Search Results - prathamesh+chopade

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SiMPLE: A Low-Cost, Scalable Method for High-Density DNA Origami Nanoarray Fabrication
Single-molecule techniques make it possible to digitally count even extremely rare biomarker molecules, providing greatly improved sensitivity for early disease detection. However, in standard setups, there is a necessary balance: if the concentration is too high, molecules overlap and become unreadable; if too low, there are not enough events for robust...
Published: 9/2/2025   |   Inventor(s): Prathamesh Chopade, Rizal Hariadi, Deeksha Satyabola, Aaron Sakai
Keywords(s):  
Category(s): Biological Nanotechnology, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools, Nucleic Acid/Peptide/Protein Therapies
High-Throughput DNA Origami Nanoarrays
Traditional bulk diagnostic assays suffer from signal dilution and averaging, making it difficult to detect rare biomarkers and subtle molecular variations critical for early disease diagnosis. Microarrays address this limitation by enabling high-throughput, multiplexed analysis with improved specificity and sensitivity. Their structured array format...
Published: 3/27/2025   |   Inventor(s): Prathamesh Chopade, Rizal Hariadi
Keywords(s): DNA nanotechnology, Lithography, MicroArray, Nanofabrication, Nucleic Acid, Single Molecule
Category(s): Advanced Materials/Nanotechnology, Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Biological Nanotechnology, Diagnostic Assays/Devices, Life Science (All LS Techs)