Search Results - khalid+salaita

21 Results Sort By:
Smartphone Diagnostic for Rapid Respiratory Virus Detection
Application Diagnostic and automatic surveillance platform to identify RSV, Influenza A, and COVID-19 in real-time. Key Benefits Rapid smartphone-based detection of multiple respiratory viruses in nasal swab, breath condensate, and saliva. Requires few reagents and no expensive equipment. Limit of detection on par with PCR and rapid readout. Enables...
Published: 8/22/2024   |   Inventor(s): Selma Piranej, Khalid Salaita
Keywords(s): COVID19, Microbiology/Infectious Diseases, Platform, Respiratory
Category(s): TechPub Algolia > Diagnostics
Enhanced Delivery and Efficacy of Antisense Drugs via Covalently Linked Nanodisc Scaffolds
Application A synthetic nanodisc (ND) scaffold for delivering antisense oligonucleotides (ASOs) for the treatment of disease. Key Benefits Improved cellular uptake and protein suppression using antisense oligos. Longer ASO half-life compared to other ASO delivery methods. Potential to overcome the delivery and efficacy challenges using ASOs for...
Published: 8/22/2024   |   Inventor(s): Khalid Salaita, Radhika Sharma
Keywords(s): Biomaterials, Cardiovascular, Chemistry, Oncology
Category(s): TechPub Algolia > Therapeutics, TechPub Algolia > Drug Discovery, TechPub Algolia > Micro and Nanotechnology
Tension-activated Cell Tagging (TaCT)
Application A tool that measures cellular mechanical forces using flow cytometry. Key Benefits A fluorescently labeled approach based on the magnitude of molecular forces transmitted through cell adhesion receptors for evaluating mechanical forces in cells. A prototype has been developed showing proof -of-concept via the ability to determine mechanical...
Published: 7/30/2024   |   Inventor(s): Rong Ma, Khalid Salaita
Keywords(s): Assay
Category(s): TechPub Algolia > Research Tools
Using Hetero-multivalent DNA-functionalized Materials to Detect Genetic Mutations
Application Improving diagnostic accuracy using hetero-multivalent DNA-functionalized materials for disease targets containing one or more genetic mutations. Key Benefits Tunable oligos increase specificity and cooperative binding to the disease target of interest. Distinguishes between cis- and trans mutations. Identifies different strains of...
Published: 7/30/2024   |   Inventor(s): Brendan Deal, Khalid Salaita, Rong Ma, James Kindt
Keywords(s): COVID19, Genetic Disorders
Category(s): TechPub Algolia > Micro and Nanotechnology, TechPub Algolia > Diagnostics
Non-invasive Probes to Determine Efficacy of Cancer Therapies
Application A real-time, non-invasive probe to determine the efficacy of cancer immunotherapies. Key Benefits Determines immunotherapy success in patients. CAR cells can be tested before putting it back in the patients. Simple diagnostic with readout in 30 minutes compared to 2-3 days. Market Summary Lymphoblastic leukemia is one of the most...
Published: 7/30/2024   |   Inventor(s): Anna Kellner, Khalid Salaita, Curtis Henry
Keywords(s): Oncology, Pediatrics
Category(s): TechPub Algolia > Diagnostics
Mobile Phone Diagnostic for COVID-19
Application Diagnostic and automatic surveillance to identify COVID-19 via smartphone in real-time. Key Benefits Provides real-time, rapid results. Autonomous process. Device does not require RNA isolation or amplification for viral detection. Market Summary Coronavirus (COVID-19) is an infectious disease that causes severe acute respiratory...
Published: 7/30/2024   |   Inventor(s): Khalid Salaita, Alisina Bazrafshan, Selma Piranej
Keywords(s): COVID19
Category(s): TechPub Algolia > Diagnostics
Antisense Oligonucleotides Therapeutics Targeting Specific Tissues or Cells
Application Antisense oligonucleotide (ASO) therapies for the treatment of rare diseases and cancer. Key Benefits Novel approach to ASO therapeutics that potentially improve tissue/cell targeting capabilities. Increases the efficacy of ASOs while decrease off-target toxicity. Potential to treat a variety of genetic diseases such as cancer, blood...
Published: 8/22/2024   |   Inventor(s): Jiahui Zhang, Khalid Salaita, Hanjoong Jo
Keywords(s): Hematology/Blood Products, Oncology, Rare/Orphan Diseases
Category(s): TechPub Algolia > Therapeutics
Chameleon-Inspired Strain-Accommodating Smart Skin
Application A flexible smart skin that changes its color in response to heat or sunlight. Key Benefits Strain-accommodating. Thermal and photothermal responsive. Light responsive. Highly stretchable. Market Summary Hydrogels are water-insoluble, three-dimensional networks of polymer chains capable of holding large amounts of water. They are...
Published: 7/30/2024   |   Inventor(s): Khalid Salaita, Yixiao Dong
Keywords(s): Biomaterials, Chemistry
Category(s): TechPub Algolia > Micro and Nanotechnology
A Method of Using Responsive Micro and Sub-micro Scale Polymer Particles for Mechanical Manipulation of Molecules
Application A method to study the mechanical/controlled unfolding of biomolecules using a polymer force clamp (PFC). Key Benefits Particles can be immobilized onto virtually any type of support. Particles can also be functionalized with a variety of small-molecule, peptide and protein ligands. Ability to have multiple PFC’s measuring associated...
Published: 8/22/2024   |   Inventor(s): Hanquan Su, Khalid Salaita
Keywords(s):  
Category(s): TechPub Algolia > Research Tools, TechPub Algolia > Micro and Nanotechnology
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 7/30/2024   |   Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li
Keywords(s):  
Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
1 2 3