Search Results - dna+nanotechnology

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DNA Gridiron
Self-assembling nucleic acid molecules have been utilized extensively for constructing unique nanoscale structures, and designing increasingly complex structures is a top nanotechnology challenge. Current methods to create NDA nanostructures are restricted to discrete domains of parallel lines as a result of the double crossover based unit motif, which...
Published: 4/14/2023   |   Inventor(s): Dongran Han, Hao Yan
Keywords(s): DNA nanotechnology
Category(s): Advanced Materials/Nanotechnology, Life Science (All LS Techs), Biomaterials, Chemical/Biological Sensors, Genomic Assays/Reagents/Tools
Compositions for Treatment of HER2 Positive Cancers
Many early stage cancers have a high rate of survival if promptly diagnosed and treated. Survival rates for stage 1-3 breast cancer can be as high as 95% at the 5 year mark. Unfortunately, late stage cancers have a much lower survival rate; stage 4 breast cancer only has about a 20% survival rate at the 5 year mark. Metastatic cancers pose a particularly...
Published: 2/23/2023   |   Inventor(s): Shengxi Chen, Yanmin Zhang, Sidney Hecht
Keywords(s): Cancer, Chemicals, DNA nanotechnology, Drug Delivery, Peptides
Category(s): Cancer Therapeutics, Life Science (All LS Techs), Pharmaceuticals, Advanced Materials/Nanotechnology
Microreactor Array Instrument/Platform
High throughput parallel assays are needed to effectively identify and study biomolecules and their activity. Typically it takes a large number of repeated assays to get statistically significant data for studying biomolecules. However, fewer assays would be needed to get statistically meaningful results if the data were of higher quality. Because of...
Published: 2/23/2023   |   Inventor(s): Peter Wiktor
Keywords(s): Array Techs - Micro, Nano, Gen,Proteomic, Bioassay, Bio-Technology, Detection, Diagnostics, Diffusion, DNA nanotechnology, Drug Discovery, Drug Screening, Drug Target Identification, ELISA, Genomics, Proteomics, Health Monitoring, High Throughput Sensors, Immunology, In situ, In Vitro, Instrumentation, Liquid Handling and Dispensing, MicroArray, Microbiology, Micro-Fluidics, Microreactor, Molecular Diagnostics, Nucleic Acid, Personalized medicine, Pharmaceutical, Polymerase Chain Reaction (PCR), Protein, Protein Assays
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Genomic Assays/Reagents/Tools, Proteomic Assays/Reagents/Tools
Probes and Methods for Measuring Tandem Repeats
Telomeres, tandem repeats at the ends of chromatids, are a particular point of interest in the science of aging and cancer. Telomeric DNA is lost during cellular replication, resulting in shortened chromatid length and cessation of cell division. Many age-related diseases are linked to shortened telomeres. Conversely, many cancer cells demonstrate elongated...
Published: 2/23/2023   |   Inventor(s): Fusheng Xiong, Wayne Frasch
Keywords(s): Bioassay, biomarker, Cancer, Diagnostics, DNA nanotechnology, Early Detection, Molecular Diagnostics, Personalized medicine, PS-Bioengineering, Medical, Sensors, Singe molecule analysis, Telomerase
Category(s): Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Genomic Assays/Reagents/Tools
Single Molecule Imaging Apparatus and Method for Noise and Interference Reduction
Interest in visualizing and analyzing individual biomolecules has increased significantly in the past twenty years or so, especially for DNA. Single molecule DNA imaging is critical for studying the biophysical and biochemical properties of DNA and for developing new applications. Typically DNA is imaged using fluorescence which has limited contrast...
Published: 2/23/2023   |   Inventor(s): Nongjian (nj) Tao
Keywords(s): DNA nanotechnology, Label-Free Imaging, Surface Plasmon Resonance Microscope
Category(s): Bioanalytical Assays, Chemistries & Devices, Genomic Assays/Reagents/Tools, Imaging, Life Science (All LS Techs)