Search Results - in+situ

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Single Cell In-Situ Extraction with Intact 3D Morphology from Formalin Fixed Paraffin Embedded (FFPE) Tissues
FFPE is a well-established and widely used method for preservation and histological analysis of tissue samples. DNA/RNA/and Proteins can be extracted from FFPE samples, but generally lack single cell resolution and completely lack 3D spatial resolution. Enabling 3D resolution allows the correlation of morphology to information like gene expression,...
Published: 4/25/2023   |   Inventor(s): David Richardson, Thai Tran, Dmitry Derkach, Colleen Ziegler
Keywords(s): Bioanalysis, Biological Cell Manipulation, Bio-Technology, Cancer, Device, Diagnostics, Gene Expression, Genomics, Proteomics, In situ, Molecular Diagnostics, Single-cell analysis
Category(s): Bioanalytical Assays, Chemistries & Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools
Microreactor Array Instrument/Platform
High throughput parallel assays are needed to effectively identify and study biomolecules and their activity. Typically it takes a large number of repeated assays to get statistically significant data for studying biomolecules. However, fewer assays would be needed to get statistically meaningful results if the data were of higher quality. Because of...
Published: 2/23/2023   |   Inventor(s): Peter Wiktor
Keywords(s): Array Techs - Micro, Nano, Gen,Proteomic, Bioassay, Bio-Technology, Detection, Diagnostics, Diffusion, DNA nanotechnology, Drug Discovery, Drug Screening, Drug Target Identification, ELISA, Genomics, Proteomics, Health Monitoring, High Throughput Sensors, Immunology, In situ, In Vitro, Instrumentation, Liquid Handling and Dispensing, MicroArray, Microbiology, Micro-Fluidics, Microreactor, Molecular Diagnostics, Nucleic Acid, Personalized medicine, Pharmaceutical, Polymerase Chain Reaction (PCR), Protein, Protein Assays
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Genomic Assays/Reagents/Tools, Proteomic Assays/Reagents/Tools
Versatile Embedded 3D Bioprinting to Create Thick Biomedical Tissue Structures
Creates Complex Thick Tissues Using a Cellular Hydrogel Composite MatrixThis biocompatible matrix bath enables rapid 3D printing of thick tissue analogues with custom features. Tissue engineering is a rapidly growing field that requires advanced fabrication techniques to create permeable thick constructs with specific channels, cavities, and cell compositions...
Published: 6/27/2021   |   Inventor(s): Yong Huang, Ashley Compaan, Wenxuan Chai, Kaidong Song
Keywords(s): bioprinting, composite materials, Embedded printing, Hydrogel, in situ, Microgel, perfusion, thick tissue
Category(s): Technology Classifications > Engineering > Materials
Improved Nanoparticle Production that Uses In-Situ Magnetic Processing
Overcomes Typical Nanoparticle Production Drawbacks by Synthesizing Particles with Acoustic Cavitation Produced in a Magnetic FieldThis approach to nanoparticle production uses a magnetic processing technique that utilizes cavitation and in-situ particle synthesis, producing metal alloy nanoparticles useful for industrial applications. In recent years,...
Published: 6/27/2021   |   Inventor(s): Michele Manuel, Hunter Henderson, Gerard Ludtka, Orlando Rios
Keywords(s): Carbon, cavitation, composite materials, in situ, magnetic processing, particle synthesis, Steel
Category(s): Technology Classifications > Engineering > Materials