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Label-Free Optical Mapping for Large-Area Biomechanical Dynamics of Multicellular Systems (Case No. 2023-290)
Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel label-free optical mapping method for profiling real-time biomechanical dynamics over larger areas with high spatiotemporal resolution. Background: Mapping biomechanical dynamics often involves the use of various advanced technologies to measure...
Published: 6/27/2024
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Inventor(s):
Pei Yu Chiou
,
Yen-Ju Lin
Keywords(s):
bioimaging
,
Biomechanics
,
cell imaging
,
Confocal Microscopy
,
dye
,
Fluorescence Microscope
,
labeling
,
Microscopy
,
Microscopy And Imaging
,
resolution
,
traction force microscopy
Category(s):
Life Science Research Tools
,
Life Science Research Tools > Microscopy And Imaging
,
Life Science Research Tools > Cell Counting And Imaging
,
Medical Devices
,
Medical Devices > Medical Imaging
,
Platforms
,
Platforms > Diagnostic Platform Technologies
A New Class of Stable Heptamethine Cyanine Fluorophores and Biomedical Applications Thereof
Abstract: Heptamethine cyanines are among the most widely used near-IR fluorophores. The near-IR range (between about 650 nm and 900 nm) is very useful for imaging applications due to the absence of background autofluorescence. Despite extensive use, many of these fluorophores suffer from chemical instability. Specifically, most of the current and commonly...
Published: 4/8/2024
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Inventor(s):
Martin Schnermann
,
Roger Nani
,
James Shaum
Keywords(s):
Antibody labeling
,
DYE
,
Fluorescence-activated cell sorting (FACS)
,
Fluorophore
,
Heptamethine Cyanines
,
IMAGING
,
Imaging Microscopy
,
Imaging reagent
,
MICROSCOPY
,
near-IR fluorophores
,
Optical-Guided Surgery
Category(s):
TherapeuticArea > Oncology
,
Collaboration Sought > Licensing
,
Application > Research Materials
,
Collaboration Sought > Collaboration