Search Results - immunology+and+inflammation+treatments

34 Results

Sort By:

Application An advanced gene therapy approach that improves therapeutic efficiency by protecting transgene expressing cells from host immune responses, through modulation of a key immune checkpoint pathway. Key Benefits Enhanced efficiency across viral and non-viral gene delivery systems, including AAV, lentivirus, LNPs, and electroporation. Enables...

Published: 2/23/2026 | Inventor(s): Matthew (Matt) Gardner, Michael Kuipa, Abubakarr Koroma, Isai Leguizamo

Keywords(s): Biologics, Cell Therapy, Gene Therapy and Editing, Immunology and Inflammation Treatments, Oncology Treatments, Platform, Regenerative Medicine

Category(s): TechPub Algolia > Therapeutics

Cell Line for Generating Nonhuman Primate T Cells

Application Cell line for efficient in vitro differentiation of rhesus macaque-specific T cells from hematopoietic stem and progenitor cells. Key Benefits Replaces need for primary rhesus macaque thymus tissue. Improves differentiation efficiency and reduces media requirements compared to existing methods. Yields CD4+ and CD8+ T cells, double-positive...

Published: 1/20/2026 | Inventor(s): Sheikh Rahman

Keywords(s): 3D in vitro Models, Animal Model, Cell Lines and Organoids, Immunology and Inflammation Treatments

Category(s): TechPub Algolia > Research Tools

Molecules Targeting Inflammatory Signaling

Application A group of small molecules for treating central and peripheral diseases associated with inflammation. Key Benefits Applicable to a wide variety of central nervous system and peripheral diseases. Can bypass side effects of existing therapeutics targeting similar inflammatory pathways. High target selectivity and aqueous solubility. Capability...

Published: 2/24/2026 | Inventor(s): Raymond (Ray) Dingledine, Radhika Amaradhi, Shabber Mohammed, Thota Ganesh

Keywords(s): Immunology and Inflammation Treatments, Neurology and Pain Treatments, Oncology Treatments, Small Molecule, Women's Health

Category(s): TechPub Algolia > Drug Discovery, TechPub Algolia > Therapeutics

MVA and DNA Based SARS-CoV-2 Vaccines

Application Modified Vaccinia virus Ankara (MVA)- and deoxyribonucleic acid (DNA)-based vaccine for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Key Benefits Safety profile is known. Demonstrated antiviral activity against related Coronaviruses. Single dose of vaccination was shown to be effective against related Coronaviruses...

Published: 1/20/2026 | Inventor(s): Rama Rao Amara, Sailaja Gangadhara

Keywords(s): Biologics, COVID19, DNA and RNA Vaccines, Immunology and Inflammation Treatments, Microbiology and Infectious Disease Treatments

Category(s): TechPub Algolia > Vaccines

Vaccine-pulsed Dendritic Cells as a Treatment for Aggressive Breast Cancers

Application Immunotherapy for HER2+ and triple-negative breast cancer. Key Benefits Autologous vaccine comprising patient-specific tumor antigens and immune stimulatory components against aggressive breast cancers. Prepared outside of the body and then administered to patients. Preclinical data indicate treatment decreases tumor growth and improves...

Published: 1/20/2026 | Inventor(s): Periasamy (Selva) Selvaraj, Luis Munoz, Ramireddy Bommireddy, Christopher Pack, Shaker Reddy, Sampath Ramachandiran

Keywords(s): Immunology and Inflammation Treatments, Oncology Treatments, Women's Health

Category(s): TechPub Algolia > Therapeutics

Vital Sign Trajectory Algorithm

Application A precision medicine algorithm that reduces mortality in sepsis patients by individualizing and targeting specific therapies to specific patients. Key Benefits An algorithm that uses bedside routine vital signs to optimize the precision treatment of sepsis. Clinical data show the ability of the algorithm to identify a subset of patients...

Published: 2/13/2025 | Inventor(s): Sivasubramanium (Siva) Bhavani

Keywords(s): Algorithm, AI, and Machine Learning, Immunology and Inflammation Treatments

Category(s): TechPub Algolia > Software

Improving Pediatric Asthma Management for Urban Families

Application Home-based family psychoeducational intervention for low-income children with persistent asthma. Key Benefits Medical and psychosocial needs of patients and family members can be addressed simultaneously. Significantly improved asthma management and caregiver stress in randomized controlled clinical trial. Market Summary Asthma...

Published: 2/13/2025 | Inventor(s): Marianne Celano, Lisa Kobrynski, Chanda Holsey

Keywords(s): Healthcare Professional Education and Training, Immunology and Inflammation Treatments, Pediatrics, Respiratory Treatments

Category(s): TechPub Algolia > Therapeutics

Methods for Enhancing MSC Therapeutic Potential for Treatment of Osteoarthritis by Measuring and Targeting Intracellular Pathways

Application Highly transformative new strategy to enhance mesenchymal stromal cell consistency and efficacy for taking MSC therapies to clinical stage. Key Benefits Currently there is no method to determine if an MSC donor line will be therapeutically effective. Provides a point of use assay in the clinical setting which can determine MSC efficacy...

Published: 2/5/2026 | Inventor(s): Nick Willett, Levi Wood, Jay McKinney

Keywords(s): Cell Therapy, Immunology and Inflammation Treatments

Category(s): TechPub Algolia > Research Tools, TechPub Algolia > Therapeutics

Novel Piperidine-Amide Derivatives as CXCR4 Modulators

Application A new class of CXCR4 modulators for metastasis and inflammation. Key Benefits Selective for only one allosteric site on CXCR4. Lower adverse effects. Market Summary Activation of the CXCR4 receptor triggers multiple signaling pathways that orchestrate cell migration, hematopoiesis and cell homing, and retention in the bone...

Published: 10/15/2025 | Inventor(s): Hyunsuk Shim, Yoon Hyeun Oum

Keywords(s): Immunology and Inflammation Treatments, Oncology Treatments, Small Molecule

Category(s): TechPub Algolia > Therapeutics

Targeted Immunotherapy for KRAS-Driven Cancers

Application Targeted immunotherapy and companion biosensing approach for cancers harboring the KRASG12V mutation. Key Benefits First-in-class therapeutic strategy specifically designed for KRASG12V-positive cancers. Addresses a significant unmet need in oncology where no approved KRASG12V-targeted therapies currently exist. Restores the body’s...

Published: 2/23/2026 | Inventor(s): Haian Fu, Cong Tang, Xiulei Mo

Keywords(s): Drug Target Identification, Enzyme and Protein Research, Immunology and Inflammation Treatments, Oncology Treatments

Category(s): TechPub Algolia > Drug Discovery, TechPub Algolia > Therapeutics

1 2 3 4