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DNA EndosomaL Escape Vehicle Response (DELVR) as a Platform to Boost Antisense Oligonucleotide (ASO) Efficacy
Application A versatile delivery platform for antisense oligonucleotides (ASOs) enabling transient downregulation of protein expression. Key Benefits Broadly boost the efficacy of nucleic acid-based drugs. Drastic reduction in toxicity. DELVR strategy can rescue clinically tested ASOs that didn’t progress to FDA approval due to off-target...
Published: 4/22/2026   |   Updated: 4/22/2026   |   Inventor(s): Steven Narum, Khalid Salaita
Keywords(s): Gene Therapy and Editing, Nanoparticle Drug Delivery, Platform, Rare and Orphan Disease Treatments, Therapeutics
Category(s): TechPub Algolia > Micro and Nanotechnology