Search Results - biological+nanotechnology

9 Results Sort By:
Nanomaterial-Driven Healing in Healthy and Diabetic Wounds
Invention Description Chronic and slow-healing wounds, particularly in diabetic and obese patients, pose a significant global, medical, and economic burden due to poor healing outcomes and limited effective treatments. Post-operative complications such as intestinal adhesions further complicate recovery and emphasize the need for targeted wound therapies. ...
Published: 1/26/2026   |   Inventor(s): Kaushal Rege, Sudhakar Godeshala, Jordan Yaron
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Biological Nanotechnology, Biomaterials, Life Science (All LS Techs), Medical Devices
ASC-Targeted Nanoparticles for Browning White Adipose Tissue and Combatting Obesity and Metabolic Diseases
Invention Description Obesity and related metabolic diseases are increasing in prevalence in the US and worldwide. They are difficult to treat with traditional therapies such as lifestyle intervention, pharmacotherapy, and various surgical procedures because of low compliance, low efficacy, high side effects and cost. One promising new approach focuses...
Published: 1/12/2026   |   Inventor(s): Shu Wang, Aysegul Kartal Acet, Fang Zhou
Keywords(s):  
Category(s): Biological Nanotechnology, Non-Cancer Therapeutics, Nucleic Acid/Peptide/Protein Therapies, Pharmaceuticals
DNA Nanotechnology Platform for 3D Nanoscale Manufacturing
Invention Description One of the main challenges in nanoscale manufacturing is achieving precise three-dimensional (3D) positioning and organization of materials. DNA nanotechnology, such as DNA origami, offers a solution to this problem by leveraging the predictable base-pairing properties of DNA to design and construct nanoscale structures with molecular...
Published: 1/5/2026   |   Inventor(s): Petr Sulc, Hao Liu, Thong Diep, Matthew Sample, Michael Matthies, Joshua Evans
Keywords(s):  
Category(s): Life Science (All LS Techs), Nucleic Acid/Peptide/Protein Therapies, Vectors/Constructs/Plasmids, Biological Nanotechnology
SiMPLE: A Low-Cost, Scalable Method for High-Density DNA Origami Nanoarray Fabrication
Single-molecule techniques make it possible to digitally count even extremely rare biomarker molecules, providing greatly improved sensitivity for early disease detection. However, in standard setups, there is a necessary balance: if the concentration is too high, molecules overlap and become unreadable; if too low, there are not enough events for robust...
Published: 9/2/2025   |   Inventor(s): Prathamesh Chopade, Rizal Hariadi, Deeksha Satyabola, Aaron Sakai
Keywords(s):  
Category(s): Biological Nanotechnology, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools, Nucleic Acid/Peptide/Protein Therapies
Brain-Targeted Nanoparticles for Delivering Agents to the Brain
The blood brain barrier (BBB) is a highly selective semipermeable complex, and only about 2% of small molecules in the blood can penetrate it. Because of this, drug delivery to the brain is fairly ineffective. Research into receptors expressed on the BBB is promising, however, many receptors (glucose transporter 1, transferrin receptor, LDL-receptor...
Published: 8/27/2025   |   Inventor(s): Shu Wang, Zhaoyang Fan
Keywords(s):  
Category(s): Biological Nanotechnology, Diagnostic Assays/Devices, Imaging, Life Science (All LS Techs), Pharmaceuticals, Medical Imaging, Non-Cancer Therapeutics
Nucleic Acid-Triggered Gated Pore Formation for Sensing and Signal Amplification
Cells have developed various means for transporting molecules across membranes as well as cellular compartments separated by membranes. Channels and pores can be formed with different protein assemblies to enable the regulated passage of molecules in and out of cells, which has led to them being exploited as molecular sensors for characterizing biomolecules...
Published: 6/23/2025   |   Inventor(s): Rizal Hariadi, Ranjan Sasmal
Keywords(s):  
Category(s): Biological Nanotechnology, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices
DNA/RNA Origami Assembly Mediated by Functional Peptides
DNA and RNA nanostructures, e.g., DNA Origami, have great potential in biological applications, including extracellular matrix scaffolds and delivery vehicles for drugs and gene therapies. While folding DNA origami under physiological conditions is plausible, significant challenges and limitations remain. For example, isothermal annealing of DNA origami...
Published: 4/2/2025   |   Inventor(s): Di Liu, Bing Xu, Zhishang Li, Jiaqi Guo
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Biological Nanotechnology, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Manufacturing/Construction/Mechanical, Nucleic Acid/Peptide/Protein Therapies
High-Throughput DNA Origami Nanoarrays
Traditional bulk diagnostic assays suffer from signal dilution and averaging, making it difficult to detect rare biomarkers and subtle molecular variations critical for early disease diagnosis. Microarrays address this limitation by enabling high-throughput, multiplexed analysis with improved specificity and sensitivity. Their structured array format...
Published: 3/27/2025   |   Inventor(s): Prathamesh Chopade, Rizal Hariadi
Keywords(s): DNA nanotechnology, Lithography, MicroArray, Nanofabrication, Nucleic Acid, Single Molecule
Category(s): Advanced Materials/Nanotechnology, Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Biological Nanotechnology, Diagnostic Assays/Devices, Life Science (All LS Techs)
Metabolically-fit Immunotherapies Portfolio
M23-139L – Inducing or Rescuing Glycolysis in Cancer Cells. Compositions that selectively block glycolysis in cancer cells while simultaneously enable glycolysis in non-cancer cells, such as macrophages, T cells, NK cells, etc. Vaccine formulations have been developed and tested on mice with positive results. Please see the published PCT (WO2024151709A1)...
Published: 2/13/2025   |   Inventor(s):  
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Biomaterials, Biological Nanotechnology, Cancer, Cancer Therapeutics, Life Science (All LS Techs), Non-Cancer Therapeutics, Pharmaceuticals, Vaccines/Antimicrobials