Search Results - sunil+raikar

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Drug Platform for L-Asparaginases for the Treatment of Leukemias
Application A novel humanized therapeutic L-asparaginase compound to treat acute lymphoblastic leukemia (ALL) and other cancers. Key Benefits A novel drug discovery platform for developing asparaginase-based compounds to treat leukemias and other cancers. The derivatives could exhibit less immunogenicity and systemic toxicity than FDA-approved...
Published: 11/20/2024   |   Inventor(s): Sunil Raikar, Christopher Doering, H. (Harold) Trent Spencer, Kristopher Knight, Harrison Brown
Keywords(s): Oncology, Pediatrics, Platform
Category(s): TechPub Algolia > Drug Discovery
Interleukin-37 to Enhance Effectiveness of CAR T-cell Therapy
­ Application IL-37-expressing CAR T-cells to treat B-cell acute lymphoblastic leukemia. Key Benefits Boosts the function of aged T-cells. Enhances the effectiveness of CAR T-cell therapy. Therapeutic potential to overcome aging-associated immune-senescence. Potent suppressor of chronic inflammation or pro-inflammatory cytokines. Market...
Published: 10/17/2024   |   Inventor(s): Curtis Henry, Sunil Raikar, Sarwish Rafiq
Keywords(s): Immunology/Inflammation, Oncology
Category(s): TechPub Algolia > Therapeutics
Galectin-9 Directed CAR T-cells for Overcoming Resistance to Chemotherapy in Hematological Malignancies
Application Anti-human Galectin-9-directed chimeric antigen receptor (CAR) T-cells for treatment of hematological malignancies (B-ALL, T-ALL, and DLBCL) in normal, overweight, and obese patients. Key Benefits Can be used as a stand-alone or in-combination product to treat patients with hematological malignancies, particularly overweight and obese...
Published: 9/26/2024   |   Inventor(s): Curtis Henry, Miyoung (Mi-Young) Lee, Sunil Raikar, Jamie Hamilton, Anthony Ross
Keywords(s): Antibody, Cell/Gene Therapy, Oncology, Pediatrics
Category(s): TechPub Algolia > Therapeutics, TechPub Algolia > Drug Discovery