Search Results - life+science+research+tools+%3e+microscopy+and+imaging

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High-Throughput Cell Screening With Interferometric Cytometry (Case No. 2007-720)
Summary The combined technology platform encompasses optical cytometry via interferometric membrane probing and cell mechanical / membrane property characterization, using reflective microparticles and interferometric imaging to measure deformation and viscoelastic response of live cells. The approach links physical membrane dynamics to cellular state,...
Published: 9/25/2025   |   Inventor(s): Michael Teitell, James Gimzewski, Jason Reed
Keywords(s):  
Category(s): Life Science Research Tools, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Microfluidics And Mems
Pulsed Laser Triggered High Speed Microfluidic Switch and Applications in Flourescent Activated Cell Sorting (Case No. 2009-063)
Summary UCLA researchers have developed a pulsed-laser triggered microfluidic switching mechanism capable of sub-100 µs switching (e.g. ~70 µs), enabling ultrafast cell/particle sorting in a microfluidic fluorescence-activated cell sorting (µFACS) platform using cavitation bubbles rather than mechanical valves. Background Flow cytometry...
Published: 9/25/2025   |   Inventor(s): Pei-Yu Chiou, Ting Hsiang Wu
Keywords(s):  
Category(s): Optics & Photonics, Optics & Photonics > Lasers, Life Science Research Tools, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Microfluidics And Mems, Life Science Research Tools > Research Methods
Methods for Determining Drug-Target Structures by Combining Mass Spectrometry and Electron Diffraction (UCLA Case No. 2025-229)
UCLA researchers in the Department of Chemistry and Biochemistry have developed a novel approach to study protein-ligand interactions by integrating native mass spectrometry with electron diffraction. BACKGROUND: The accurate characterization of small molecule-protein interactions is crucial for biomedical research. High-throughput structural methods,...
Published: 10/29/2025   |   Inventor(s): Jose Rodriguez
Keywords(s):  
Category(s): Life Science Research Tools, Life Science Research Tools > Mass Spectrometry
High-Throughput, Multi-Well Spatiotemporal Illumination Microscope (UCLA Case No. 2024-100)
UCLA researchers from the Department in Neurology have developed a spatiotemporal illumination microscope system. The system includes a multi-well plate configured to receive live cells and a DMD (Digital Micromirror Device) configured to deliver targeted illumination to selectively illuminate a plurality of the wells. The system further includes a...
Published: 9/15/2025   |   Inventor(s): Daniel Aharoni
Keywords(s):  
Category(s): Life Science Research Tools > Microscopy And Imaging
Cohesive CLEM, TEM, FEBSEM System for MicroED and Cryo-EM Applications (Case No. 2025-010)
Summary UCLA researchers have developed a cohesive electron microscope system that uniquely integrates transmission electron microscopy (TEM), fluorescence microscopy, and focused ion beam scanning electron microscopy (FIB-SEM) into a single automated column. The platform supports both cryogenic and room-temperature workflows, enabling fully automated...
Published: 10/24/2025   |   Inventor(s): Tamir Gonen, Michael Martynowycz
Keywords(s):  
Category(s): Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Research Methods, Medical Devices, Medical Devices > Medical Imaging, Platforms
On Grid Sample Growth Device for Imaging Applications (Case No. 2023-048)
Summary UCLA researchers have developed a suspended drop crystallization device and associated methods that allow a sample to be applied directly onto a support-free electron microscopy grid and then incubated in a chamber (“incubation pod”) that permits vapor diffusion from both sides. The device has viewing windows for monitoring crystal...
Published: 9/11/2025   |   Inventor(s): Tamir Gonen, Cody Gillman
Keywords(s):  
Category(s): Medical Devices, Medical Devices > Medical Imaging, Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging
Refractive Index-Corrected Light-Sheet Microscopy (Case No. 2025-176)
Summary: UCLA researchers from the Department of Medicine have developed a novel light-sheet fluorescence microscopy system that enables adaptive imaging across a range of refractive indices for enhanced biomedical imaging. Background: Light-sheet fluorescence microscopy (LSFM) has revolutionized biomedical imaging by allowing rapid and high-resolution...
Published: 10/17/2025   |   Inventor(s): Tzung Hsiai, Enbo Zhu
Keywords(s): bioimaging, cell imaging, Fluorescence, fluorescence lifetime, Fluorescence Microscope, fluorescence microscopy, Fluorescence-Lifetime Imaging Microscopy Leading Lights, Fluorescent Labelling, Hyperspectral Imaging, immunofluorescence, Microscope, Microscopy, Microscopy And Imaging, Near-Field Scanning Optical Microscope
Category(s): Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > Fluorescence, Optics & Photonics, Optics & Photonics > Microscopy, Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging
Multi-Particle System for Capture and Detection of Cellular and Molecular Analytes (Case No. 2025-267)
Summary: UCLA researchers in the Department of Bioengineering have developed a novel multi-particle system that selectively confines cells and molecular reactions within cavities formed by interacting particles. Background: Screening and selecting cells with specific, beneficial traits has become a vital process in using cell-derived products...
Published: 10/20/2025   |   Inventor(s): Dino Di Carlo, Alyssa Arnheim, Michael Mellody, Yuta Nakagawa, Lily Shang
Keywords(s): Assay, B Cell, barcode, Bioassay, biological assays, Biomarker, biomarkers, Biomaterial, capping particles, CAR-T cell platform, CAR-T cell therapy, cavities, cavity-containing particles, Cell and tissue culture, cell encapsulation, cell engineering, cell imaging, cell mapping, cell sorting, cell type identification, cell-based therapy, centrifugation, confinement, Diagnostic Platform Technologies (E.G. Microfluidics), Digital Microfluidics, Drug, Drug Delivery, Drug Discovery, drug screening, high throughput, high throughput assays, high throughput testing, high-throughput analysis, High-Throughput Screening, Immunoassay, Immunoassay Sense (Molecular Biology), Microfluidics, Microfluidics And Mem's, Microfluidics Nanosphere, microparticles, moieties, Nanoparticle, single cell analysis, single cell analysis and testing, Single cell data, single-cell resolution, single-cell trapping
Category(s): Life Science Research Tools, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Lab Equipment, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Microfluidics And Mems, Medical Devices, Platforms
Methods and Systems for Low-Cost Medical Image Annotation Using Non-experts (Case No. 2025-108)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed an AI-based interface designed to enable individuals without specialized training to identify arthritis in medical imaging. Background: The use of artificial intelligence (AI) for medical imaging analysis holds great promise for the future of healthcare....
Published: 10/24/2025   |   Inventor(s): Xiang Chen, Youngseung Jeon, Christopher Hwang
Keywords(s): 3D tissue imaging, AI-guided diagnostics, AI-guided medical imaging, AI-guided medical intervention, arthritis, Artifical Intelligence (Machine Learning, Data Mining), Artificial Intelligence, artificial intelligence algorithms, artificial intelligence augmentation, artificial intelligence/machine learning models, Artificial Neural Network, bioimaging, Computer-Aided Diagnosis, computer-aided radiology, Diagnostic Markers & Platforms, Diagnostic Test, diagnostics, generative artificial intelligence, Image Analysis, Image Resolution, Imaging, infrared thermal imaging, Machine Learning, machine learning modeling, machine perception, Magnetic Resonance Imaging Medical Physics, Magnetic Resonance Imaging Pathology, Medical artificial intelligence (AI), Medical diagnostics, Medical Imaging, Microscopy And Imaging, non-invasive imaging, osteoarthritis, radial MRI, radiologic imaging, Radiology, Radiology / Radiomitigation, radiosurgery
Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Digital Health, Software & Algorithms > Image Processing, Life Science Research Tools, Life Science Research Tools > Lab Equipment, Life Science Research Tools > Microscopy And Imaging, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Monitoring And Recording Systems, Therapeutics, Therapeutics > Musculoskeletal Disease, Therapeutics > Radiology
Blurryscope (Case No. 2025-070)
Summary: Researchers in the UCLA Department of Electrical and Computer Engineering have developed a cost-effective digital scanning microscope to improve pathological screening. Background: High quality pathological imaging systems are essential to carefully assess tissue sectioning samples and produce accurate diagnoses for patients. Digitization...
Published: 6/11/2025   |   Inventor(s): Aydogan Ozcan, Michael Fanous, Christopher Seybold
Keywords(s):  
Category(s): Electrical, Electrical > Imaging, Electrical > Instrumentation, Life Science Research Tools, Life Science Research Tools > Lab Equipment, Life Science Research Tools > Microscopy And Imaging, Optics & Photonics, Optics & Photonics > Microscopy, Software & Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Image Processing
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