Search Results - rizal+hariadi

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Nucleic Acid-Triggered Gated Pore Formation for Sensing and Signal Amplification

Cells have developed various means for transporting molecules across membranes as well as cellular compartments separated by membranes. Channels and pores can be formed with different protein assemblies to enable the regulated passage of molecules in and out of cells, which has led to them being exploited as molecular sensors for characterizing biomolecules...

Published: 6/23/2025 | Inventor(s): Rizal Hariadi, Ranjan Sasmal

Keywords(s):

Category(s): Biological Nanotechnology, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices

High-Throughput DNA Origami Nanoarrays

Traditional bulk diagnostic assays suffer from signal dilution and averaging, making it difficult to detect rare biomarkers and subtle molecular variations critical for early disease diagnosis. Microarrays address this limitation by enabling high-throughput, multiplexed analysis with improved specificity and sensitivity. Their structured array format...

Published: 3/27/2025 | Inventor(s): Prathamesh Chopade, Rizal Hariadi

Keywords(s): DNA nanotechnology, Lithography, MicroArray, Nanofabrication, Nucleic Acid, Single Molecule

Category(s): Advanced Materials/Nanotechnology, Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Biological Nanotechnology, Diagnostic Assays/Devices, Life Science (All LS Techs)

Viral Attachment Blocking Chimera for Antiviral Therapeutics

Of the emerging pathogens, the most concerning seem to be pathogenic viruses. Antiviral therapeutics are integral in instances where vaccines are not effective (e.g. HIV or Herpes infections). Despite the recent SARS-CoV2 pandemic and other viral outbreaks, antivirals have been clinically approved to treat only 10 out of the greater than 200 known pathogenic...

Published: 2/13/2025 | Inventor(s): Rizal Hariadi, Carter Swanson, Swechchha Pradhan

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Life Science (All LS Techs), Pharmaceuticals, Non-Cancer Therapeutics