Search Results - biomaterials

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Invention Description Traditional hot-mix asphalt requires high temperatures for production and application, leading to significant energy consumption and environmental impact. In addition, maintaining durability and moisture resistance in harsh climates—especially with exposure to deicing salts—remains a persistent challenge for roadway...

Published: 4/23/2026 | Updated: 4/22/2026 | Inventor(s): Elham Fini, Albert Hung, Farideh Pahlavan, Mohammadjavad Kazemi

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Alternative Energy/Biofuels/Bioplastics/Algae, Biomaterials, Environmental, Manufacturing/Construction/Mechanical, Physical Science

Method and Compositions for Modulating PPAR activity in ISCs

Invention Description Diet profoundly impacts our nutritional landscape, public health, and disease susceptibility. In the gut, nutrients directly influence how intestinal stem cells (ISCs) function and maintain homeostasis. Yet, the connection between metabolic processes and transcriptional regulation are poorly defined. As a long-lived population,...

Published: 4/15/2026 | Updated: 4/15/2026 | Inventor(s): Thomas Hartley McDermott, Miyeko Mana

Keywords(s):

Category(s): Bioanalytical Assays, Chemistries & Devices, Biomaterials, Life Science (All LS Techs)

Green Synthesis of Biodegradable Cross-linked Polymeric Materials

Invention Description Because of their insulating and porous physical properties, polyurethanes are excellent materials for use in cushions and mattresses, insulation, packaging, acoustic absorbers and more. However, polyurethane synthesis requires catalysts, isocyanates and other agents which can be toxic and release concerning VOCs. In addition,...

Published: 2/26/2026 | Updated: 2/19/2026 | Inventor(s): Hannah Knipmeyer, Ryan Trovitch

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Biomaterials, Manufacturing/Construction/Mechanical, Medical Devices, Physical Science, Environmental

Nanomaterial-Driven Healing in Healthy and Diabetic Wounds

Invention Description Chronic and slow-healing wounds, particularly in diabetic and obese patients, pose a significant global, medical, and economic burden due to poor healing outcomes and limited effective treatments. Post-operative complications such as intestinal adhesions further complicate recovery and emphasize the need for targeted wound therapies. ...

Published: 2/26/2026 | Updated: 1/26/2026 | Inventor(s): Kaushal Rege, Sudhakar Godeshala, Jordan Yaron

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Biological Nanotechnology, Biomaterials, Life Science (All LS Techs), Medical Devices

Drop Tower System for Cavitation Quantification in Soft Biomaterials

Background Understanding the mechanical properties of biologically relevant soft materials is increasingly important for developing a comprehensive knowledge of the underlying injury mechanism and emerging biomedical applications such as tissue regeneration, and shockwave lithotripsy. Soft materials, which are composed of a variety of substances such...

Published: 2/26/2026 | Updated: 7/14/2025 | Inventor(s): Chunghwan Kim, Maxwell Kulak, Wonmo Kang

Keywords(s):

Category(s): Physical Science, Advanced Materials/Nanotechnology, Biomaterials, Manufacturing/Construction/Mechanical

Skin-on-a-Chip Microfluidic Device

Dermatology and beauty product research and development and testing has been limited to animal testing, which in some countries has been banned. Because of increasing controversial issues surrounding animal testing of these dermatology or beauty products, there has been increasing interest in developing in-vivo like in-vitro models for skin research. ...

Published: 2/26/2026 | Updated: 6/11/2025 | Inventor(s): Mehdi Nikkhah, Shaun Wootten, Ronin-Mae Komarnisky

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Life Science (All LS Techs), Biomaterials, Medical Devices

A novel Scaffold for Mode-Selective Inhibition of TRPV1

Pain is estimated to affect about 30% of the world’s population and treatment is challenging because of issues with addiction and withdrawal which accompany many current analgesics. Human TRPV1 is a widely expressed nociceptor and is a desirable target to modulate diverse human pathophysiologies, including pain, obesity, and diabetes, among others....

Published: 2/26/2026 | Updated: 4/2/2025 | Inventor(s): Wade Van Horn, Pankaj J. Pasricha

Keywords(s):

Category(s): Life Science (All LS Techs), Non-Cancer Therapeutics, Pharmaceuticals, Advanced Materials/Nanotechnology, Artificial Intelligence/Machine Learning, Biomaterials

Biomaterial for Preventing Postoperative Intestinal Adhesions

Intra-abdominal adhesions, also known as postoperative peritoneal adhesions (PPA) remain a challenging issue in the US healthcare system. It is estimated that over 90% of gastrointestinal (GI) surgical procedures result in PPA formation, regardless of the location or surgical technique used. PPAs can also develop in response to tissue damage caused...

Published: 2/26/2026 | Updated: 2/20/2025 | Inventor(s): Kaushal Rege, Vanshika Singh, Muhammad Raisul Abedin, Jordan Yaron

Keywords(s):

Category(s): Biomaterials, Life Science (All LS Techs), Manufacturing/Construction/Mechanical, Medical Devices

Metabolic Reprogramming of Immune for Autoimmune Disorders Prevention/Reversal

Antigen-specific immune suppression or tolerance is a highly attractive strategy to prevent inflammation-induced tissue damage in rheumatoid arthritis (RA). Although there is insufficient knowledge about autoantigens in human RA, generating and expanding synovium-specific regulatory T cells, and suppressing synovium-specific follicular T-helper cells,...

Published: 2/26/2026 | Updated: 2/19/2025 | Inventor(s): Abhinav Acharya, Joslyn Mangal

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Biomaterials, Life Science (All LS Techs), Non-Cancer Therapeutics, Nucleic Acid/Peptide/Protein Therapies, Pharmaceuticals

Neutrophil based CAR Therapies for Treatment

Chimeric antigen receptor (CAR)-T-cell-based immunotherapies have dramatically improved survival in cancer patients. Unfortunately, CAR-T cell therapies are associated with severe neurotoxicity, adverse events during clinical trials, and cytokine storm syndrome among others. Therefore, there is a great need to develop strategies that can keep the benefits...

Published: 2/26/2026 | Updated: 2/19/2025 | Inventor(s): Abhinav Acharya, Mamta Wankhede

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Biomaterials, Cancer, Cancer Therapeutics, Life Science (All LS Techs), Pharmaceuticals, Nucleic Acid/Peptide/Protein Therapies

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