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Search Results - vaccine
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Peptide ligands for affinity capture of mRNA and methods of discovery thereof
RPI ID: 2022-060-301 Innovation Summary: This technology describes peptide ligands engineered for the affinity capture of nucleic acids, including DNA and RNA, in solution. These ligands are designed to bind selectively to nucleic acid targets, enabling efficient isolation and purification. The method includes synthesis and screening of peptide sequences...
Published: 3/10/2026
|
Inventor(s):
Pankaj Karande
,
Mengyang Hu
,
Georges Belfort
Keywords(s):
mRNA
,
Peptides
,
Purification
,
Vaccine
Category(s):
Biotechnology and the Life Sciences
Ligand design method for affinity capture of mRNA in solution and on a surface and ligands discovered thereof
RPI ID: 2022-061-601 Innovation Summary: This technology describes ligands and associated methods for affinity capture of mRNA molecules in solution. The ligands are designed to bind selectively to mRNA surfaces, enabling efficient isolation and purification. The system supports scalable mRNA processing for therapeutic and research applications. It...
Published: 3/10/2026
|
Inventor(s):
Todd Przybycien
,
Mirco Sorci
,
Thomas Neuman
,
Riddhi Banik
,
Georges Belfort
Keywords(s):
mRNA
,
Purification
,
Vaccine
Category(s):
Biotechnology and the Life Sciences
DESIGN OF UNIVERSAL H5 INFLUENZA VIRUS
VACCINE
CANDIDATES VIA ANTIGEN REORIENTATION
DESIGN OF UNIVERSAL H5 INFLUENZA VIRUS
VACCINE
CANDIDATES VIA ANTIGEN REORIENTATION Researchers at Stanford University have developed novel universal vaccine candidates for H5 influenza viruses. Influenza remains a serious threat to public health. H5 avian influenza strains are among the most concerning despite lack of documented human to human...
Published: 9/24/2024
|
Inventor(s):
Duo Xu
,
Peter Kim
Keywords(s):
Immunofocusing
,
Vaccine
Category(s):
Technology Classifications > Biology
Highly Immunogenic, Universal COVID-19
Vaccine
Description This technology is a novel, universal COVID-19
vaccine
platform designed to greatly enhance the immune response to a wide variety of strains of SARS-CoV-2, including original, Delta, and Omicron. In-vivo studies show remarkable animal survival rates with no weight loss for a number of different SARS-CoV-2 variants. As of April 2024,...
Published: 3/20/2025
|
Inventor(s):
Lanying Du
,
Juan Shi
,
Gang Wang
,
Fang Li Lee
Keywords(s):
Vaccine
Category(s):
Vaccine
Highly Effective T Cell-Exclusive COVID
Vaccine
Description This technology is a COVID-19
vaccine
that exclusively elicits T-cell responses without antibody responses. This design ensures sustained protection against various strains of SARS-CoV-2. Animal models challenged with both original and Omicron variants are protected against death and weight loss and show a significant reduction in viral...
Published: 7/18/2025
|
Inventor(s):
Lanying Du
,
Juan Shi
,
Ryan Compas
,
Liang Qiao
Keywords(s):
Vaccine
Category(s):
Vaccine
HIGH THROUGHPUT METHOD FOR SCREENING LIPID NANOPARTICLE EFFICACY AND CYTOTOXICITY
HIGH THROUGHPUT METHOD FOR SCREENING LIPID NANOPARTICLE EFFICACY AND CYTOTOXICITY Researchers at Berkeley have developed synthetic cell membranes that are optimized for screening the toxicity and efficacy of lipid nanoparticle formulations in vitro, in a high throughput format. Lipid nanoparticles (LNPs) represent a highly effective and efficient...
Published: 4/22/2024
|
Inventor(s):
Markita Landry
,
Alison Lui
Keywords(s):
Nanoparticle
,
SARS-CoV-2
,
Vaccine
Category(s):
Technology Classifications > Biology
DESIGN OF A UNIVERSAL INFLUENZA
VACCINE
CANDIDATES VIA ANTIGEN REORIENTATION
DESIGN OF A UNIVERSAL INFLUENZA
VACCINE
CANDIDATES VIA ANTIGEN REORIENTATION Researchers at Stanford have developed a novel universal influenza vaccine candidate. Vaccines are a major feat of biomedical innovation. Successful vaccines produce broad humoral immunity to a pathogen to prevent subsequent infection. In this vein, adjuvants are compounds...
Published: 12/5/2023
|
Inventor(s):
Duo Xu
,
Peter Kim
Keywords(s):
Adjuvant
,
Alum
,
Infectious Disease
,
Vaccine
Category(s):
Technology Classifications > Biology
IMMUNOGENIC EBOLAVIRUS FUSION PROTEINS AND RELATED METHODS
IMMUNOGENIC EBOLAVIRUS FUSION PROTEINS AND RELATED METHODS Researchers at Stanford have developed a novel
vaccine
strategy for ebolavirus using fusion proteins composed of the virus’ glycoprotein. Hemorrhagic fevers have become a major public health issue in Africa, the most notable of which being Ebola. Ebola has a notably high mortality...
Published: 10/6/2023
|
Inventor(s):
Peter Kim
,
Duo Xu
,
Abigail Powell
Keywords(s):
Ebola Virus
,
Infectious Disease
,
Vaccine
Category(s):
Technology Classifications > Biology
CHEMICALLY MODIFIED BACTERIAL PEPTIDOGLYCAN COMPOSITIONS AND USES THEREOF
CHEMICALLY MODIFIED BACTERIAL PEPTIDOGLYCAN COMPOSITIONS AND USES THEREOF Researchers at Stanford have developed a new microparticle
vaccine
scaffold for the development of immunogenic subunit vaccines. Vaccines are one of the most important biomedical advances of the 20th century. Protein vaccines, often referred to as subunit vaccines, have proved...
Published: 8/17/2023
|
Inventor(s):
Peter Kim
,
Carolyn Bertozzi
,
Frances RodrÃguez-Rivera
Keywords(s):
Adjuvant
,
Bacteria
,
Peptidoglycan
,
Vaccine
Category(s):
Technology Classifications > Biology
High Efficacy
Vaccine
and Microbicide Combination For Use Against HIV
Abstract: Human immunodeficiency virus (HIV) remains a major global health challenge despite the advancement made in development of effective antiretrovirals (ARVs). ARVs are effective at limiting replication and spread of the virus, and progression to acquired immuno-deficiency syndrome (AIDS). However, ARVs often lead to emergence of drug-resistant...
Published: 4/22/2025
|
Inventor(s):
Genoveffa Franchini
,
Marjorie Robert-Guroff
,
Daniel Appella
,
Sabrina Helmold Hait
,
Mohammed Rahman
,
Massimiliano Bissa
,
Ettore Appella
,
Lisa Marie Jenkins
,
Isabela Silva De Castro
Keywords(s):
Acquired Immuno-Deficiency Syndrome
,
ADCC
,
AIDS
,
Antibody-dependent Cellular Cytotoxicity
,
Efferocytosis
,
Envelope Glycoprotein 120
,
Envelope Variable Region
,
Franchini
,
gp120
,
HIV
,
Human Immunodeficiency Virus
,
Microbicide
,
SAMT-247
,
V1
,
Vaccine
Category(s):
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
,
TherapeuticArea > Infectious Disease
,
TherapeuticArea > Immunology
,
Application >
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