Search Results - covid19

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Nasal spray using PPS and MPS for COVID-19 prevention and treatment

RPI ID: 2021-049-201 Innovation Summary: A nasal spray formulation combines pentosan polysulfate and mucopolysaccharide polysulfate to prevent and treat COVID-19. The compounds act as viral entry inhibitors by blocking spike protein binding to host cells. The spray is designed for prophylactic and therapeutic use, with potential for broad-spectrum...

Published: 3/10/2026 | Inventor(s): Fuming Zhang, Jawed Fareed, Walter Jeske, Robert Linhardt

Keywords(s): antiviral drug, COVID19, Heparin, mucopolysachharide polysulfate, Nasal spray, Pentosan polysulfate, prevention

Category(s): Biotechnology and the Life Sciences

Use of HCV NS3/4A Protease Inhibitors as Therapeutics for COVID-19

RPI ID: 2021-001-401 Innovation Summary: A therapeutic composition combines multiple protein inhibitors to target SARS-CoV-2 replication pathways. The method leverages synergistic interactions between inhibitors to enhance antiviral efficacy. It includes formulations for systemic and localized delivery, and supports adaptation to emerging variants....

Published: 3/10/2026 | Inventor(s): Khushboo Bafna, Robert Krug, Aldolfo Garcia-Sastre, Kris White, Gaetano Montelione

Keywords(s): COVID19, COVID-19 antivirals, Hepatitis C viral protease inhibitors, Repurposed Drugs

Category(s): Biotechnology and the Life Sciences

Smartphone Diagnostic for Rapid Respiratory Virus Detection

Application Diagnostic and automatic surveillance platform to identify RSV, Influenza A, and COVID-19 in real-time. Key Benefits Rapid smartphone-based detection of multiple respiratory viruses in nasal swab, breath condensate, and saliva. Requires few reagents and no expensive equipment. Limit of detection on par with PCR and rapid readout. Enables...

Published: 2/5/2026 | Inventor(s): Selma Piranej, Khalid Salaita

Keywords(s): COVID19, Molecular Diagnostics, Platform

Category(s): TechPub Algolia > Diagnostics

MVA and DNA Based SARS-CoV-2 Vaccines

Application Modified Vaccinia virus Ankara (MVA)- and deoxyribonucleic acid (DNA)-based vaccine for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Key Benefits Safety profile is known. Demonstrated antiviral activity against related Coronaviruses. Single dose of vaccination was shown to be effective against related Coronaviruses...

Published: 3/11/2026 | Inventor(s): Rama Rao Amara, Sailaja Gangadhara

Keywords(s): Biologics, COVID19, DNA and RNA Vaccines, Immunology and Inflammation Treatments, Microbiology and Infectious Disease Treatments

Category(s): TechPub Algolia > Vaccines

Using Hetero-multivalent DNA-functionalized Materials to Detect Genetic Mutations

Application Improving diagnostic accuracy using hetero-multivalent DNA-functionalized materials for disease targets containing one or more genetic mutations. Key Benefits Tunable oligos increase specificity and cooperative binding to the disease target of interest. Distinguishes between cis- and trans mutations. Identifies different strains of...

Published: 1/20/2026 | Inventor(s): Brendan Deal, Khalid Salaita, Rong Ma, James Kindt

Keywords(s): COVID19, Screening Assays

Category(s): TechPub Algolia > Micro and Nanotechnology, TechPub Algolia > Diagnostics

Mobile Phone Diagnostic for COVID-19

Application Diagnostic and automatic surveillance to identify COVID-19 via smartphone in real-time. Key Benefits Provides real-time, rapid results. Autonomous process. Device does not require RNA isolation or amplification for viral detection. Market Summary Coronavirus (COVID-19) is an infectious disease that causes severe acute respiratory...

Published: 1/20/2026 | Inventor(s): Khalid Salaita, Alisina Bazrafshan, Selma Piranej

Keywords(s): COVID19, Mobile Apps, Point-of-Care

Category(s): TechPub Algolia > Diagnostics

Improved Clinical Diagnostic Method for SARS-CoV-2 Infection

Application A more reliable and accurate method for diagnosing SARS-CoV-2 infection based on the biochemical interactions between the spike trimer and ACE-2 protein. Key Benefits A fast, affordable, and easy-to-use SARS-Cov-2 diagnostic test for use in clinical settings. Market Summary SARS-CoV-2 has evolved significantly since the onset of...

Published: 9/3/2025 | Inventor(s): John Roback, Andrew Neish, Narayanaiah Cheedarla, Hans Verkerke, Huixia Wu, William Osick, Kaleb Mclendon, Sindhu Potlapalli

Keywords(s): COVID19, Molecular Diagnostics

Category(s): TechPub Algolia > Research Tools, TechPub Algolia > Diagnostics

Extended Efficacy SARS-COV-2 Vaccine

Application A vaccine for SARS-COV-2 that can be used to protect against infection by future forms of Variant-of-Concern (VOC) or other SARS-like coronaviruses. Key Benefits An approach to developing a vaccine that would be effective against future mutations of SARS-COV-2. A vaccine that elicits an immune response to conserved portions...

Published: 1/20/2026 | Inventor(s): Chinglai Yang, Ling Ye, Samuel Stampfer, Rui Jin

Keywords(s): COVID19, Platform, Preventive Vaccines

Category(s): TechPub Algolia > Vaccines

SARS-CoV-2 Subgenomic Replicon (SARS2-Rn)

Application A series of SARS-CoV-2 sub-genomic replicons as artificial bacterial chromosomes for the screening of SARS-CoV-2 in studies such as drug discovery and inhibitors assay. Key Benefits Can be used at a lower biosafety level than non-artificial copies of SARS-CoV-2. Can be used for high throughput screening and characterization of SARS-CoV-2...

Published: 11/3/2025 | Inventor(s): Stefan Sarafianos, Shuiyun Lan

Keywords(s): COVID19, High-Throughput Screening

Category(s): TechPub Algolia > Drug Discovery

Yongshi: A Wild Boar Peptide with Anti-Viral Activity Targeting COVID-19

Application An antiviral cathelicidin peptide from wild boar that exhibits antiviral properties against SARS-CoV-2. Key Benefits Pan-coronavirus inhibitor that may be effective for all future variants. Functions as an inhibitor of ongoing infection. Early data suggests it is safe to use in human tissue. Market Summary Coronavirus disease...

Published: 1/20/2026 | Inventor(s): Joshy Jacob, Mehul Suthar, Troy Von Beck, Nikita Mullick, Abigail Vanderheiden, Jeffrey Skolnick

Keywords(s): COVID19, Preventive Vaccines

Category(s): TechPub Algolia > Therapeutics, TechPub Algolia > Vaccines

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