Search Results - device

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eDentin- a tissue engineered reparative dentin
Summary Current dental restoration materials trigger immune responses and poorly replicate the natural structure of the tooth, which delays the healing process. The current technology is a novel biomaterial that more closely mimics natural dentin and thereby allows for more efficient healing of the tooth. Technology Overview Cement-based materials...
Published: 6/21/2024   |   Inventor(s): Luiz Bertassoni, Cristiane Miranda Franca
Keywords(s): Dental, Device, Device - Other
Category(s): Dental, Device
Peptide Hydrogels for Rate-Controlled Delivery of Therapeutics
Abstract: Hydrogels represent an attractive controlled drug-delivery system that have been used in various clinical applications, such as: tissue engineering for wound healing, surgical procedures, pain management, cardiology, and oncology. High-water content of hydrogels confers tissue-like physical properties and the crosslinked fibrillar network...
Published: 4/8/2024   |   Inventor(s): Joel Schneider, Stephen Miller, Yuji Yamada, Steven Tau, Julie Hixon, Wenqing Li, Caroline Andrews, Scott Walsh
Keywords(s): DEVICE, IL-7, Nanoparticle, Peptide, Peptide-based Hydrogel, Protein, Schneider, small molecule, T Cell Enhancer, Whole Cell Delivery System
Category(s): TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Infectious Disease, Collaboration Sought > Licensing, TherapeuticArea > Immunology
Eye Tracking Application in Computer Aided Diagnosis and Image Processing in Radiology
Abstract: Medical imaging is an important resource for early diagnostic, detection, and effective treatment of cancers. However, the screening and review processes for radiologists have been shown to overlook a certain percentage of potentially cancerous image features. Such review errors may result in misdiagnosis and failure to identify tumors. These...
Published: 4/8/2024   |   Inventor(s): Bradford Wood, Haydar Celik, Ulas Bagci, Ismail Turkbey
Keywords(s): CAD, cc, Clinical Center, Computer Aided Diagnostics, DEVICE, Eye tracking, Image Processing, National Institutes of Health, NIH, Radiology, software, WOOD
Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Cardiology, Collaboration Sought > Licensing, Application > Software / Apps, TherapeuticArea > Oncology
A Specialized Tissue Collection Device for the Preservation and Transportation of Needle Biopsies
Abstract: The ability to hold and transport tissue, especially needle biopsies in a pre-defined and controlled environment is critical for the preservation of biopsy samples in downstream analytic applications. Currently, tissue specimens are placed in open containers with variable, poorly controlled solutions applied to them, often in less than sterile...
Published: 4/8/2024   |   Inventor(s): Stephen Hewitt, Robert Star, Hiroshi Kijoma, Jeffrey Hanson, Armando Filie, Russell Bandle
Keywords(s): COLLECTION, DEVICE, FIXATION, Hewitt, KIDNEY, liver, LUNG, Needle Biopsy, PANCREAS, PRESERVATION, STERILE, Storage, Tissue, Transportation
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Medical Devices, Collaboration Sought > Collaboration, Application > Non-Medical Devices
Single Cell In-Situ Extraction with Intact 3D Morphology from Formalin Fixed Paraffin Embedded (FFPE) Tissues
FFPE is a well-established and widely used method for preservation and histological analysis of tissue samples. DNA/RNA/and Proteins can be extracted from FFPE samples, but generally lack single cell resolution and completely lack 3D spatial resolution. Enabling 3D resolution allows the correlation of morphology to information like gene expression,...
Published: 4/25/2023   |   Inventor(s): David Richardson, Thai Tran, Dmitry Derkach, Colleen Ziegler
Keywords(s): Bioanalysis, Biological Cell Manipulation, Bio-Technology, Cancer, Device, Diagnostics, Gene Expression, Genomics, Proteomics, In situ, Molecular Diagnostics, Single-cell analysis
Category(s): Bioanalytical Assays, Chemistries & Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools
Origami-Inspired Wearable Robot for Trunk Support
A variety of rigid exoskeletons have been developed for improving mobility over the decades. High forces and torques provided by those rigid exoskeletons assist the ankle, hip and/or knee, facilitating activities such as walking or lifting heavy objects. However, due to the complexity of the human musculoskeletal system, adjusting and aligning human...
Published: 2/24/2023   |   Inventor(s): Daniel Aukes, Dongting Li
Keywords(s): Assistive Technology, Device, Materials and Electronics, Mechanical and Manufacturing, Robotics
Category(s): Applied Technologies, Physical Science
Assistive Device to Encode Spatial Information for Blind Navigation in a Tactile Format
­Visually impaired individuals often rely on assistive devices that attempt to encode spatial information into other means such as audio or tactile signals. However, challenges in implementation and interpretation of spatial information still exist. For instance, many existing devices still provide limited information to a user that the user must...
Published: 2/23/2023   |   Inventor(s): Troy McDaniel, Yatiraj Shetty, Shubham Gharat
Keywords(s): Assistive Technology, Detection, Device, Medical Devices and Imaging, Tactile
Category(s): Applied Technologies, Physical Science
Sensor for Real-time Detection of Plasma Metabolites Levels for the Diagnosis and Care of Metabolic Disorders
This technology includes the development of devices capable of real-time evaluation of metabolite levels for the treatment of numerous metabolic disorders, including hyperammonemia and aminoacidopathies. Currently, the monitoring of metabolite levels is done in a hospital setting with specialized mass spectrometry instrumentation. As a consequence,...
Published: 7/25/2024   |   Inventor(s): Adam Behrens, Peter Kofinas, Marshell Summar, Juan Luque-Cabrera, Gary Cunningham, Juan Marugan, Anton Simeonov, Omar Ayyub
Keywords(s): Detection, DEVICE, Listed LPM Tong as of 4/15/2015, MECHANICAL, METABOLITES, Metabolites., PLASMA, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, REAL, SENSOR, TIME, VPXXXX, WBXXXX, WFXXXX, WIXXXX, XCXXXX, XDXXXX
Category(s): TherapeuticArea > Endocrinology, TherapeuticArea > Dental, Application > Non-Medical Devices, TherapeuticArea > Ophthalmology, Application > Consumer Products, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, TherapeuticArea > Infectious Disease, Application > Medical Devices, Application > Diagnostics, Application > Occupational Safety and Health, Application > Research Materials
Occupational Health: Wearable Kneel-Sit Support Device for Manual Labor and Heavy Industry Applications
This CDC-developed technology describes a novel ergonomic device that supports a portion of the worker's weight while kneeling, relieving the knee pressure and pain common to many manual labor occupations. Unfortunately, many of the devices that have been used in the past to relieve pressure on the knees are bulky, heavy, and of questionable durability. This...
Published: 7/25/2024   |   Inventor(s): Ova Johnston, Stephen Hudock, Steven Wurzelbacher
Keywords(s): AB1XXX, AB3GXX, AB3XXX, AE2BXX, AE2XXX, AE4XXX, AEXXXX, AFXXXX, ARTHRITIS, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, DEVICE, Knee, Kneel-sit, LABOR, MINING, NIOSH, NIOSH-DART, OSHA, OSTEOARTHRITIS, SAFETY, SUPPORT, VAXXXX, VMXXXX, VPXXXX, Wearable, WEXXXX, WGXXXX, WMXXXX, WORK, WORKER, WORKER safety, WORKERS, XDXXXX, XIXXXX, YEXXXX, YFXXXX
Category(s): Collaboration Sought > Licensing, Application > Medical Devices, TherapeuticArea > Geriatrics, Application > Occupational Safety and Health, TherapeuticArea > Ophthalmology, TherapeuticArea > Dental, Application > Consumer Products, TherapeuticArea > Endocrinology, TherapeuticArea > Oncology, TherapeuticArea > Immunology, TherapeuticArea > Neurology, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Infectious Disease
Improved Acoustic Plethysmograph System for Noninvasive Measurement of Pulmonary Function
CDC researchers have developed a novel acoustic whole body plethysmograph (AWBP) that allows measurement of tidal volume in lab animals, independent of gas compression in the lung. This system provides particular advantages over the traditional whole body plethysmograph (WBP) when measuring model animals with increased gas compression due to increased...
Published: 7/25/2024   |   Inventor(s): David Frazer, Jeffrey Reynolds
Keywords(s): AA2XXX, AA5XXX, AAXXXX, AC1XXX, AC2XXX, AC3XXX, AC6XXX, Acoustic, ACXXXX, ADXXXX, AE1BXX, AE1XXX, AE3XXX, AE4XXX, AEXXXX, ANIMAL, Animal Model, ANIMAL welfare, ASTHMA, Breath, BREATHING, CDC Docket Import, CDC Docket Import CDC Prosecuting, DDXXXX, DEVICE, DEXXXX, DXXXXX, FUNCTION, IA3XXX, IA5XXX, ICXXXX, IDXXXX, LUNG, lung cancer, Lung Disease, LUNGS, Lung-Targeted, Measuring, NIOSH, NIOSH-HELD, Plethysmograph, Pulmonary, Pulmonary edema, PULMONARY FIBROSIS, research, RESEARCH TOOL, RESPIRABLE, Respiration, respiratory, Respiratory Diseases, respiratory INFECTION, Tool, VBXXXX, VJXXXX, VKXXXX, VLXXXX, VOXXXX, VPXXXX, WAXXXX, WBXXXX, WCXXXX, WGXXXX, WIXXXX, WMXXXX, XDXXXX, XHXXXX, XIXXXX, XJXXXX, YCXXXX, YEXXXX, YFXXXX
Category(s): Collaboration Sought > Licensing, Application > Software / Apps, Application > Medical Devices, Application > Diagnostics, TherapeuticArea > Pulmonology, TherapeuticArea > Immunology, Application > Research Materials, ResearchProducts > Research Equipment, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Ophthalmology, Application > Vaccines, Application > Therapeutics, Application > Occupational Safety and Health, TherapeuticArea > Infectious Disease, Application > Consumer Products, TherapeuticArea > Dental, TherapeuticArea > Endocrinology, ResearchProducts > Computational models/software, TherapeuticArea > Oncology
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