Search Results - single+molecule

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High-Throughput DNA Origami Nanoarrays
Traditional bulk diagnostic assays suffer from signal dilution and averaging, making it difficult to detect rare biomarkers and subtle molecular variations critical for early disease diagnosis. Microarrays address this limitation by enabling high-throughput, multiplexed analysis with improved specificity and sensitivity. Their structured array format...
Published: 3/27/2025   |   Inventor(s): Prathamesh Chopade, Rizal Hariadi
Keywords(s): DNA nanotechnology, Lithography, MicroArray, Nanofabrication, Nucleic Acid, Single Molecule
Category(s): Advanced Materials/Nanotechnology, Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Biological Nanotechnology, Diagnostic Assays/Devices, Life Science (All LS Techs)
Molecular Semaphore Device for Single Molecule Detection
A major limitation of current methods to detect specific DNA sequences is the need to amplify the target DNA to detectable levels using PCR. The additional instrumentation and reagents required for PCR severely limit the portability of PCR based detection systems, greatly extend the time required for analysis, and potentially introduce significant...
Published: 2/23/2023   |   Inventor(s): Wayne Frasch, Lars Chapsky, Liyan He, Chia-Fu Chou, Frederic Zenhausern, Herb Goronkin
Keywords(s): Detection, Molecular, Nucleic Acid, Single Molecule
Category(s): Life Science (All LS Techs)