Search Results - covid19

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Smartphone Diagnostic for Rapid Respiratory Virus Detection
Application Diagnostic and automatic surveillance platform to identify RSV, Influenza A, and COVID-19 in real-time. Key Benefits Rapid smartphone-based detection of multiple respiratory viruses in nasal swab, breath condensate, and saliva. Requires few reagents and no expensive equipment. Limit of detection on par with PCR and rapid readout. Enables...
Published: 10/17/2024   |   Inventor(s): Selma Piranej, Khalid Salaita
Keywords(s): COVID19, Microbiology/Infectious Diseases, Platform, Respiratory
Category(s): TechPub Algolia > Diagnostics
MVA and DNA Based SARS-CoV-2 Vaccines
Application Modified Vaccinia virus Ankara (MVA)- and deoxyribonucleic acid (DNA)-based vaccine for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Key Benefits Safety profile is known. Demonstrated antiviral activity against related Coronaviruses. Single dose of vaccination was shown to be effective against related Coronaviruses...
Published: 10/28/2024   |   Inventor(s): Rama Rao Amara, Sailaja Gangadhara
Keywords(s): Biologic, COVID19, Immunology/Inflammation, Microbiology/Infectious Diseases
Category(s): TechPub Algolia > Vaccines
Using Hetero-multivalent DNA-functionalized Materials to Detect Genetic Mutations
Application Improving diagnostic accuracy using hetero-multivalent DNA-functionalized materials for disease targets containing one or more genetic mutations. Key Benefits Tunable oligos increase specificity and cooperative binding to the disease target of interest. Distinguishes between cis- and trans mutations. Identifies different strains of...
Published: 10/28/2024   |   Inventor(s): Brendan Deal, Khalid Salaita, Rong Ma, James Kindt
Keywords(s): COVID19, Genetic Disorders
Category(s): TechPub Algolia > Micro and Nanotechnology, TechPub Algolia > Diagnostics
Mobile Phone Diagnostic for COVID-19
Application Diagnostic and automatic surveillance to identify COVID-19 via smartphone in real-time. Key Benefits Provides real-time, rapid results. Autonomous process. Device does not require RNA isolation or amplification for viral detection. Market Summary Coronavirus (COVID-19) is an infectious disease that causes severe acute respiratory...
Published: 10/17/2024   |   Inventor(s): Khalid Salaita, Alisina Bazrafshan, Selma Piranej
Keywords(s): COVID19
Category(s): TechPub Algolia > Diagnostics
Improved Clinical Diagnostic Method for SARS-CoV-2 Infection
Application A more reliable and accurate method for diagnosing SARS-CoV-2 infection based on the biochemical interactions between the spike trimer and ACE-2 protein. Key Benefits A fast, affordable, and easy-to-use SARS-Cov-2 diagnostic test for use in clinical settings. Market Summary SARS-CoV-2 has evolved significantly since the onset of...
Published: 9/26/2024   |   Inventor(s): John Roback, Andrew Neish, Narayanaiah Cheedarla, Hans Verkerke, Huixia Wu, William Osick, Kaleb Mclendon, Sindhu Potlapalli
Keywords(s): COVID19, Microbiology/Infectious Diseases
Category(s): TechPub Algolia > Research Tools, TechPub Algolia > Diagnostics
SARS-CoV-2 Neutralizing Human Monoclonal Antibodies
­ Application Monoclonal antibodies to SARS-CoV2 for use in COVID-19 diagnostics and therapeutics. Key Benefits Demonstrably neutralizing, important for therapeutic mAbs. Most bind both RBG and stalk portion of spike protein, useful in case SARS-CoV2 strains develop variation in RBD. Market Summary Coronavirus (COVID-19) is an infectious...
Published: 10/17/2024   |   Inventor(s): Jens Wrammert, Carl Davis, Mehul Suthar, Robert Kauffman
Keywords(s): Antibody, COVID19, Microbiology/Infectious Diseases
Category(s): TechPub Algolia > Diagnostics, TechPub Algolia > Therapeutics
Extended Efficacy SARS-COV-2 Vaccine
­ Application A vaccine for SARS-COV-2 that can be used to protect against infection by future forms of Variant-of-Concern (VOC) or other SARS-like coronaviruses. Key Benefits An approach to developing a vaccine that would be effective against future mutations of SARS-COV-2. A vaccine that elicits an immune response to conserved portions...
Published: 10/28/2024   |   Inventor(s): Chinglai Yang, Ling Ye, Samuel Stampfer, Rui Jin
Keywords(s): COVID19
Category(s): TechPub Algolia > Vaccines
SARS-CoV-2 Subgenomic Replicon (SARS2-Rn)
Application A series of SARS-CoV-2 sub-genomic replicons as artificial bacterial chromosomes for the screening of SARS-CoV-2 in studies such as drug discovery and inhibitors assay. Key Benefits Can be used at a lower biosafety level than non-artificial copies of SARS-CoV-2. Can be used for high throughput screening and characterization of SARS-CoV-2...
Published: 10/17/2024   |   Inventor(s): Stefan Sarafianos, Shuiyun Lan
Keywords(s): COVID19
Category(s): TechPub Algolia > Drug Discovery
Yongshi: A Wild Boar Peptide with Anti-Viral Activity Targeting COVID-19
­ Application An antiviral cathelicidin peptide from wild boar that exhibits antiviral properties against SARS-CoV-2. Key Benefits Pan-coronavirus inhibitor that may be effective for all future variants. Functions as an inhibitor of ongoing infection. Early data suggests it is safe to use in human tissue. Market Summary Coronavirus disease...
Published: 9/26/2024   |   Inventor(s): Joshy Jacob, Mehul Suthar, Troy Von Beck, Nikita Mullick, Abigail Vanderheiden, Jeffrey Skolnick
Keywords(s): COVID19
Category(s): TechPub Algolia > Therapeutics
Combination of Tetrahydrobiopterin and Arginine/ ± Arginase Inhibitors for the Treatment of COVID-19
­ Application A novel drug combination to address acute arginine/BH4 dysregulation that develops with COVID-19 and MIS-C infection. Key Benefits Potential to improve outcomes of those infected with COVID-19 with few side effects. Repurposing opportunity with the combination of two approved drugs (tetrahydrobiopterin and arginine). Addresses...
Published: 7/30/2024   |   Inventor(s): Claudia Morris, Lou Ann Brown
Keywords(s): COVID19, Microbiology/Infectious Diseases
Category(s): TechPub Algolia > Therapeutics
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