Search Results - vaccine+development

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Polypeptides and Methods for Enhancing and Balancing Monovalent or Multivalent Flavivirus Vaccines
CDC researchers have developed a potent immunogenic enhancer polypeptide useful for improving flavivirus vaccines. Flaviviruses such as dengue virus (1, 2, 3 and 4), Japanese encephalitis virus, Murray Valley encephalitis virus, St. Louis encephalitis virus, yellow fever virus and tick-borne encephalitis virus are a great burden on public health. ...
Published: 10/28/2024   |   Inventor(s): Holly Hughes, Gwong-Jen Chang
Keywords(s): ADJUSTMENT, adjuvant, Adjuvant-like, BCXXXX, Boost, BOOSTING, CD4, CDC Docket Import, CDC Docket Import CDC Prosecuting, Cell, DB4BXX, DB4XXX, DC1XXX, DC5BXX, DC5XXX, DCXXXX, DDXXXX, DENGUE, DENGUE FEVER, Dengue Vaccine, Dengue-1, Dengue-2, Dengue-Like, DXXXXX, Epitope, Flavivirus, FLAVIVIRUSES, Identification, in vivo, JAPANESE ENCEPHALITIS VIRUS, Listed LPM Houze as of 4/15/2015, Mosquito, Mosquitoes, Nile, OID-NCEZID-DVBD, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, PRIMER, T, THEREOF, Tick-Bone, TICK-BORNE, UBXXXX, Vaccine, Vaccine Design, VACCINE DEVELOPMENT, VBXXXX, Vector-borne, Vector-borne diseases, virus, VLXXXX, VOXXXX, WAXXXX, West, WIXXXX, WJXXXX, WMXXXX, XCXXXX, YBXXXX, YCXXXX
Category(s): Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Rare / Neglected Diseases, Application > Vaccines, Application > Therapeutics, Application > Research Materials, Application > Consumer Products, TherapeuticArea > Infectious Disease
Select M. tuberculosis Peptides as Mucosal Vaccines Against Pulmonary Tuberculosis
This CDC-developed technology relates to novel vaccines or boosters directed against pulmonary tuberculosis. There is currently only a single vaccine against tuberculosis, the (Bacillus Calmette-Guérin) BCG vaccine. Reports suggest widely variable effectiveness for the BCG vaccine and that BCG administration has very limited success against prevention...
Published: 10/28/2024   |   Inventor(s): Bonnie Plikaytis, Thomas Shinnick, Rama Amara, Mani Cheruvu, Suraj Sable
Keywords(s): Alaine, ANTIGEN, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA3XXX, DAXXXX, DC1XXX, DC4XXX, DCXXXX, DXXXXX, Identification, Mucosal, MYCOBACTERIUM, OID-NCHHSTP-DTE, PROLINE, Pulmonary, respiratory, Respiratory Diseases, respiratory INFECTION, Rich, TUBERCULOSIS, Vaccine, VACCINE DEVELOPMENT, VJXXXX, VPXXXX, WIXXXX, WJXXXX, XCXXXX, XEXXXX, XHXXXX, YBXXXX, YCXXXX
Category(s): Collaboration Sought > Licensing, Application > Therapeutics, Application > Vaccines, Application > Research Materials, TherapeuticArea > Endocrinology, TherapeuticArea > Oncology, Application > Diagnostics, TherapeuticArea > Dental, TherapeuticArea > Ophthalmology, TherapeuticArea > Cardiology, TherapeuticArea > Infectious Disease, ResearchProducts > Research Equipment
Intranasal Nebulizer with Disposable Drug Cartridge for Improved Delivery of Vaccines and Therapeutics
Intranasal delivery is a simple, inexpensive and needle-free route for administration of vaccines and therapeutics. This intranasal delivery technology, developed with Creare LLC., includes low-cost, disposable drug cartridges (DDCs) that mate with a durable hand-held device. The rechargeable-battery-powered device transmits ultrasonic energy to the...
Published: 10/28/2024   |   Inventor(s): James Barry, Nabil Elkouh, Mark Bagley, Darin Knaus, Robert Trabka, Eric Friets, James Norris, Mark Papania
Keywords(s): AB1XXX, AB3FXX, AB3GXX, AB3XXX, AB4XXX, Able, ABXXXX, AC1XXX, ACXXXX, AEROSOL, AEROSOL-GENERATING, AEROSOLIZATION, Aerosolized, AEROSOLS, AXXXXX, BACTERIA, Bacterial, BACTERIAL VACCINES, CARTRIDGE, CDC, CDC Docket Import, CDC Docket Import CDC Prosecuting, Chamber, COOLING, DB1XXX, DB2XXX, DB3XXX, DB4XXX, DB5XXX, DBXXXX, DC1XXX, DC2XXX, DC3XXX, DC4XXX, DC5BXX, DC5XXX, DC6XXX, DCXXXX, Delivery, DEVICE, Devices, Disposable, DRUG, Drug Delivery, DXXXXX, FUNGAL, HAND, Having, INSERT, Intranasal, Methods, NASAL, NEBULIZER, NIOSH-PRL, OID-NCIRD-DVD, PLATFORM, Platforms, Pulmonary, respiratory, Respiratory Diseases, respiratory INFECTION, System, SYSTEMS, therapeutic, therapeutic delivery, Vaccine, VACCINE DELIVERY, Vaccine Design, VACCINE DEVELOPMENT, VBXXXX, viral, viral vaccine, VJXXXX, VKXXXX, VLXXXX, VOXXXX, VPXXXX, WAXXXX, WFXXXX, WJXXXX, WKXXXX, WMXXXX, XDXXXX, YBXXXX, YCXXXX, YFXXXX
Category(s): Collaboration Sought > Licensing, Application > Occupational Safety and Health, Application > Medical Devices, Application > Diagnostics, Application > Vaccines, Application > Therapeutics, TherapeuticArea > Dental, TherapeuticArea > Infectious Disease, TherapeuticArea > Endocrinology, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Ophthalmology, Application > Consumer Products, TherapeuticArea > Oncology
Respiratory Syncytial Virus (RSV) Vaccines Based on Promoter-Proximate Attenuation
Available for licensing and commercial development is a patent estate and related biological materials for producing therapeutic or prophylactic vaccines against Respiratory Syncytial Virus (RSV). The claimed vaccine strategy relates to the engineering and creation of live-attenuated RSV vaccine candidates by shifting the position of one or more viral...
Published: 10/28/2024   |   Inventor(s): Peter Collins, Brian Murphy, Ursula Buchholz, Stephen Whitehead, Christine Krempl
Keywords(s): ATTENUATE, Attenuated, ATTENUATING, ATTENUATION, Chromosome 7, monosomy, DC5BXX, DC5XXX, DCXXXX, Deletion 7, DXXXXX, GENES, Noonan syndrome, NS1, Promoter-proximal, RSV, RSV virus, RSV/PIV, Syncytial, Vaccine, Vaccine Design, VACCINE DEVELOPMENT, VACCINE VECTORS, vaccines, virus
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Vaccines
Nanoparticle RNA Vaccine That Targets Slow-Cycling, Treatment-Resistant Cancer
Activates T-Cell Recognition of Tumor-Initiating Stem Cells in Mouse Model of Glioma This nanoparticle vaccine targets the slow-cycling, treatment-resistant, cancer stem cells to improve efficiency of anti-cancer drugs, thereby improving disease prognosis. Despite major developments in the field of anti-cancer therapies, tumor recurrence and metastasis...
Published: 2/13/2024   |   Inventor(s): Elias Sayour, Loic Deleyrolle, Hector Mendez-Gomez, Sadeem Qdaisat, Duane Mitchell
Keywords(s): Cancer, cancer stem cells, Immunotherapy, Nanoparticles, Vaccine development
Category(s): Technology Classifications > Human Health Care > Therapeutics