Search Results - sarwish+rafiq

2 Results Sort By:
Improving CAR T cell efficacy with Cytokine-Loaded Microparticles
Application Novel reagents for manufacturing of CAR T cells with improved characteristics. Key Benefits A multi-cytokine backpack particle that can be used during manufacturing process of CAR T treatments to improve their phenotype and efficacy. Preliminary data show the method can transduce primary healthy and patient T cells and promote CAR...
Published: 11/20/2024   |   Inventor(s): Sarwish Rafiq, Erik Dreaden, A K M Nawshad Hossian, Biaggio Uricoli
Keywords(s): Oncology, Platform
Category(s): TechPub Algolia > Micro and Nanotechnology
Interleukin-37 to Enhance Effectiveness of CAR T-cell Therapy
­ Application IL-37-expressing CAR T-cells to treat B-cell acute lymphoblastic leukemia. Key Benefits Boosts the function of aged T-cells. Enhances the effectiveness of CAR T-cell therapy. Therapeutic potential to overcome aging-associated immune-senescence. Potent suppressor of chronic inflammation or pro-inflammatory cytokines. Market...
Published: 10/17/2024   |   Inventor(s): Curtis Henry, Sunil Raikar, Sarwish Rafiq
Keywords(s): Immunology/Inflammation, Oncology
Category(s): TechPub Algolia > Therapeutics