Search Results - drug+target+identification

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Optimized Carbohydrates for Tumor Targeting
The bleomycins (BLMs) are well-known antineoplastic agents, clinically useful in the treatment of squamous cell carcinomas and malignant lymphomas. The carbohydrate moiety, particularly the disaccharide moiety, of BLM is also known to be highly tumor targeting. Researchers at the Biodesign Institute of Arizona State University have discovered disaccharides...
Published: 2/23/2023   |   Inventor(s): Sidney Hecht, Manikandadas Mathilakathu Madathil, Chandrabali Bhattacharya, Trevor Bozeman, Rakesh Paul, Zhiqiang Yu, Michael Rishel
Keywords(s): Diagnostics, Drug Target Identification, Imaging, Medical Devices and Imaging, Molecular Diagnostics
Category(s): Life Science (All LS Techs), Imaging, Medical Imaging, Pharmaceuticals
Microreactor Array Instrument/Platform
High throughput parallel assays are needed to effectively identify and study biomolecules and their activity. Typically it takes a large number of repeated assays to get statistically significant data for studying biomolecules. However, fewer assays would be needed to get statistically meaningful results if the data were of higher quality. Because of...
Published: 2/23/2023   |   Inventor(s): Peter Wiktor
Keywords(s): Array Techs - Micro, Nano, Gen,Proteomic, Bioassay, Bio-Technology, Detection, Diagnostics, Diffusion, DNA nanotechnology, Drug Discovery, Drug Screening, Drug Target Identification, ELISA, Genomics, Proteomics, Health Monitoring, High Throughput Sensors, Immunology, In situ, In Vitro, Instrumentation, Liquid Handling and Dispensing, MicroArray, Microbiology, Micro-Fluidics, Microreactor, Molecular Diagnostics, Nucleic Acid, Personalized medicine, Pharmaceutical, Polymerase Chain Reaction (PCR), Protein, Protein Assays
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Genomic Assays/Reagents/Tools, Proteomic Assays/Reagents/Tools
Label-free Detection of Small Molecules
The ability to measure molecular binding and interactions is important for understanding many biological processes. Particularly important is detecting the binding of small molecule drugs with their corresponding membrane protein receptors, which currently account for more than half of all drug targets. For effective measurements, purified membrane...
Published: 2/23/2023   |   Inventor(s): Nongjian (nj) Tao, Yan Guan
Keywords(s): Drug Discovery, Drug Screening, Drug Target Identification, Instrumentation, Microscopy, Sensors
Category(s): Bioanalytical Assays, Chemistries & Devices, Imaging, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools