELLS USING ENGINEERED COMMENSALS
­GENERATION OF ANTIGEN-SPECIFIC T AND B CELLS USING ENGINEERED COMMENSALS Researchers at Stanford have developed methods to link antigenic or immunomodulatory molecules to bacterial surface proteins of commensal bacteria that result in a high immune response when applied to an epithelial surface of a mammal. Commensal microbiota reside primarily...
Published: 2/14/2024   |   Inventor(s): Michael Fischbach, Djenet Bousbaine, Christopher Barnes, Katherine Bauman, Yasmine Belkaid
Keywords(s): Antigen, Bacteria, Immunomodulator
Category(s): Technology Classifications > Biology
BACTERIA-ENGINEERED TO ELICIT ANTIGEN-SPECIFIC T-CELLS
­BACTERIA-ENGINEERED TO ELICIT ANTIGEN-SPECIFIC T-CELLS Researchers at Stanford have developed a new avenue for stimulating T effector and Treg immune cells in an antigen-specific manner. Commensal microbiota have been shown to functionally regulate the innate and adaptive immune systems and must establish distinct niches at barrier sites throughout...
Published: 10/6/2023   |   Inventor(s): Michael Fischbach, Kazuki Nagashima, Yiyin Chen, Djenet Bousbaine
Keywords(s): Autoimmune, Bacteria, T-Cell Activation
Category(s): Technology Classifications > Biology
­BACTERIA-ENGINEERED TO ELICIT ANTIGEN-SPECIFIC T-CELLS
­BACTERIA-ENGINEERED TO ELICIT ANTIGEN-SPECIFIC T-CELLS Researchers at Stanford have developed a new avenue for stimulating T effector and Treg immune cells in an antigen-specific manner. Commensal microbiota have been shown to functionally regulate the innate and adaptive immune systems and must establish distinct niches at barrier sites throughout...
Published: 10/6/2023   |   Inventor(s): Michael Fischbach, Kazuki Nagashima, Yiyin Chen
Keywords(s): Autoimmune, Bacteria, T-Cell Activation
Category(s): Technology Classifications > Biology
CHEMICALLY MODIFIED BACTERIAL PEPTIDOGLYCAN COMPOSITIONS AND USES THEREOF
CHEMICALLY MODIFIED BACTERIAL PEPTIDOGLYCAN COMPOSITIONS AND USES THEREOF Researchers at Stanford have developed a new microparticle vaccine scaffold for the development of immunogenic subunit vaccines. Vaccines are one of the most important biomedical advances of the 20th century. Protein vaccines, often referred to as subunit vaccines, have proved...
Published: 8/17/2023   |   Inventor(s): Peter Kim, Carolyn Bertozzi, Frances RodrÃguez-Rivera
Keywords(s): Adjuvant, Bacteria, Peptidoglycan, Vaccine
Category(s): Technology Classifications > Biology
2022-258 Deep Learning-Enabled Detection and Classification of Bacterial Colonies Using a Thin Film Transistor (TFT) Image Sensor
Summary: UCLA Researchers in the Department of Electrical and Computer Engineering have developed a thin-film transistor-based image sensor that can quantify and identify bacterial colony forming units (CFUs) with high accuracy using a deep-learning algorithm. Background: Bacterial infections are a leading cause of death every year in both developed...
Published: 7/19/2023   |   Inventor(s): Aydogan Ozcan, Yuzhu Li, Tairan Liu
Keywords(s): Antibacterial, Artificial Neural Network, Bacteria, Holography, Machine Learning, Magnetic Resonance Imaging Carotid Artery Stenosis, Thin-Film Transistor, Transistor
Category(s): Software & Algorithms, Life Science Research Tools, Life Science Research Tools > Screening Libraries, Materials, Materials > Nanotechnology, Materials > Semiconducting Materials, Life Science Research Tools > Cell Counting And Imaging
Compositions and Methods for Improved Lyme Disease Diagnosis
This CDC-developed technology entails novel compositions and methods related to the diagnosis of Lyme disease. Lyme disease, caused by the Borrelia burgdorferi bacterium, is the most common tick-borne infectious disease in the US and Europe. Diagnosis of Lyme disease is particularly challenging as symptoms often appear long after exposure. At present,...
Published: 10/28/2024   |   Inventor(s): Theresa Russell, Barbara Johnson
Keywords(s): BACTERIA, BORRELIA BURGDORFERI, BORRELLIA, BURGDORFERI, CDC Docket Import, CDC Docket Import CDC Prosecuting, Compositions, DA3XXX, DAXXXX, diagnostic, Diagnostic assay, diagnostic in vitro, Disease, DXXXXX, ivd, LYME, Methods, Relating, TICK, TICK-BORNE, TICKS, Vector-borne, Vector-borne diseases, VETERINARY, VJXXXX, VOXXXX, WBXXXX, WCXXXX, WDXXXX, WFXXXX, WIXXXX, WMXXXX, XCXXXX, YBXXXX, Zoonotic
Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Diagnostics, Application > Occupational Safety and Health, Application > Consumer Products, TherapeuticArea > Infectious Disease
Improved Botulism, Botulinum Neurotoxin Type-E Diagnostics
CDC researchers have improved upon a prior, HHS patented mass spectrometry-based Endopep-MS assay that is able to rapidly detect and differentiate all seven botulinum neurotoxin (BoNT) types A to G. This current improvement comprises the addition of two optimized substrate peptides that increases the assay's sensitivity,relative to prior substrates,...
Published: 10/28/2024   |   Inventor(s): Suzanne Kalb, John Barr, Dongxia Wang
Keywords(s): AAXXXX, ACXXXX, BACTERIA, Bacterial, Biodefense, Biodetection, Bolulinum, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA3XXX, DA5XXX, DAXXXX, DXXXXX, e, MASS SPECTROMETER, Mass spectrometry, Neurotoxin, Novel, Peptide, Recognizable, SUBSTRATES, toxin, TYPE, VBXXXX, VJXXXX, VKXXXX, VLXXXX, WAXXXX, WBXXXX, WCXXXX, WFXXXX, WIXXXX, WMXXXX, XCXXXX, XDXXXX, XHXXXX, YBXXXX
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Therapeutics, Application > Vaccines, Application > Consumer Products, Application > Non-Medical Devices, Application > Medical Devices, ResearchProducts > Research Equipment, Application > Research Materials, Application > Diagnostics, Application > Occupational Safety and Health
Intranasal Nebulizer with Disposable Drug Cartridge for Improved Delivery of Vaccines and Therapeutics
Intranasal delivery is a simple, inexpensive and needle-free route for administration of vaccines and therapeutics. This intranasal delivery technology, developed with Creare LLC., includes low-cost, disposable drug cartridges (DDCs) that mate with a durable hand-held device. The rechargeable-battery-powered device transmits ultrasonic energy to the...
Published: 10/28/2024   |   Inventor(s): James Barry, Nabil Elkouh, Mark Bagley, Darin Knaus, Robert Trabka, Eric Friets, James Norris, Mark Papania
Keywords(s): AB1XXX, AB3FXX, AB3GXX, AB3XXX, AB4XXX, Able, ABXXXX, AC1XXX, ACXXXX, AEROSOL, AEROSOL-GENERATING, AEROSOLIZATION, Aerosolized, AEROSOLS, AXXXXX, BACTERIA, Bacterial, BACTERIAL VACCINES, CARTRIDGE, CDC, CDC Docket Import, CDC Docket Import CDC Prosecuting, Chamber, COOLING, DB1XXX, DB2XXX, DB3XXX, DB4XXX, DB5XXX, DBXXXX, DC1XXX, DC2XXX, DC3XXX, DC4XXX, DC5BXX, DC5XXX, DC6XXX, DCXXXX, Delivery, DEVICE, Devices, Disposable, DRUG, Drug Delivery, DXXXXX, FUNGAL, HAND, Having, INSERT, Intranasal, Methods, NASAL, NEBULIZER, NIOSH-PRL, OID-NCIRD-DVD, PLATFORM, Platforms, Pulmonary, respiratory, Respiratory Diseases, respiratory INFECTION, System, SYSTEMS, therapeutic, therapeutic delivery, Vaccine, VACCINE DELIVERY, Vaccine Design, VACCINE DEVELOPMENT, VBXXXX, viral, viral vaccine, VJXXXX, VKXXXX, VLXXXX, VOXXXX, VPXXXX, WAXXXX, WFXXXX, WJXXXX, WKXXXX, WMXXXX, XDXXXX, YBXXXX, YCXXXX, YFXXXX
Category(s): Collaboration Sought > Licensing, Application > Occupational Safety and Health, Application > Medical Devices, Application > Diagnostics, Application > Vaccines, Application > Therapeutics, TherapeuticArea > Dental, TherapeuticArea > Infectious Disease, TherapeuticArea > Endocrinology, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Ophthalmology, Application > Consumer Products, TherapeuticArea > Oncology
Intranasal Dry Powder Inhaler for Improved Delivery of Vaccines and Therapeutics
This Intranasal Dry Powder Inhaler (DPI), developed with Creare, Inc., allows low-cost delivery of powder vaccines. Nasal delivery has numerous advantages compared to traditional injected vaccines, including: 1) safe, needle-less administration by minimally-trained staff or patient; 2) better protection due to mucosal and cross-protection; and 3) decreased...
Published: 10/28/2024   |   Inventor(s): James Barry, Darin Knaus, Edward Moynihan, Eric Friets, Mark Bagley, Mark Papania
Keywords(s): AB1XXX, AB3FXX, AB3GXX, ABXXXX, Agents, AXXXXX, BACTERIA, Bacterial, BACTERIAL VACCINES, Biodefense, biosecurity, bioterrorism, Bioterrorist, CDC Docket Import, CDC Docket Import CDC Prosecuting, Child safety device, CHILDHOOD, Children, DB1XXX, DB2XXX, DB3XXX, DB4AXX, DB4BXX, DB4XXX, DB5XXX, DBXXXX, DC1XXX, DC2XXX, DC3XXX, DC4XXX, DC5XXX, DC6XXX, DCXXXX, Delivery, delivery system, DEVELOPED, DEVELOPING, DEVICE, Devices, Disposable, DISPOSAL, Dry, DXXXXX, Field, Field-usable, FUNGAL, Intranasal, MEASLES, NASAL, Needle, OID-NCIRD-DVD, Portable, POWDER, Prevention, respiratory, SAFETY, SELF-ADMINISTRATION, Single-use, System, therapeutic delivery, treatment, VACCINATION, Vaccinations, VACCINE DELIVERY, vaccines, VBXXXX, viral vaccine, VJXXXX, VKXXXX, VLXXXX, VOXXXX, WAXXXX, WKXXXX, WMXXXX, XDXXXX, YBXXXX, YFXXXX
Category(s): Collaboration Sought > Licensing, Application > Diagnostics, Application > Medical Devices, Application > Vaccines, TherapeuticArea > Infectious Disease, Application > Non-Medical Devices, Application > Consumer Products, Application > Therapeutics
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